Polyphenol content and antioxidant capacity of berries: A review

Abstract

Nowadays in the world (especially in developed countries), increasing very important for human health, nutrition and protection from diseases has attracted consumer demand to foods and raw materials of high nutritional value. Berries, especially members of several families belonging to the best dietary sources of biochemical compounds. They have delicious taste and flavor, economic importance, and because of the antioxidant properties of some useful compounds, therefore, they are of great interest to researchers, nutritionists, and food technology experts. These compounds are responsible individually or in combination. For the various health benefits of berries in order to prevent the onset of chronic diseases and maintain health. In recent years, people's demand for healthy products has increased, in this way, many wild fruit species began to be cultivated in large areas. In particular, studies have focused on strawberries, currants, raspberries, blackberries, and blueberry due to their delicious taste and wide usage areas. These fruits contain high levels of phenolic compounds, anthocyanins, carotenoids, alkaloids, vitamins and have protective effects against health problems including degenerative diseases, cardiovascular diseases, diabetes, obesity and cancer and are recommended for a healthy diet. Such studies need to be developed extensively to detect and preserve important mulberry germplasm and to better understand the importance of such fruit species in the World. Berries, especially members of many families such as Rosaceae and Ericaceae are great dietary sources of biochemical compounds. these compounds (phenolic acids, flavonoids-flavonols, anthocyanins, tannins, and phenolic compounds such as ascorbic acid) are found in large amounts in berries and can function as potent antioxidants and therefore can help in the prevention and reduce of against many diseases including inflammation disorders, cardiovascular diseases, various cancers species. In summary, berries contain large amounts of phenolics and have also a high antioxidant activity and people use intensively in the last time for both healthy and their tastes.

Keywords

• Berries,antioxidant,polyphenol,health,small fruit

References

1. Adina, F., Cecilia, G., Felicia, G., Carmen, D., Ovidiu, T., (2017). Identification and Quantification of Phenolic Compounds from Red Currant (Ribes rubrum L.) and Raspberries (Rubus idaeus L.). International Journal of Pharmacology, Phytochemistry and Ethnomedicine. Vol. 6, pp 30-37
2. Aaby, K., Mazur, S., Nesic, A., Skrede, G. (2012). Phenolic compounds in strawberry (Fragaria x ananassa Duch.) fruits: Composition in 27 cultivars and changes during ripening. Food Chemistry. 86–97.
3. Adamczak, A., Buchwald, W., Zielinski, J., & Mielcarek, S. (2012). Flavonoid and organic acid content in rose hips (Rosa L., sect. Caninae dc. Em. Christ.). Acta Biologica Cracoviensia Series Botanica, 54(1).
4. Ağaoğlu, Y. S. (1986). Üzümsü Meyveler. Ankara Üniversitesi Ziraat Fakültesi Yayınları, No:984, 377s, Ankara.Aneta, W., Jan, O., Magdalena, M., Joanna, W. (2013). Phenolic profile, antioxidant and antiproliferative activity of black and red currants (Ribes spp.) from organic and conventional cultivation. International Journal of Food Science & Technology, 48(4), 715-726.
5. Bhatt, L.R., Wagle, B., Adhikari, M., Bhusal,S., Giri, A., Bhattarai, S. (2018). Antioxidant Activity, Total Phenolic and Flavonoid Content of Berberis aristata DC. and Berberis thomsoniana C.K. Schneid. from Sagarmatha National Park, Nepal. Pharmacogn J. 2018; 10(6) Suppl: s167-s171.
6. Barros L., Carvalho A.M., Morais J.S. and Ferreira I.C.F.R. (2010). Strawberry-tree, blackthorn and rose fruits: Detailed characterization in nutrients and phytochemicals with antioxidant properties. Food Chem. 120: 247–254
7. Benvenuti S., Pellati F., Melegarı M., and Bertelli D. (2004). Polyphenols, anthocyanins, ascorbic acid, and radical scavenging activity of Rubus, Ribes, and Aronia. Journal of Food Science 69: 164–169.
8. Berenji Ardestani, S., Sahari, M. A., Barzegar, M. and Abbasi, S. (2013).“Some physicochemical properties of Iranian native barberry fruits (abi and poloei): Berberis integerrima and Berberis vulgarisˮ. Journal of food and Pharmaceutical Sciences,1, pp 67- 74.

9. Bobinaitė R, Vikelis P, Rimantas-Vensutonis P (2012). Variation of total phenolics, anthocyanins, ellagic acid and radical scavenging capacity in various raspberry (Rubus spp.) cultivars. Food Chem 132: 1495-1501.
10. Brennan, R. M. (2008). Currants and Gooseberries, Temperate Fruit Crop Breeding, J.F. Hancock (ed.), Chapter 6, 177-196, Scotland, UK.
11. Butkhup, L.; Samappito, W.; Samappito, S. (2013) Phenolic composition and antioxidant activity of whyte mulberry (Morus alba L.) fruits. Int. J. Food Sci. Technol., 48, 934–940.
12. Bunea, A., Rugina D.O., Pintene, A.M., Sconta, Z., Bunea C.I., Socaıcu, C., (2011). Comparative Polyphenolic Content and Antioxidant Activities of Some Wild and Cultivated Blueberries from Romania. Not Bot Horti Agrobo, 2011, 39(2):70-76.
13. Cassidy, A., Mukamal, K. J., Liu, L. (2013). High anthocyanin intake is associated with a reduced risk of myocardial infarction in young and middle-aged women. Circulation, 127(2), 188–196.
14. Castillo del Ruiz, M. Z. and Dobson, G. (2002). Varietal differences in terpene composition of blackcurrant (Ribes nigrum L.) berries by solid phase microextraction/gas chromatography. Journal of Agricultural and Food Chemistry, 82, 1510-1515.
15. Casto, B.C., Kresty, L.A., Kraly, C.L., Pearl, D.K., Knobloch, T.J. (2002). Chemoprevention of oral cancer by black raspberries. Anticancer Res. 22, 4005- 4015.
16. Carlton, P.S., Kresty L.A., Siglin, J.C., Morse, M.A., Lu, J. (2001). Inhibition of n-nitrosomethylbenzylamine-induced tumorigenesis in the rat esophagus bu dietary freeze-dried strawberries. Carcinogenesis. 22, 441-446.
17. Celik F., Kazankaya A. and Ercisli S. (2009). Fruit characteristics of some selected promising rose hip (Rosa spp.) genotypes from Van region of Turkey. Afr. J. Agric. Res. 4(3): 236-240.
18. Chanyotha, A., Techametheekul, K.W., Setthayanond, J., (2019). DDevelopment and Antioxidant Activity Analysis of Bio-Cellulose Containing Indian Gooseberry Extract. International Journal of Engineering and Advanced Technology (IJEAT) ISSN: 2249 – 8958, Volume-8, Issue-3S, February 2019.
19. Chiang, C. J., Kadouh, H., & Zhou, K. (2013). Phenolic compounds and antioxidant properties of gooseberry as affected by in vitro digestion. LWT-Food Science and Technology, 51(2), 417-422.
20. Correa-Betanzo, J., Allen-Vercoe, E., McDonald, J., Schroeter, K., Corredig, M., Paliyath, G. (2014). Stability and biological activity of wild blueberry (Vaccinium angustifolium) polyphenols during simulated in vitro gastrointestinal digestion. Food Chem, 165, 522–531.
21. Dvaranauskaitė, A., Venskutonis, P. R., Raynaud, C., Talou, T., Viškelis, P., & Sasnauskas, A. (2009). Variations in the essential oil omposition in buds of six blackcurrant (Ribes nigrum L.) cultivars at various development phases.Food Chemistry, 114(2), 671-679.
22. de Ancos, B., Gonzalez, E. M., & Cano, M. P. (2000). Ellagic acid, vitamin C, and total phenolic contents and radical scavenging capacity affected by freezing and frozen storage in raspberry fruit. Journal of Agricultural and Food Chemistry, 48, 4565–4570.
23. Demir F. and Özcan M. 2001. Chemical and technological properties of rose (Rosa canina L.) fruits grown wild in Turkey. J. Food Eng. 47: 333–336
24. Demir, F., and Kalyoncu, I. H. (2003). Some nutritional, pomological and physical properties of cornelian cherry (Cornus mas L.). Journal of Food Engineering, 60, 335–341
25. Demir, N.; Yildiz, O.; Alpaslan, M.; Hayaloglu, A. (2014). Evaluation of volatiles, phenolic compounds and antioxidant activities of rose hip (Rosa L.) fruits in Turkey. LWT Food Sci. Technol. 2014, 57, 126–133
26. De Souza, V.R.; Pereira, P.A.; da Silva, T.L.; de Oliveira Lima, L.C.; Pio, R.; Queiroz, F. (2014). Determination of the bioactive compounds, antioxidant activity and chemical composition of Brazilian blackberry, red raspberry, strawberry, blueberry and sweet cherry fruits. Food Chem., 156, 362–368.
27. Diaconeasa Z., Ranga F., Rugina, D., Leopold, L., Pop, O., Vodnar, N., Cubiu, L., Socaciu, C. (2015). Phenolic Content and Their Antioxidant Activity in Various Berries Cultivated in Romania. Bulletin UASVM Food Science and Technology 72(1).
28. Doumett, S., Fibbi, D., Cincinelli, A., Giordani, E., Nin, S., and Del Bubba, M. (2011). Comparison of nutritional and nutraceutical properties in cultivated fruits of Fragaria vesca L. produced in Italy. Food Res. Int. 44, 1209–1216. https://doi.org/10.1016/j.foodres.2010.10.044
29. Ercişli, S., (2007). Chemical composition of fruits in some rose (Rosa spp.) species. Food Chemistry 104:1379-1384.
30. Ercisli, S.; Orhan, E. (2007), Chemical composition of white (Morus alba), red (Morus rubra) and black (Morus nigra) fruits. Food Chem. 103, 1380–1384.
31. Ercisli, S.; Orhan, E. Some physico-chemical characteristics of black mulberry (Morus nigra L.) genotypes from Northeast Anatolia region of Turkey. Sci. Hortic. 2008, 116, 41–46.
32. Ercisli, S.; Tosun, M.; Duralija, B.; Voca, S.; Sengul, M.; Turan, M. (2010). Phytochemical content of some black (Morus nigra L.) and purple (Morus rubra L.) mulberry genotypes. Food Technol. Biotechnol. 2010, 48, 102–106.
33. Fattahi S., Jamei R. and Hosseini Sarghein S. 2012. Antioxidant and antiradicalic activity of Rosa canina and Rosa pimpinellifolia fruits from West Azerbaijan. Iran. J. Plant Physiol. 2(4): 523–529.
34. Gecer, M.K., Akin, M., Gundogdu, M., Eyduran, S.P, Sezai Ercisli, and Eyduran,E., (2016). Organic acids, sugars, phenolic compounds, and somehorticultural characteristics of black and white mulberry accessions from Eastern Anatolia. J. Plant Sci. 96: 27–33.
35. Gerçekçioğlu, R., Bayazıt, S., Edizer, Y., Çekic, Ç., (2009). Performance of some Currant (Ribes ssp.) Varieties in Tokat Ecology. III. National Grape Fruits Symposium, 308-313, Kahramanmaraş.
36. Gevrenova, R., Badjakov, I., Nikolovac, M., Doichinova, I., (2013). Phenolic derivatives in raspberry (Rubus L.) germplasm collection in Bulgaria. Biochemical Systematics and Ecology 50:419–427.
37. Gren, T. P.; Wyzgoski, F. J.; Reese, R. N.; Rinaldi, P. L.; Ozgen, M.; Tulio, A. Z.; Miller, A. R.; Scheerens, J. C. (2005). Identification of biologically active metabolic constituents of black raspberry using HPLC, NMR and multiple correlations with biochemical and bioassay data. AGFD-086.
38. Gorguc, A., Yıldırım, A., Takma, D., Erten, E.S., Yılmaz, F.M. (2014). Physical, chemical, bioactive and aroma properties of commercial strawberry cultivars grown in Aydın province. Harran Tarım ve Gıda Bilimleri Dergisi, 23(2): 131-141.
39. Gulcin, I., Topal, F., Çakmakcı, R., Bilsel, M., Goren, A.C., Erdogan, U., (2011). Pomological Features, Nutritional Quality, Polyphenol Content Analysis, and Antioxidant Properties of Domesticated and 3 Wild Ecotype Forms of Raspberries (Rubus idaeus L.). Journal of Food Science. Vol. 76, Nr. 4.
40. Gundogdu, M. (2013). Determination of Antioxidant Capacities and Biochemical Compounds of Berberis vulgaris L. Fruits. Advances in Environmental Biology, 7(2): 344-348.
41. Gundogdu, M., Kan, T., Canan, I (2016). Bioactive and antioxidant characteristics of blackberry cultivars from East Anatolia. Turk J Agric For (2016) 40: 344-351
42. Gundogdu, M., Tunçtürk, M.,Berk, S., Şekeroğlu, N., Gezici,S., (2018). Antioxidant Capacity and Bioactive Contents of Mulberry Species from Eastern Anatolia Region of Turkey. Indian Journal of Pharmaceutical Education and Research | Vol 52 | Issue 4 (Suppl) | Oct-Dec,
43. Halliwell, B. (1996). Antioxidants in human health and disease. Ann. Rev. Nutr. 16, 33–50.
44. Häkkinen, S., Heinonen, M., Kärenlampi, S., Mykkänen, H., Ruuskanen, J., and Törrönen, R., (1999). Screening of Selected Flavonoids and Phenolic acids in 19 Berries. Food Research Int. 32:345-353.
45. Häkkinen, S.H., Kärenlampi, S.O., Mykkänen, H.M., and Törrönen, A.R., (2000). Influence of Domestic Processing and Storage on Flavonol Contents in Berries. J. Agric. Food Chem. 48:2960-2965.
46. Imanshahidi, M. and H. Hosseinzadeh. 2008. Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytotherapy Research, 22(8): 999-1012.
47. Jabłońska-Ryś, E., Zalewska-Korona, M., and Kalbarczyk, J. (2009). Antioxidant capacity, ascorbic acid and phenolics content in wild edible fruits. J. Fruit Ornam. Plant Res. 17, 115–120.
48. Jurgiel-Małecka, G., Gibczyńska, M., Siwek, H., and Buchwał, A. (2017). Comparison of fruits chemical composition of selected cultivars wild strawberry (Fragaria vesca L.). Eur.J.Hortic.Sci. 82 (4) 204-210 | DOI: 10.17660/eJHS.2017/82.4.6.
49. Kafi, M., A. Balandary, M.H. Rashed-Mohasel, A. Koochaki and A. Molafilabi. 2004. Berberis: Production and Processing. Zaban va adab Press, Iran, pp. 1-209 (in Persian).
50. Kafkas, E.; Kosar, M.; Turemis, N.; Baser, K.H.C. (2006). Analysis of sugars, organic acids and vitamin C contents of blackberry genotypes from Turkey. Food Chemistry, v.97, p.732-736,
51. Kamiloglu, S., Serali, O., Unal, N., and Capanoglu, E., (2013). Antioxidant activity and polyphenol composition of black mulberry (Morus nigra L.) products. Journal of Berry Research 3 (2013) 41–51
52. Karaagac, H.E., and Ucurum, H.O., (2019). Investigation Of Phenolic Composition of Organically-Grown Strawberry and Blueberry. GIDA (44 (5): 794-801 doi: 10.15237/gida.GD19049.
53. Karacali, I., (2000). The Storage and Handling of Horticultural Crops, Ege University, Agricultural Faculty, Turkey (in Turkish).Katsube, N., Iwashita, K., Tsushida, T., Yamaki, K., ve Kobori, M. (2003). Induction of apoptosis in cancer cells by bilberry (Vaccinium myrtillus) and the anthocyanins. J. Agric. Food Chem. 51-68-75.
54. Khadivi-Khub, A. 2009. Pomology. Agriculture Education Press, Tehran, Iran (In Farsi).
55. Koczka, N., Stefanovits-Bányai, E., Ombódi, A., (2018). Total Polyphenol Content and Antioxidant Capacity of Rosehips of Some Rosa Species. Medicines., 5, 84. Kostecka-Gugała, A., Ledwożyw-Smoleń, I., Augustynowicz, J., Wyżgolik, G., Kruczek, M., Kaszycki, P. (2015). Antioxidant properties of fruits of raspberry and blackberry grown in central Europe. Open Chem., 2015; 13: 1313–1325.
56. Kresty, L.A., Morse, M.A., Morgan, C., Carlton, P.S., Lu, J. (2001). Chemoprevention of esophageal tumorigenesis bu dietary administration of lyophilized black raspberries. Cancer Res. 61, 6112-6119.
57. Kähkönen, M.P., Hopia, A. I., and Heinonen, M., 2001. Berry. Phenolics and Their Antioxidant Activity J. Agric. Food Chem, (49): 4076-4082
58. Laleh, G. H., Frydoonfar, H., Heidary, R., Jameei, R., & Zare, S. (2006). The effect of light, temperature, pH and species on stability of anthocyanin pigments in four Berberis species. Pakistan Journal of Nutrition, 5(1), 90-92.
59. Le Quere, J. L., & Latrasse, A. (1990). Composition of the essential oils of black currant buds (Ribes nigrum L.). Journal of Agricultural and Food Chemistry, 38(1), 3-10.Mackerras, D. (1995). Antioxidants and health. Fruits and vegetables or supplements. Food Australia. 47S, 3-23.
60. Mahmood T, Anwar F, Abbas M, Saari N. (2012). Effect of Maturity on phenolics (phenolic acids and flavonoids) profile of strawberry cultivars and mulberry species from Pakistan. International Journal of Molecular Sciences. 2012;13(4):4591-607
61. Manach C, Scalbert A, Morand C, Rémésy C, Jiménez L (2004) Polyphenols: food sources and bioavailability. Am J Clin Nutr 79: 727-747.
62. Miguel, M. G. (2011). Anthocyanins: Antioxidant and/or anti-inflammatory activities. Journal of Applied Pharmaceutical Science, 1(6), 7-15.
63. Mikulic‐Petkovsek, M., Schmitzer, V., Slatnar, A., Stampar, F., & Veberic, R. (2012). Composition of sugars, organic acids, and total phenolics in 25 wild or cultivated berry species. Journal of food science, 77(10), C1064- C1070.
64. Miret, J.A., Munné-Bosch, S. (2016). Abscisic acid and pyrabactin improve vitamin C contents in raspberries. Food Chemistry 203 :216–223
65. Nadulski, R., Masłowski, A., Mazurek, A., Sobczak, P., Szmigielski, M., Sobczak, W.Z., Niedziółka, I., Mazur, J. (2019). Vitamin C and lutein content of northern highbush blueberry (Vaccinium corymbosum L.) juice processed using freezing and thawing. Journal of Food Measurement and Characterization, 13:2521–2528.
66. Narváez-Cuenca, C.E., Mateus-Gómez, A., Restrepo-Sánchez, L.P., Antioxidant capacity and total phenolic content of air-dried cape gooseberry (Physalis peruviana L.) at different ripeness stages. gronomía Colombiana 32(2), 232-237, 2014.
67. Natic MM, Dabic DC, Papetti A, Fotiric Akšic MM, Ognjanov V, Ljubojevic M, (2015). in mulberry (Morus alba L.) fruits grown in Vojvodina, North Serbia. Food Chemistry. 2015;171:128-36.
68. Negro, C., Aprile, A., Bellis L.D., and Miceli,A. (2019). Nutraceutical Properties of Mulberries Grown in Southern Italy (Apulia). Antioxidants (Basel) 2019, 8, 223;
69. Nowak, R. (2006). Comparative study of phenolic acids in pseudofruits of some species of roses. Acta Poloniae Pharmaceutica, 63, 281e288.
70. Okatan, V. (2016). The effects of dıfferent growıng systems on the yıeld and qualıty of currant cultıvatıon. Master's thesis. Süleyman Demirel University, Institute of Science.
71. Okatan, V. (2018). Phenolic compounds and phytochemicals in fruits of black mulberry (Morus nigra L.) genotypes from the Aegean region in Turkey. Folia Hort. 30(1), 2018, 93-101
72. Okatan, V., Gündoğdu, M., Güçlü, S. F., Çelikay, A., Özaydın, A. M. Ç., Korkmaz, N., Aşkın, M. A. (2017). Phenolic Profiles of Currant (Ribes spp.) Cultivars. YYU J. Agr. Sci, 27(2), 192-196.
73. Okatan, V., Colak, A.M. (2019). Chemical and phytochemical content of barberry (Berberis vulgaris L.) fruit genotypes from sivasli district of usak province of western Turkey. Pakistan Journal of Botany; ISSN 0556-3321; Worldcat; v. 51(1); p. 165-170.
74. Ozgen M., Serçe S., Kaya C., (2009). Phytochemical and antioxidant properties of anthocyanin-rich Morus nigra and Morus rubra fruits. Sci. Hortic. 119(3), 275-279.
75. Qi,Y., Baowu, Wang, F. C., Zhiliang, H., Xi, W., Pengju, G. L. (2011). Comparison of anthocyanins and phenolics in organically and conventionally grown blueberries in selected cultivars, Food Chemistry, 125 (1) 201-208.
76. Pantelidis GE, Vasilakakis M, Manganaris GA, Diamantidis GR. (2007). Antioxidant capacity, phenol, anthocyanin and ascorbic acid contents in raspberries, blackberries, red currants, gooseberries and cornelian cherries. Food Chem 102:777–83.
77. Pel, M., Przybył, , J.L., Kosakowska, O., Szalacha, E., Szymborska, I., Węglarz, Z. (2010). Genetic and Chemical Variability of Wild Red Raspberry (Rubus idaeus L.) Growing in Poland. 4th IS on Breeding Research on Medicinal and Aromatic Plants (ISBMAP 2009) Eds.: Baričevič et al. Acta Hort. 860, ISHS 2010.
78. Píry, J., Príbela, A., Ďurčanská, J., & Farkaš, P. (1995). Fractionation of volatiles from blackcurrant (Ribes nigrum L.) by different extractive methods.Food chemistry, 54(1), 73-77.
79. Prior, R.L., Lazarus, S.A., Cao, M., Muccitelli, H., Hammerstone, F. (2001). Identification of Procyanidins and Anthocyanins in Blueberries and Cranberries (Vaccinium Spp.) Using High-Performance Liquid Chromatography/Mass Spectrometry. J. Agric. Food Chem. 2001, 49, 1270−1276.
80. Proteggente, A. R., Pannala, A. S., Paganga, G., Buren, L. V., Wagner, E., Wiseman, S., Rice-Evans, C.A. (2002). The antioxidant activity of regularly consumed fruit and vegetables reflects their phenolic and vitamin C composition. Free radical research, 36(2), 217-233.
81. Rubinskiene, M., Viskelis, P., Jasutiene, I., Viskeliene, R., & Bobinas, C. (2005). Impact of various factors on the composition and stability of black currant anthocyanins. Food research international, 38(8-9), 867-871.
82. Rodrigues, E., Poerner, N., Rockenbach, I.V., Gonzaga, L.V., Mendes, C.B., Fett, R. (2011). Phenolic compounds and antioxidant activity of blueberry cultivars grown in Brazil Compostos fenólicos e atividade antioxidante de cultivares de mirtilo produzidas no Brasil. Ciênc. Tecnol. Aliment., Campinas, 31(4): 911-917,2011
83. Roman I., Stanila A. and Stanila S. (2013). Bioactive compounds and antioxidant activity of Rosa canina L. biotypes from spontaneous flora of Transilvania. Chem. Cent. J. 7(73): 2-10Sanchez E.M., Calın-Sanchez A., Carbonell- Barrachina A.A., Melgarejo P., Hernandez F., Martinez-Nicolas J.J., 2014. Physicochemical characterization of eight Spanish mulberry clones: Processing and fresh market aptitudes. Int. J. Food Sci. Technol. 49, 477-483.
84. Salminen, J. P., Karonen, M., Lempa, K., Liimatainen, J., Sinkkonen, J., Lukkarinen, M., et al. (2005). Characterisation of proanthocyanidin aglycones and glycosides from rose hips by high-performance liquid chromatographyemass spectrometry, and their rapid quantification together with vitamin C. Journal of Chromatography A, 1077, 170e180.
85. Scalzo, J., Stevenson, D., Hedderley, D. (2013). Blueberry estimated harvest from seven new cultivars: Fruit and anthocyanins. Food Chem, 139, 44–50.
86. Schwartz, J.L. (1996). The dual roles of nutrients as antioxidants and prooxidants: their effects on tumorcell growth. J. Nutr. 126S, 1221-1227.
87. Sharifi, F., Poorakbar, L., (2015). The survey of antioxidant properties of phenolic compounds in fresh and dry hybrid Barberry fruits. Cumhuriyet University Faculty of Science Science Journal (CSJ), Vol. 36, No: 3 Special Issue (2015).
88. Sharma S., Ali A, Ali J., Sahni J.K, Baboota S., (2013). Rutin: therapeutic potential and recent advances in drug delivery. Expert Opin Investig Drugs. 2013 Aug;22(8):1063-79.
89. Sasikumar, J. M., Maheshu, V., Smilin, A. G., Gincy, M. M. and Joji, C. (2012).“Antioxidant and antihemolytic activities of common Nilgiri barberry (Berberis tinctoria Lesch.) from south Indiaˮ. International Food Research Journal, 19 (4), 1601- 1607.
90. Silva Pinto, M., Lajolo, F. M., & Genovese, M. I. (2008). Bioactive compounds and quantification of total ellagic acid in strawberries (Fragaria x ananassa Duch.). Food Chemistry, 107(4), 1629-1635.
91. Skrovankova, S., Sumczynski, D., Mlcek, J, Jurikova, T., Sochor, J. (2015). Bioactive Compounds and Antioxidant Activity in Different Types of Berries. Int. J. Mol. Sci. 2015, 16, 24673-24706; doi:10.3390/ijms161024673.
92. Sood, P., Modgil R., Sood., M. (2010). Physico- chemical and nutitional evalaluation of indigenous wild fruit kasmal berberis lycium royle . Indian journal of natural products and resources. Vom 1(3). P. 362-366. 2010
93. Stoner, G.D., Kresty, L.A., Carlton, P.S., Siglin, J.C. ve Morse, M.A. (1999). Isothiocyanates and freeze-dried strawberries as inhibitors of esophagel cancer. Toxicol Sci. 52, 95-100.
94. Stevensona, S., and Scalzob, J., (2012). Anthocyanin composition and content of blueberries from around the world. Journal of Berry Research 2 (2012) 179–189. Tabart, J., Kevers, C., Evers, D., & Dommes, J. (2011). Ascorbic Acid, Phenolic Acid, Flavonoid and Carotenoid profiles of selected extracts from Ribes nigrum. Journal of Agricultural and Food Chemistry, 59, 4763-70
95. Tosun, I. and Yüksek, S. (2003). Antioxidant capacity of small fruits, Gıda, 28(3), 305-311.
96. Tosun, M. , Ercisli, S., Karlidag, H., and Sengul. M. (2009). Characterization of Red Raspberry (Rubus idaeus L.) Genotypes for Their Physicochemical Properties. Journal Of Food Sci. Vol. 74, Nr. 7.
97. Türkben, C.; Uyla¸ser, V.; ˙Incedayı, B.; Çelikkol, I., (2010). Effects of different maturity periods and processes on nutritional components of rose hip (Rosa canina L.). J. Food Agric. Environ. 2010, 8, 26–3.
98. Uggla, M., Gustavsson, K-E., Olsson, M. E., & Nybom, H. (2005).Changes in colour and sugar content in rose hips (Rosa dumalis L. andRosa rubiginosa L.) during ripening. Journal of Horticultural Sciences and Biotechnology, 80(2), 204–208.
99. Vagiri, M. R. (2012). Black currant (Ribes nigrum L.)-an insight into the crop. [http://pub.epsilon.slu.se/8586/7/vagiri_m_120206.pdf].
100. Villano, D., Fernández-Pachón, M. S., Moyá, M. L., Troncoso, A. M., & GarcíaParrilla, M. C. (2007). Radical scavenging ability of polyphenolic compounds towards DPPH free radical. Talanta, 71(1), 230-235.
101. Wang S.Y., Lin H.S., Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage, J. Agric. Food Chem., 2000, 48, 140-146.
102. Wang, Z.; Cang, T.; Qi, P.; Zhao, X.; Xu, H.; Wang, X.; Zhang, H.; Wang, X. (2015). Dissipation of four fungicides on greenhouse strawberries and an assessment of their risks. Food Control. 55, 215–220
103. Wang, H., Guo, X., Hu, X., Li, T., Fu, X., Liu, R.H., Comparison of Phytochemical Profiles,Antioxidant and Cellular Antioxidant Activities in Different Varieties of Blueberry (Vaccinium Spp) (2016), Food Chemistry doi: http://dx.doi.org/10.1016/j.foodchem.2016.09.002.
104. Wang, H., Guo, X., Hu, X., Li, T., Fu, X., & Liu, R. H. (2017). Comparison of phytochemical profiles, antioxidant and cellular antioxidant activities of different varieties of blueberry (Vaccinium spp.). Food Chemistry, 217, 773–781.
105. Wolfe, K.L. (2008). Cellular antioxidant activity of common fruits. Journal of Agricultural of Food Chemistry, v. 56, p. 8418- 8426, 2008. PMid:18759450.http://dx.doi.org/10.1021/jf801381y7
106. Xue, H., Aziz, R.M., Sun, N., Cassady, J.M., Kamendulis, L.M. (2001). Inhibition of celluar transformation by berry extracts. Carcinogenesis. 22, 351- 356.
107. Yildiz, H., Ercisli, S., Hegedus, A., Akbulut, M., Topdas, E.F. (2014). Bioactive content and antioxidant characteristics of wild (Fragaria vesca L.) and cultivated strawberry (Fragaria × ananassa Duch.) fruits from Turkey. . Aliman Journal of Applied Botany and Food Quality 87, 274 - 278
108. Yilmaz, S.O., and Ercisli, S. (2011). Antibacterial and antioxidant activity of fruits of some rose species from Turkey. Rom. Biotechnol. Lett. 2011, 16, 6407–6411.Zia-Ul-Haq, M., Riaz, M., De Feo, V., Hawa Z. E. Jaafar, and Moga, M., (2014). Rubus Fruticosus L.: Constituents, Biological Activities and Health Related Uses. Molecules 2014, 19, 10998-11029.
109. Zorenc, Z., Veber, R., Stampar, F., Koron, D., Mikulic-Petkovsek, M. (2016). Changes in berry quality of northern highbush blueberry (Vaccinium corymbosum L.) during the harvest season. Turk J Agric For, 40: 855-864.