Analysis of Phytochemical Composition and Biological Activities of Verbascum cheiranthifolium var. cheiranthifolium stem and flowers

Abstract

Within this study phytochemical composition, antioxidant and enzyme inhibitory activities of extracts obtained from stem and flower of Verbascum cheiranthifolium var. cheiranthifolium were analysed. Both of the extracts were detected as rich sources of phenolics (verbascoside and luteolin hexoside), various volatile and fatty acid compounds. Luteolin hexoside rich stem extract had pronounced FCR, FRAP and α-glucosidase inhibitory activities. Flower extract had high levels of ORAC assay and effectively suppressed activity of pancreatic lipase enzyme, which was rich in verbascoside compound. Phenolic compounds and volatile compounds present in the extracts might be the main contributors of antioxidant capacity and enzyme inhibitory activities of the stem and flower extracts. Pronounced antioxidant and enzyme inhibitory activities and rich bioactive composition determined in this study reveal that Verbascum cheiranthifolium var. cheiranthifolum extracts might be a good source for natural health attributing sources.

Keywords

• Antioxidant
• α-Glucosidase
• Pancreatic Lipase
• Phenolics

Analysis of Phytochemical Composition and Biological Activities of Verbascum cheiranthifolium var. cheiranthifolium stem and flowers

Abstract

Within this study phytochemical composition, antioxidant and enzyme inhibitory activities of extracts obtained from stem and flower of Verbascum cheiranthifolium var. cheiranthifolium were analysed. Both of the extracts were detected as rich sources of phenolics (verbascoside and luteolin hexoside), various volatile and fatty acid compounds. Luteolin hexoside rich stem extract had pronounced FCR, FRAP and α-glucosidase inhibitory activities. Flower extract had high levels of ORAC assay and effectively suppressed activity of pancreatic lipase enzyme, which was rich in verbascoside compound. Phenolic compounds and volatile compounds present in the extracts might be the main contributors of antioxidant capacity and enzyme inhibitory activities of the stem and flower extracts. Pronounced antioxidant and enzyme inhibitory activities and rich bioactive composition determined in this study reveal that Verbascum cheiranthifolium var. cheiranthifolum extracts might be a good source for natural health attributing sources.

Keywords

• Antioxidant
• α-Glucosidase
• Pancreatic Lipase
• Phenolics
• Volatiles

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