The Relation of Preterm Birth and Microbiota

Abstract

One hundred trillion of symbiotic bacterial cells in every human being make up the human microbiota. Microbiota protects tissues from antigens and pathogens by increasing mucosal barrier resistance. In pregnancy there are changes in the female body, especially in the vaginal microbial. In studies, it has been reported that this alteration inhibits pathogenesis by the secretion of antibacterial bacteriocins such as lactic acid, which can maintain acid pH. The impaired vaginal environment is associated with pregnancy complications, especially with the risk of preterm birth. This study discusses the relationship between preterm birth and microbiota.

Keywords

• Preterm birth,microbiota,pregnancy

Erken Doğum ve Mikrobiyota İlişkisi

Abstract

Her insanda bulunan yüz trilyon simbiyotik bakteri hücresi insan mikrobiyotasını oluşturmaktadır. Mikrobiyota, mukozal bariyer direncini artırarak dokuları antijen ve patojenlerden korumaktadır. Gebelikte kadın vücudunda, özellikle de vajinal mikrobiyumda değişimler olmaktadır.  Çalışmalarda bu değişikliğin, asit pH'ını koruyabilen laktik asit gibi antibakteriyel bakteriyosinlerin salgılanması yoluyla patojen gelişimini inhibe ettiği bildirilmektedir. Bozulmuş vajinal ortam gebelik komplikasyonlarıyla özellikle erken doğum riski ile ilişkilendirilmektedir. Bu çalışmada erken doğum ve mikrobiyata ilişkisi tartışılmaktadır.

Keywords

• Erken doğum,mikrobiyota,gebelik

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