Determination of phenolic compounds in Nasturtium Officinale by LC-MS / MS using different extraction methods and different solvents

Year 2023, Volume: 7 Issue: 2, 124 - 130, 31.12.2023

Leyla Ercan , Mehmet Doğru

https://doi.org/10.32571/ijct.1150482

Abstract

This study aimed to determine the phenolic compound contents of Nasturtium officinale (N. officinale) extracts prepared with water, methanol, ethanol, and chloroform, as well as extracts prepared by evaporation and lyophilization, and parts of N. officinale by LC-MS/MS (Liquid Chromatography-Mass spectrometry/Mass spectrometry). The results obtained not only contribute to knowledge about the benefits of N. officinale but also show the effect of different solvents and different extraction methods on the determination of phenolic compounds. In addition to these results, the importance of the cold chain in the determination of some phenolic compounds has also been demonstrated. While it is observed that the number of phenolic components obtained from the extracts prepared with methanol and ethanol is high; It is observed that some phenolic compounds such as quinic acid, fumaric acid, aconitic acid, and p-coumaric acid dissolve very well in water and temperature is important.

Keywords

Phenolic components, LC-MS/MS, Nasturtium officinale, quinic acid, extraction

Supporting Institution

Dicle University Scientific Research Projects Coordination Unit.

Project Number

ZGEF.20.001

Thanks

We are grateful to Dicle University Science and Technology Application and Research Center (DÜBTAM) for the analysis. Also, for his contributions, we would like to thank Prof. Dr. Hasan AKAN.

References

• 1. Barker, D.J. FSH 2009, 423.
• 2. Cartea, M.E.; Francisco, M.; Soengas, P.; Velasco, P. Molecules 2010, 16(1), 251–280.
• 3. Casanova, N.A.; Ariagno, J.I.; López Nigro, M.M.; Mendeluk, G.R.; Gette, M. de los A.; Petenatti, E; Palaoro, LA; Carballo, MA J Appl Toxicol 2013, 33(9), 880–885.
• 4. Shahani, S.; Behzadfar, F.; Jahani, D.; Ghasemi, M.; Shaki, F. Toxicol Mech Methods 2017, 27(2), 107–114.
• 5. Gonçalves, E.M.; Cruz, R.M.S.; Abreu, M.; Brandão, T.R.S.; Silva, C.L.M. J Food Eng. 2009, 93(1), 32–39.
• 6. Pourhassan-Moghaddam, M.; Zarghami, N.; Mohsenifar, A.; Rahmati-Yamchi, M.; Gholizadeh, D.; Akbarzadeh, A.; De La Guardia, M.; Nejati-Koshki, K. Micro Nano Lett. 2014, 9(5), 345–350.
• 7. Camponogara, C.; Silva, C.R.; Brusco, I.; Piana, M.; Faccin, H.; de Carvalho, L.M.; Schuch, A.; Trevisan, G.; Oliveira, S.M. J Ethnopharmacol 2019, 229, 190–204.
• 8. Mehrabi, S.; Askarpour, E.; Mehrabi, F.; Jannesar, R. J Nephropathol 2016, 5(4), 127.
• 9. Akhzari, D.; Pessarakli, M. Commun Soil Sci Plant Anal. 2022, 53(11), 1326–1333.
• 10. Zeng, K.; Thompson, K.E.; Yates, C.R.; Miller, D.D. Bioorg Med Chem Lett. 2009, 19(18), 5458–5460.
• 11. Del Rio, D.; Rodriguez-Mateos, A.; Spencer, J.P.E.; Tognolini, M.; Borges, G.; Crozier, A. Antioxid Redox Signal 2013, 18(14), 1892.
• 12. Albuquerque, B.R.; Heleno, S.A.; Oliveira, M.B.P.P.; Barros, L.; Ferreira, I.C.F.R. Food Funct. 2021, 12(1), 14–29.
• 13. Caleja, C.; Ribeiro, A.; Barreiro, M.F.; Ferreira, I.C.F.R. Curr Pharm Des. 2017, 23(19), 2787–2806.
• 14. Jiang, Y.; Pei, J.; Zheng, Y.; Miao, Y.J.; Duan, B.Z.; Huang, L.F. Chin J Integr Med. 2022, 28(7), 661–671.
• 15. Patel, S.S.; Goyal, R.K. Pharmacognosy Res. 2011, 3(4), 239–245.
• 16. Ercan, L.; Doğru, M. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi 2022, 11(4), 1018–1025.
• 17. Bajkacz, S.; Baranowska, I.; Buszewski, B.; Kowalski, B.; Ligor, M. Food Anal Methods 2018, 11(12), 3563–3575.
• 18. Yilmaz, M.A. Ind Crops Prod. 2020, 149, 112347.
• 19. Nzekoue, F.K.; Angeloni, S.; Navarini, L.; Angeloni, C.; Freschi, M.; Hrelia, S.; Vitali, L.A.; Sagratini, G.; Vittori, S.; Caprioli, G. Food Research International 2020, 133, 109128.
• 20. Ye, F.; Liang, Q.; Li, H.; Zhao, G. Ind Crops Prod. 2015, 76, 574–581.
• 21. Bursal, E.; Aras, A.; Kılıç, Ö. Nat Prod Res. 2019, 33(13), 1975–1979.
• 22. Ozen, T.; Demirtas, İ. International Journal of Chemistry and Technology 2021, 5(1), 67–76.
• 23. Ercan, L.; Doğru, M. Su Teresi (Nasturtium officinale) Bitkisinin Antioksidan Kapasitesinin Belirlenmesi, Doktora Tez, Dicle Üniversitesi, Diyarbakır, 2021.
• 24. Naczk, M.; Shahidi, F. J Pharm Biomed Anal. 2006, 41(5), 1523–1542.
• 25. Boeing, J.S.; Barizão, É.O.; e Silva, B.C.; Montanher, P.F.; de Cinque A.V.; Visentainer, J.V. Chem Cent J. 2014, 8(1), 48.
• 26. Zeb, A. Springerplus 2015, 4(1), 1–7.
• 27. Zeb, A.; Habib, A. Journal of Food Measurement and Characterization 2018, 12(4), 2677–2684.
• 28. Wang, G.F.; Shi, L.P.; Ren, Y.D.; Liu, Q.F.; Liu, H.F.; Zhang, R.J.; Li, Z.; Zhu, F.H.; He, P.L.; Tang, W.; Tao, P.Z.; Li, C.; Zhao, W.M.; Zuo, JP Antiviral Res. 2009, 83(2), 186–190.
• 29. Arya, A.; Al-Obaidi, M.M.J.; Shahid, N.; Bin Noordin, M.I.; Looi, C.Y.; Wong, W.F.; Khaing, S.L.; Mustafa, M.R. Food and Chemical Toxicology 2014, 71, 183–196.
• 30. Kanitkar, A.; Aita, G.; Madsen, L. Journal of Chemical Technology & Biotechnology 2013, 88(12), 2188–2192.
• 31. Yazdi, M.R.; Mrowietz, U. Clin Dermatol. 2008, 26(5), 522–526.
• 32. Gold, R.; Linker, R.A.; Stangel, M. Clin Immunol. 2012, 142(1), 44–48.
• 33. Haghikia, A.; Linker, R.; Gold, R. Nervenarzt 2014, 85(6), 720–726.
• 34. Boo, Y.C. Antioxidants 2019, 8(8), 275.
• 35. Ali, A.M.; Gabbar, M.A.; Abdel-Twab, S.M.; Fahmy, E.M.; Ebaid, H.; Alhazza, I.M.; Ahmed, O.M. Oxid Med Cell Longev. 2020, 2020, 1730492.
• 36. Vijayvergia, U.; Bandyopadhayaya, S.; Mandal, C.C. Pharmacotherapeutic Botanicals for Cancer Chemoprevention 2020, 197–219.
• 37. Pandey, P.; Khan, F. Nutrition Research 2021, 92, 21–31.