A Review of Approaches in Steviol Glycosides Synthesis

Year 2019, , 145 - 157, 28.12.2019

Nurul Hidayah Samsulrizal , Zarina Zainuddin Abdul Latif Noh Tamil Chelvan Sundram

https://doi.org/10.38001/ijlsb.577338

Cited By: 7

Abstract

Stevia
rebaudiana (Bertoni) is a commercially important plant
worldwide. The leaves of stevia contain steviol glycosides which are non-caloric
and high-potency sweeteners. They are suitable for substituting sucrose and
other artificial sweetening agents. Stevia also has many therapeutic properties
such as antidiabetic, anti-cariogenic, antimicrobial, anticancer and antioxidative.
Rebaudioside A and stevioside are the major glycosides produced in stevia
leaves. Development of new varieties of Stevia rebaudiana with a greater
content of rebaudioside A and decreased content of stevioside is the main concern.
This is due to rebaudioside A having a more desirable sweet flavour taste than
stevioside which possesses bitter aftertaste. In respect to that, many biotechnological
approaches are available for the industrial improvement and manipulation of steviol
glycosides content in stevia. Transcriptome profiling has emerged as a useful
tool to identify target genes involved in the steviol glycosides biosynthesis
pathway. Understanding the mechanism and biosynthesis pathway of these
compounds can help to improve the glycosides profile by up-regulating and
down-regulating desired genes. The aim of this paper is to describe the latest
development in the transcriptome profiling in stevia as well as to discuss the
methods used in this endeavour.

Keywords

Stevia, Stevia rebaudiana, steviol glycoside, transcriptome

Supporting Institution

International Islamic University Malaysia, 25200 Kuantan, Pahang, Malaysia

Project Number

RIGS17-022-0597

Thanks

We thank International Islamic University Malaysia (IIUM) Research Initiative Grant Scheme (RIGS17-022-0597) for supporting this work.

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