Anti-Proliferative Effect of Rosa Agrestis on Endometrium Cancer Cells In Vitro
Abstract
Endometrial cancer is the most common gynaecological malignant disease. Despite of some arguments about the preference of herbal medicine to pharmaceutical drugs, because of their minimal side effects herbal medicine is proven to be effective as a single application and/or an adjuvant therapy. Rosa agretis Savi R. agretis Savi which belongs to Rosaceae family has been used traditionally to treat allergy, antiatopic dermatitis, and some inflammatory diseases, is commonly studied. Anti-oxidant activity is also reported. The present study was undertaken to investigate the in vitro anticancer activity of R. agrestis parts leaves, flowers at endometrium cancer. Extracts in a concentration of 1 µg/ml to 200 µg/ml from leaves and flowers were tested on human endometrium cell line named Ischikawa for 72 h. Cell proliferation total cell number and apoptotic index flow cytometry were evaluated for 72 h. All the results were statistically analyzed using the independent Student’s t-test. All extracts decreased cell number and increased apoptotic index with dead cells in concentration and time dependent manner p
Keywords
References
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Details
Primary Language
English
Subjects
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Journal Section
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Publication Date
June 1, 2015
Submission Date
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Acceptance Date
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Published in Issue
Year 2015 Volume: 1 Number: 1
APA
Ergüven, M., Kültür, S., & Özsoy, N. (2015). Anti-Proliferative Effect of Rosa Agrestis on Endometrium Cancer Cells In Vitro. International Journal of Food Engineering Research, 1(1), 17-23. https://doi.org/10.17932/ IAU.IJFER.m.21495777.2015.1/1.17-23
AMA
1.Ergüven M, Kültür S, Özsoy N. Anti-Proliferative Effect of Rosa Agrestis on Endometrium Cancer Cells In Vitro. IJFER. 2015;1(1):17-23. doi:10.17932/ IAU.IJFER.m.21495777.2015.1/1.17-23
Chicago
Ergüven, Mine, Sükran Kültür, and Nurten Özsoy. 2015. “Anti-Proliferative Effect of Rosa Agrestis on Endometrium Cancer Cells In Vitro”. International Journal of Food Engineering Research 1 (1): 17-23. https://doi.org/10.17932/ IAU.IJFER.m.21495777.2015.1/1.17-23.
EndNote
Ergüven M, Kültür S, Özsoy N (June 1, 2015) Anti-Proliferative Effect of Rosa Agrestis on Endometrium Cancer Cells In Vitro. International Journal of Food Engineering Research 1 1 17–23.
IEEE
[1]M. Ergüven, S. Kültür, and N. Özsoy, “Anti-Proliferative Effect of Rosa Agrestis on Endometrium Cancer Cells In Vitro”, IJFER, vol. 1, no. 1, pp. 17–23, June 2015, doi: 10.17932/ IAU.IJFER.m.21495777.2015.1/1.17-23.
ISNAD
Ergüven, Mine - Kültür, Sükran - Özsoy, Nurten. “Anti-Proliferative Effect of Rosa Agrestis on Endometrium Cancer Cells In Vitro”. International Journal of Food Engineering Research 1/1 (June 1, 2015): 17-23. https://doi.org/10.17932/ IAU.IJFER.m.21495777.2015.1/1.17-23.
JAMA
1.Ergüven M, Kültür S, Özsoy N. Anti-Proliferative Effect of Rosa Agrestis on Endometrium Cancer Cells In Vitro. IJFER. 2015;1:17–23.
MLA
Ergüven, Mine, et al. “Anti-Proliferative Effect of Rosa Agrestis on Endometrium Cancer Cells In Vitro”. International Journal of Food Engineering Research, vol. 1, no. 1, June 2015, pp. 17-23, doi:10.17932/ IAU.IJFER.m.21495777.2015.1/1.17-23.
Vancouver
1.Mine Ergüven, Sükran Kültür, Nurten Özsoy. Anti-Proliferative Effect of Rosa Agrestis on Endometrium Cancer Cells In Vitro. IJFER. 2015 Jun. 1;1(1):17-23. doi:10.17932/ IAU.IJFER.m.21495777.2015.1/1.17-23
