Kardiyovasküler Hastalıklar ve Mental Problemlerin İlişkisi

Yıl 2024, Sayı: 23, 954 - 967, 31.08.2024

Çağıl Ertürk , Aişe Sümeyye Küçükali , Aydın Arslan

https://doi.org/10.38079/igusabder.1450641

Öz

Kardiyovasküler hastalıklar (KVH) genellikle kalp ve damar sistemini etkileyen hastalıkların genel bir adıdır. Bu hastalıklar arasında koroner arter hastalığı, kalp yetmezliği, kalp krizi ve inme gibi durumlar bulunmaktadır. Son yıllarda yapılan araştırmalar, kardiyovasküler hastalıkların gelişiminde nörotransmitterlerin önemli bir rol oynadığını göstermektedir. Nörotransmitterler, sinir hücreleri arasında bilgi iletimini sağlayan kimyasal bileşiklerdir. Bu bileşiklerin kalp ve damar sistemi üzerindeki etkileri, kardiyovasküler fonksiyonları düzenleme yetenekleriyle ilgilidir. Özellikle stres, duygusal faktörler ve hormonal değişiklikler, nörotransmitter salınımını etkileyerek kardiyovasküler sistemi etkileyebilir. Stresle ilişkilendirilen nörotransmitterler, özellikle adrenalin ve noradrenalin gibi, kalp atış hızını artırabilir, kan basıncını yükseltebilir ve damar tonusunu değiştirebilir. Bu fizyolojik değişiklikler, uzun vadede kardiyovasküler hastalık riskini artırabilir. Ayrıca, kronik stresin nörotransmitter düzenlemeleri üzerindeki etkileri, inflamasyon ve oksidatif stres gibi faktörler aracılığıyla kardiyovasküler hastalıkların gelişimini tetikleyebilir. Nörotransmitterlerin kardiyovasküler sistemi etkileme mekanizmaları üzerine yapılan araştırmalar, bu iki mekanizma arasında farklı alanlarda ilişkili olduğunu ortaya koymuştur. Bu bağlamda, kardiyovasküler hastalıkların nörotransmitterlerle olan kompleks ilişkisi, hem klinik hem de deneysel çalışmalarda daha fazla araştırmayı gerektirmektedir. Bu makalenin amacı bu mekanizmalar arası ilişkiyi araştırmalarla beraber göstermektir, böylece kardiyovasküler hastalıkların önlenmesi ve tedavisinde yeni yaklaşımların geliştirilmesine katkıda bulunabilir.

Anahtar Kelimeler

Kardiyovasküler hastalıklar, nörotransmitter, ruh sağlığı

Relationship Between Cardiovascular Diseases and Mental Problems

Öz

Cardiovascular disease (CVD) is a general name for diseases that usually affect the cardiovascular system. These diseases include conditions such as coronary artery disease, heart failure, heart attack and stroke. Research conducted in recent years shows that neurotransmitters play an important role in the development of cardiovascular diseases. Neurotransmitters are chemical compounds that enable the transmission of information decoupled between nerve cells. The effects of these compounds on the cardiovascular system are related to their ability to regulate cardiovascular functions. In particular, stress, emotional factors and hormonal changes can affect the cardiovascular system by affecting the release of neurotransmitters. Neurotransmitters associated with stress, especially such as adrenaline and noradrenaline, can increase heart rate, raise blood pressure, and change vascular tone. These physiological changes may increase the risk of cardiovascular disease in the long term. Also, the effects of chronic stress on neurotransmitter regulation can trigger the development of cardiovascular diseases through factors such as inflammation and oxidative stress. Research conducted on the mechanisms by which neurotransmitters affect the cardiovascular system has revealed that there is a relationship between these two mechanisms in different areas. In this context, the complex relationship of cardiovascular diseases with neurotransmitters requires further research in both clinical and experimental studies. The aim of this article is to show this inter-mechanism relationship together with research so that it can contribute to the development of new approaches to the prevention and treatment of cardiovascular diseases.

Anahtar Kelimeler

Cardiovascular diseases, neurotransmitter, mental health

Kaynakça

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