Investigation of Relationship with COVID-19 and Acute Pancreatitis

Abstract

More than 2 million people worldwide have died due to coronavirus disease-19 (COVID-19). The severity of the disease ranges from subclinical infections to severe illnesses requiring hospitalization. SARS-CoV-2, which is the causative agent of COVID-19 disease, mainly affects the respiratory tract, but gastrointestinal symptoms such as nausea, vomiting and diarrhea may also occur. Abdominal pain is one of the known symptoms associated with COVID-19 disease. There are a few data on the development of acute pancreatitis as a complication of severe COVID-19 infection. Some patients with COVID-19 may develop an elevated pancreatic enzyme and rarely acute pancreatitis. This situation is associated with a particularly serious clinical picture. The mechanism of pancreatic involvement in COVID-19 is not clearly understood. In this review, it was aimed to evaluate COVID-19 associated pancreatitis.

Keywords

• COVID-19
• acute pancreatitis
• SARS-CoV-2

COVID-19-Akut Pankreatit İlişkisinin İncelenmesi

Abstract

Koronavirüs hastalığı-19 (COVID-19) pandemisi şu an için dünya çapında iki milyondan fazla insanın ölümüne neden olmuştur. Hastalığın ciddiyeti subklinik infeksiyonlardan hastaneye yatmayı gerektiren ağır hastalığa kadar değişmektedir. COVID-19 hastalık etkeni olan SARS-CoV-2 esas olarak solunum yolunu etkiler, ancak mide bulantısı, kusma ve ishal gibi gastrointestinal semptomlar da ortaya çıkabilmektedir. Karın ağrısı, COVID-19 hastalığı ile ilişkili bilinen semptomlardan biridir. Şiddetli COVID-19 infeksiyonunun bir komplikasyonu olarak akut pankreatit gelişimi hakkında çok az veri bulunmaktadır. COVID-19 hastalarının bazılarında pankreas enzim yüksekliği ve nadir de olsa akut pankreatit gelişebilmektedir. Bu durum özellikle ciddi klinik tablo ile ilişkilidir. COVID-19’da pankreas tutulum mekanizması net anlaşılamamıştır. Bu derlemede COVID-19 ilişkili pankreatitin değerlendirilmesi amaçlanmıştır.

Keywords

• COVID-19
• akut pankreatit
• SARS-CoV-2

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