Research Article
BibTex RIS Cite

Determination of phenolic content of Berberis vulgaris L. fruits harvested at different times by multivariate analysis

Year 2025, Volume: 12 Issue: 3, 725 - 731, 04.09.2025
https://doi.org/10.21448/ijsm.1580988

Abstract

This study focused on the levels of phenolic compounds present in the fruits of Berberis vulgaris genotypes harvested at different times and determined the relationship between the studied traits by multivariate analysis. Harvest time significantly affected the amount of phenolic content. There were significant increases in gallic, catechin, chlorogenic, rutin, and q-coumaric acid contents, while caffeic and syringic acid contents decreased significantly as the harvest time was delayed. In PCA analysis, PC1 and PC2 explained 78.3% of the data. It was found that ‘Harvest 1’ was notable for its high content of caffeic and syringic acids, while ‘Harvest 4’ excelled in catechin, gallic acid, and chlorogenic acid content. It was also determined that ‘Genotype 1’ stood out in terms of myricetin, quercetin, p-coumaric, q-coumaric, and rutin content. This study highlights the importance of phenolic acid content in determining the optimal harvest time. The findings indicate that ‘Harvest 4’ (December) is the most suitable period for harvesting, particularly in terms of gallic acid, catechin, chlorogenic acid, p-coumaric acid, rutin, and q-coumaric acid.

References

  • Aaby, K., Ekeberg, D., & Skrede, G. (2007). Characterization of phenolic compounds in strawberry (Fragaria× ananassa) fruits by different HPLC detectors and contribution of individual compounds to total antioxidant capacity. Journal of Agricultural and Food Chemistry, 55(11), 4395-4406. https://doi.org/10.1021/jf0702592
  • Ağaoğlu, S., & Gerçekcioğlu, R. (2013). Üzümsü Meyveler [Berries]. Tomurcuk Bağ. Lim. Şti. Eğitim Yayınları, (1).
  • Akbulut, M., Çalışır, S., Marakoğlu, T., & Coklar, H. (2009). Some physicomechanical and nutritional properties of barberry (Berberis vulgaris L.) fruits. Journal of Food Process Engineering, 32(4), 497-511. https://doi.org/10.1111/j.1745-4530.2007.00229.x
  • Alavi, N., & Mazloumzadeh, S.M. (2012). Effect of harvesting and drying methods of seedless barberry on some fruit quality. Journal of the Saudi Society of Agricultural Sciences, 11, 51-55. https://doi.org/10.1016/j.jssas.2011.08.003
  • Arakawa, H., Maeda, M., Okubo, S., & Shimamura, T. (2004). Role of hydrogen peroxide in bactericidal action of catechin. Biological and Pharmaceutical Bulletin, 27(3), 277-281. https://doi.org/10.1248/bpb.27.277
  • Arena, M.E., & Curvetto, N. (2008). Berberis buxifolia fruiting: Kinetic growth behavior and evolution of chemical properties during the fruiting period and different growing seasons. Scientia Horticulturae, 118(2), 120-127. https://doi.org/10.1016/j.scienta.2008.05.039
  • Awan, M.S., Ali, S., Ali, A., Hussain, A., & Ali, M. (2014). A comparative study of barberry fruits in terms of its nutritive and medicinal contents from CKNP region, Gilgit-Baltistan, Pakistan. Journal of Biodiversity and Environmental Sciences, 5(2), 9-17.
  • Bak, T., Güler, E., & Karadeniz, T. (2021). Harvest Time Alters Fruit Quality Traits of Barberries (Berberis vulgaris). Recent Headways in Pomology Edited by Assist. Prof. Dr. Mine PAKYÜREK, Iksad Publications.
  • BenSaad, L.A., Kim, K.H., Quah, C.C., Kim, W.R., & Shahimi, M. (2017). Anti-inflammatory potential of ellagic acid, gallic acid and punicalagin A&B isolated from Punica granatum. BMC Complementary and Alternative Medicine, 17, 1-10. https://doi.org/10.1186/s12906-017-1555-0
  • Chiang, H.M., Chen, C.W., Chen, C.C., Wang, H.W., Jhang, J.H., Huang, Y.H., & Wen, K.C. (2015). Role of Coffea arabica extract and related compounds in preventing photoaging and photodamage of the skin. In Coffee in health and disease prevention (pp. 523-530). Academic Press. https://doi.org/10.1016/B978-0-12-409517-5.00058-9
  • Çakır, Ö., & Karabulut, A. (2020). Comparison of two wild-grown Berberis varieties based on biochemical characterization. Journal of Food Processing and Preservation, 44(11), e14844. https://doi.org/10.1111/jfpp.14844
  • Embuscado, M.E. (2015). Spices and herbs: Natural sources of antioxidants–a mini review. Journal of Functional Foods, 18, 811-819. https://doi.org/10.1016/j.jff.2015.03.005
  • Ercan, L. (2024). Bioactive components, antioxidant capacity, and antimicrobial activity of Berberis crataegina fruit. Pharmacological Research-Natural Products, 2, 100020. https://doi.org/10.1016/j.prenap.2024.100020
  • Eroğlu, A.Y., Çakır, Ö., Sağdıç, M., & Dertli, E. (2020). Bioactive characteristics of wild Berberis vulgaris and Berberis crataegina fruits. Journal of Chemistry, 2020, 1-9. https://doi.org/10.1155/2020/8908301
  • Espíndola, K.M.M., Ferreira, R.G., Narvaez, L.E.M., Silva Rosario, A.C.R., Da Silva, A.H.M., Silva, A.G.B., Oliveira, A.P., & Monteiro, M.C. (2019). Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma. Frontiers in Oncology, 9, 541. https://doi.org/10.3389/fonc.2019.00541
  • Fallahi, J., Rezvani Moghaddam, P., Nassiri Mohalati, M. (2010). Effect of Harvesting Date on Quantitative and Qualitative Characteristics of Seedless Barberry (Berberis vulgaris) Fruit. Iranian Journal of Field Crops Research, 8(2), 225-234. SID. https://sid.ir/paper/119402/en
  • Gholizadeh‐Moghadam, N., Hosseini, B., & Alirezalu, A. (2019). Classification of barberry genotypes by multivariate analysis of biochemical constituents and HPLC profiles. Phytochemical Analysis, 30(4), 385-394. https://doi.org/10.1002/pca.2821394
  • Gundogdu, M. (2013). Determination of antioxidant capacities and biochemical compounds of Berberis vulgaris L. Fruits. Advances in Environmental Biology, 7(2), 344-348.
  • Imenshahidi, M., & Hosseinzadeh, H. (2008). Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytotherapy Research, 22(8), 999-1012. https://doi.org/10.1002/ptr.2399
  • Imenshahidi, M., & Hosseinzadeh, H. (2016). Berberis vulgaris and berberine: an update review. Phytotherapy Research, 30(11), 1745-1764. https://doi.org/10.1002/ptr.5693
  • Javadzadeh, S.M. (2013). Effect of different methods harvesting, drying and harvest time on losses seedless barberry (Berberis vulgaris L.). Global Advanced Research Journal of Agricultural Science, 2(5), 142-147.
  • Kalmarzi, R.N., Naleini, S.N., Ashtary-Larky, D., Peluso, I., Jouybari, L., Rafi, A., ..., Kooti, W. (2019). Anti-inflammatory and immunomodulatory effects of barberry (Berberis vulgaris) and its main compounds. Oxidative medicine and cellular longevity, 2019. Hindawi Oxidative Medicine and Cellular Longevity, 2019, Article ID 6183965, 10 pages, https://doi.org/10.1155/2019/6183965
  • Karadeniz, T. (2004). Şifalı Meyveler (Meyvelerle beslenme ve tedavi şekilleri) [Medicinal Fruits (Nutrition and treatment methods with fruits)]. İstanbul: Burcan Ofset Matbaacılık Sanayi.
  • Kırca, L., & Aygün, A. (2024). Determination and comparison of morpho-physiological characteristics of Turkish sweet cherry (Prunus avium L.) grown in Afyonkarahisar: local cultivars and genotypes. Genetic Resources and Crop Evolution, 71, 4359–4373. https://doi.org/10.1007/s10722-024-01904-9
  • Kırca, L., Kırca, S., & Aygün, A. (2023). Organic Acid, Phenolic Compound and Antioxidant Contents of Fresh and Dried Fruits of Pear (Pyrus communis L.) Cultivars. Erwerbs-Obstbau, 65(4), 677-691. https://doi.org/10.1007/s10341-022-00760-0
  • Končić, M.Z., Kremer, D., Karlović, K., & Kosalec, I. (2010). Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat. Food and Chemical Toxicology, 48(8-9), 2176-2180. https://doi.org/10.1016/j.fct.2010.05.025
  • Larson, R.A. (1988). The antioxidants of higher plants. Phytochemistry, 27, 969-978.
  • Lu, Z., Nie, G., Belton, P.S., Tang, H., & Zhao, B. (2006). Structure–activity relationship analysis of antioxidant ability and neuroprotective effect of gallic acid derivatives. Neurochemistry International, 48(4), 263-274. https://doi.org/10.1016/j.neuint.2005.10.010
  • Mariod, A.A., Ibrahim, R.M., Ismail, M., & Ismail, N. (2010). Antioxidant activities of phenolic rich fractions (PRFs) obtained from black mahlab (Monechma ciliatum) and white mahlab (Prunus mahaleb) seedcakes. Food Chemistry, 118(1), 120 127. https://doi.org/10.1016/j.foodchem.2009.04.085
  • Moghaddam, P.R., Fallahi, J., Shajari, M.A., & Mahallati, M.N. (2013). Effects of harvest date, harvest time, and post-harvest management on quantitative and qualitative traits in seedless barberry (Berberis vulgaris L.). Industrial Crops and Products, 42, 30 36. https://doi.org/10.1016/j.indcrop.2012.05.007
  • Mokhber-Dezfuli, N., Saeidnia, S., Gohari, A.R., & Kurepaz-Mahmoodabadi, M. (2014) Phytochemistry and pharmacology of berberis species. Pharmacognosy Reviews, 8(15), 8. https://doi.org/10.4103%2F0973-7847.125517
  • Outaki, M., Zefzoufi, M., Sammama, A., El Gadali, K., Fdil, R., & El Gaini, L. (2023). Phenolic Compounds from Moroccan Retama monosperma L. Boiss, Berberis vulgaris L. and Ricinus communis L.: Characterization, Antioxidant Activity and Performance Criteria of the Validated Method Using UHPLC/DAD/ESI-MS. Indonesian Journal of Chemistry, 23(6). 1704-1721. https://doi.org/10.22146/ijc.87157
  • Özcan, M. (2019). Bahçe bitkilerinde üretimden tüketime geçişte en önemli aşama: Hasat [The Most Important Stage in Horticultural Crops from Production to Consumption: Harvest]. TÜRKTOB, 8(30), 12-19. https://www.turktob.org.tr/tr/dergi/sayi-30
  • Özgen, M., Saraçoğlu, O., & Geçer, E.N. (2012). Antioxidant capacity and chemical properties of selected barberry (Berberis vulgaris L.) fruits. Horticulture, Environment, and Biotechnology, 53, 447-451. https://doi.org/10.1007/s13580-012-0711-1
  • Pehluvan, M., Kaya, T., Doğru, B., & Lara, I. (2015) The effect of frozen storage on the phenolic compounds of Morus nigra L. (black mulberry) and Morus alba L. (white mulberry) fruit. Fruits, 70(2), 117-122. https://doi.org/10.1051/fruits/2015004
  • Rahimi-Madiseh, M., Lorigoini, Z., Zamani-Gharaghoshi, H., & Rafieian-Kopaei, M. (2017). Berberis vulgaris: specifications and traditional uses. Iranian Journal of Basic Medical Sciences, 20(5), 569. https://doi.org/10.22038%2FIJBMS.2017.8690
  • Saeidirad, M.H., & Mazloumzadeh, S.M. (2012). Effect of Harvest Time, Harvest and Drying Methods on Barberries. Journal of Agricultural Engineering Research, 13(1), 101-110. SID. https://sid.ir/paper/28109/en
  • Sayın, S., & Balcı, G. (2022). Biochemical Contents of Fruit and Seeds in Naturally Collected Berberis vulgaris L. Types. Erwerbs Obstbau, 64(3), 325 331. https://doi.org/10.1007/s10341-022-00652-3
  • Tan, M.C.S., Chiong, I.D., Carranza, M.S.S., Salmasan, R.M., & Oyong, G.G. (2018). Chemical characterization of Berberis vulgaris L. Var. asperma edible berries. Malaysian Journal of Analytical Sciences, 22, 579-585. https://doi.org/10.17576/mjas-2018-2204-02
  • Tomosaka, H., Chin, Y.W., Salim, A.A., Keller, W.J., Chai, H., & Kinghorn, A.D. (2008). Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry). Phytotherapy Research, 22(7), 979-981. https://doi.org/10.1002/ptr.2443
  • Bak, T., Güler, E., & Karadeniz, T. (2021). Harvest time alters fruit quality traits of barberries (Berberis vulgaris). In M. Pakyürek (Ed.), Recent Headways in Pomology (1st ed., pp. 355-375). İKSAD.
  • Wei, T., Simko, V., Levy, M., Xie, Y., Jin, Y., & Zemla, J. (2017). Package ‘corrplot’. Statistician, 56(316), e24.
  • Wickham, H. (2016). ggplot2: Elegant Graphics for Data Analysis. 2nd ed. Springer. https://doi.org/10.1007/978-3-319-24277-4
  • Yang, L., Zhang, Z., Hu, X., You, L., Khan, R.A.A., & Yu, Y. (2022). Phenolic contents, organic acids, and the antioxidant and bio activity of wild medicinal Berberis plants-as sustainable sources of functional food. Molecules, 27(8), 2497. https://doi.org/10.3390/molecules27082497
  • Zeiger, E. (1998). Chlorogenic Acid and Caffeic Acid - Review of Toxicological Literature. Research Triangle Park, North Carolina, 120 s.
  • Zuo, J., Tang, W., & Xu, Y. (2015). Anti-hepatitis B virus activity of chlorogenic acid and its related compounds. In Coffee in health and disease prevention (pp. 607-613). Academic Press. https://doi.org/10.1016/B978-0-12-409517-5.00068

Determination of phenolic content of Berberis vulgaris L. fruits harvested at different times by multivariate analysis

Year 2025, Volume: 12 Issue: 3, 725 - 731, 04.09.2025
https://doi.org/10.21448/ijsm.1580988

Abstract

This study focused on the levels of phenolic compounds present in the fruits of Berberis vulgaris genotypes harvested at different times and determined the relationship between the studied traits by multivariate analysis. Harvest time significantly affected the amount of phenolic content. There were significant increases in gallic, catechin, chlorogenic, rutin, and q-coumaric acid contents, while caffeic and syringic acid contents decreased significantly as the harvest time was delayed. In PCA analysis, PC1 and PC2 explained 78.3% of the data. It was found that ‘Harvest 1’ was notable for its high content of caffeic and syringic acids, while ‘Harvest 4’ excelled in catechin, gallic acid, and chlorogenic acid content. It was also determined that ‘Genotype 1’ stood out in terms of myricetin, quercetin, p-coumaric, q-coumaric, and rutin content. This study highlights the importance of phenolic acid content in determining the optimal harvest time. The findings indicate that ‘Harvest 4’ (December) is the most suitable period for harvesting, particularly in terms of gallic acid, catechin, chlorogenic acid, p-coumaric acid, rutin, and q-coumaric acid.

References

  • Aaby, K., Ekeberg, D., & Skrede, G. (2007). Characterization of phenolic compounds in strawberry (Fragaria× ananassa) fruits by different HPLC detectors and contribution of individual compounds to total antioxidant capacity. Journal of Agricultural and Food Chemistry, 55(11), 4395-4406. https://doi.org/10.1021/jf0702592
  • Ağaoğlu, S., & Gerçekcioğlu, R. (2013). Üzümsü Meyveler [Berries]. Tomurcuk Bağ. Lim. Şti. Eğitim Yayınları, (1).
  • Akbulut, M., Çalışır, S., Marakoğlu, T., & Coklar, H. (2009). Some physicomechanical and nutritional properties of barberry (Berberis vulgaris L.) fruits. Journal of Food Process Engineering, 32(4), 497-511. https://doi.org/10.1111/j.1745-4530.2007.00229.x
  • Alavi, N., & Mazloumzadeh, S.M. (2012). Effect of harvesting and drying methods of seedless barberry on some fruit quality. Journal of the Saudi Society of Agricultural Sciences, 11, 51-55. https://doi.org/10.1016/j.jssas.2011.08.003
  • Arakawa, H., Maeda, M., Okubo, S., & Shimamura, T. (2004). Role of hydrogen peroxide in bactericidal action of catechin. Biological and Pharmaceutical Bulletin, 27(3), 277-281. https://doi.org/10.1248/bpb.27.277
  • Arena, M.E., & Curvetto, N. (2008). Berberis buxifolia fruiting: Kinetic growth behavior and evolution of chemical properties during the fruiting period and different growing seasons. Scientia Horticulturae, 118(2), 120-127. https://doi.org/10.1016/j.scienta.2008.05.039
  • Awan, M.S., Ali, S., Ali, A., Hussain, A., & Ali, M. (2014). A comparative study of barberry fruits in terms of its nutritive and medicinal contents from CKNP region, Gilgit-Baltistan, Pakistan. Journal of Biodiversity and Environmental Sciences, 5(2), 9-17.
  • Bak, T., Güler, E., & Karadeniz, T. (2021). Harvest Time Alters Fruit Quality Traits of Barberries (Berberis vulgaris). Recent Headways in Pomology Edited by Assist. Prof. Dr. Mine PAKYÜREK, Iksad Publications.
  • BenSaad, L.A., Kim, K.H., Quah, C.C., Kim, W.R., & Shahimi, M. (2017). Anti-inflammatory potential of ellagic acid, gallic acid and punicalagin A&B isolated from Punica granatum. BMC Complementary and Alternative Medicine, 17, 1-10. https://doi.org/10.1186/s12906-017-1555-0
  • Chiang, H.M., Chen, C.W., Chen, C.C., Wang, H.W., Jhang, J.H., Huang, Y.H., & Wen, K.C. (2015). Role of Coffea arabica extract and related compounds in preventing photoaging and photodamage of the skin. In Coffee in health and disease prevention (pp. 523-530). Academic Press. https://doi.org/10.1016/B978-0-12-409517-5.00058-9
  • Çakır, Ö., & Karabulut, A. (2020). Comparison of two wild-grown Berberis varieties based on biochemical characterization. Journal of Food Processing and Preservation, 44(11), e14844. https://doi.org/10.1111/jfpp.14844
  • Embuscado, M.E. (2015). Spices and herbs: Natural sources of antioxidants–a mini review. Journal of Functional Foods, 18, 811-819. https://doi.org/10.1016/j.jff.2015.03.005
  • Ercan, L. (2024). Bioactive components, antioxidant capacity, and antimicrobial activity of Berberis crataegina fruit. Pharmacological Research-Natural Products, 2, 100020. https://doi.org/10.1016/j.prenap.2024.100020
  • Eroğlu, A.Y., Çakır, Ö., Sağdıç, M., & Dertli, E. (2020). Bioactive characteristics of wild Berberis vulgaris and Berberis crataegina fruits. Journal of Chemistry, 2020, 1-9. https://doi.org/10.1155/2020/8908301
  • Espíndola, K.M.M., Ferreira, R.G., Narvaez, L.E.M., Silva Rosario, A.C.R., Da Silva, A.H.M., Silva, A.G.B., Oliveira, A.P., & Monteiro, M.C. (2019). Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma. Frontiers in Oncology, 9, 541. https://doi.org/10.3389/fonc.2019.00541
  • Fallahi, J., Rezvani Moghaddam, P., Nassiri Mohalati, M. (2010). Effect of Harvesting Date on Quantitative and Qualitative Characteristics of Seedless Barberry (Berberis vulgaris) Fruit. Iranian Journal of Field Crops Research, 8(2), 225-234. SID. https://sid.ir/paper/119402/en
  • Gholizadeh‐Moghadam, N., Hosseini, B., & Alirezalu, A. (2019). Classification of barberry genotypes by multivariate analysis of biochemical constituents and HPLC profiles. Phytochemical Analysis, 30(4), 385-394. https://doi.org/10.1002/pca.2821394
  • Gundogdu, M. (2013). Determination of antioxidant capacities and biochemical compounds of Berberis vulgaris L. Fruits. Advances in Environmental Biology, 7(2), 344-348.
  • Imenshahidi, M., & Hosseinzadeh, H. (2008). Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytotherapy Research, 22(8), 999-1012. https://doi.org/10.1002/ptr.2399
  • Imenshahidi, M., & Hosseinzadeh, H. (2016). Berberis vulgaris and berberine: an update review. Phytotherapy Research, 30(11), 1745-1764. https://doi.org/10.1002/ptr.5693
  • Javadzadeh, S.M. (2013). Effect of different methods harvesting, drying and harvest time on losses seedless barberry (Berberis vulgaris L.). Global Advanced Research Journal of Agricultural Science, 2(5), 142-147.
  • Kalmarzi, R.N., Naleini, S.N., Ashtary-Larky, D., Peluso, I., Jouybari, L., Rafi, A., ..., Kooti, W. (2019). Anti-inflammatory and immunomodulatory effects of barberry (Berberis vulgaris) and its main compounds. Oxidative medicine and cellular longevity, 2019. Hindawi Oxidative Medicine and Cellular Longevity, 2019, Article ID 6183965, 10 pages, https://doi.org/10.1155/2019/6183965
  • Karadeniz, T. (2004). Şifalı Meyveler (Meyvelerle beslenme ve tedavi şekilleri) [Medicinal Fruits (Nutrition and treatment methods with fruits)]. İstanbul: Burcan Ofset Matbaacılık Sanayi.
  • Kırca, L., & Aygün, A. (2024). Determination and comparison of morpho-physiological characteristics of Turkish sweet cherry (Prunus avium L.) grown in Afyonkarahisar: local cultivars and genotypes. Genetic Resources and Crop Evolution, 71, 4359–4373. https://doi.org/10.1007/s10722-024-01904-9
  • Kırca, L., Kırca, S., & Aygün, A. (2023). Organic Acid, Phenolic Compound and Antioxidant Contents of Fresh and Dried Fruits of Pear (Pyrus communis L.) Cultivars. Erwerbs-Obstbau, 65(4), 677-691. https://doi.org/10.1007/s10341-022-00760-0
  • Končić, M.Z., Kremer, D., Karlović, K., & Kosalec, I. (2010). Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat. Food and Chemical Toxicology, 48(8-9), 2176-2180. https://doi.org/10.1016/j.fct.2010.05.025
  • Larson, R.A. (1988). The antioxidants of higher plants. Phytochemistry, 27, 969-978.
  • Lu, Z., Nie, G., Belton, P.S., Tang, H., & Zhao, B. (2006). Structure–activity relationship analysis of antioxidant ability and neuroprotective effect of gallic acid derivatives. Neurochemistry International, 48(4), 263-274. https://doi.org/10.1016/j.neuint.2005.10.010
  • Mariod, A.A., Ibrahim, R.M., Ismail, M., & Ismail, N. (2010). Antioxidant activities of phenolic rich fractions (PRFs) obtained from black mahlab (Monechma ciliatum) and white mahlab (Prunus mahaleb) seedcakes. Food Chemistry, 118(1), 120 127. https://doi.org/10.1016/j.foodchem.2009.04.085
  • Moghaddam, P.R., Fallahi, J., Shajari, M.A., & Mahallati, M.N. (2013). Effects of harvest date, harvest time, and post-harvest management on quantitative and qualitative traits in seedless barberry (Berberis vulgaris L.). Industrial Crops and Products, 42, 30 36. https://doi.org/10.1016/j.indcrop.2012.05.007
  • Mokhber-Dezfuli, N., Saeidnia, S., Gohari, A.R., & Kurepaz-Mahmoodabadi, M. (2014) Phytochemistry and pharmacology of berberis species. Pharmacognosy Reviews, 8(15), 8. https://doi.org/10.4103%2F0973-7847.125517
  • Outaki, M., Zefzoufi, M., Sammama, A., El Gadali, K., Fdil, R., & El Gaini, L. (2023). Phenolic Compounds from Moroccan Retama monosperma L. Boiss, Berberis vulgaris L. and Ricinus communis L.: Characterization, Antioxidant Activity and Performance Criteria of the Validated Method Using UHPLC/DAD/ESI-MS. Indonesian Journal of Chemistry, 23(6). 1704-1721. https://doi.org/10.22146/ijc.87157
  • Özcan, M. (2019). Bahçe bitkilerinde üretimden tüketime geçişte en önemli aşama: Hasat [The Most Important Stage in Horticultural Crops from Production to Consumption: Harvest]. TÜRKTOB, 8(30), 12-19. https://www.turktob.org.tr/tr/dergi/sayi-30
  • Özgen, M., Saraçoğlu, O., & Geçer, E.N. (2012). Antioxidant capacity and chemical properties of selected barberry (Berberis vulgaris L.) fruits. Horticulture, Environment, and Biotechnology, 53, 447-451. https://doi.org/10.1007/s13580-012-0711-1
  • Pehluvan, M., Kaya, T., Doğru, B., & Lara, I. (2015) The effect of frozen storage on the phenolic compounds of Morus nigra L. (black mulberry) and Morus alba L. (white mulberry) fruit. Fruits, 70(2), 117-122. https://doi.org/10.1051/fruits/2015004
  • Rahimi-Madiseh, M., Lorigoini, Z., Zamani-Gharaghoshi, H., & Rafieian-Kopaei, M. (2017). Berberis vulgaris: specifications and traditional uses. Iranian Journal of Basic Medical Sciences, 20(5), 569. https://doi.org/10.22038%2FIJBMS.2017.8690
  • Saeidirad, M.H., & Mazloumzadeh, S.M. (2012). Effect of Harvest Time, Harvest and Drying Methods on Barberries. Journal of Agricultural Engineering Research, 13(1), 101-110. SID. https://sid.ir/paper/28109/en
  • Sayın, S., & Balcı, G. (2022). Biochemical Contents of Fruit and Seeds in Naturally Collected Berberis vulgaris L. Types. Erwerbs Obstbau, 64(3), 325 331. https://doi.org/10.1007/s10341-022-00652-3
  • Tan, M.C.S., Chiong, I.D., Carranza, M.S.S., Salmasan, R.M., & Oyong, G.G. (2018). Chemical characterization of Berberis vulgaris L. Var. asperma edible berries. Malaysian Journal of Analytical Sciences, 22, 579-585. https://doi.org/10.17576/mjas-2018-2204-02
  • Tomosaka, H., Chin, Y.W., Salim, A.A., Keller, W.J., Chai, H., & Kinghorn, A.D. (2008). Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry). Phytotherapy Research, 22(7), 979-981. https://doi.org/10.1002/ptr.2443
  • Bak, T., Güler, E., & Karadeniz, T. (2021). Harvest time alters fruit quality traits of barberries (Berberis vulgaris). In M. Pakyürek (Ed.), Recent Headways in Pomology (1st ed., pp. 355-375). İKSAD.
  • Wei, T., Simko, V., Levy, M., Xie, Y., Jin, Y., & Zemla, J. (2017). Package ‘corrplot’. Statistician, 56(316), e24.
  • Wickham, H. (2016). ggplot2: Elegant Graphics for Data Analysis. 2nd ed. Springer. https://doi.org/10.1007/978-3-319-24277-4
  • Yang, L., Zhang, Z., Hu, X., You, L., Khan, R.A.A., & Yu, Y. (2022). Phenolic contents, organic acids, and the antioxidant and bio activity of wild medicinal Berberis plants-as sustainable sources of functional food. Molecules, 27(8), 2497. https://doi.org/10.3390/molecules27082497
  • Zeiger, E. (1998). Chlorogenic Acid and Caffeic Acid - Review of Toxicological Literature. Research Triangle Park, North Carolina, 120 s.
  • Zuo, J., Tang, W., & Xu, Y. (2015). Anti-hepatitis B virus activity of chlorogenic acid and its related compounds. In Coffee in health and disease prevention (pp. 607-613). Academic Press. https://doi.org/10.1016/B978-0-12-409517-5.00068
There are 46 citations in total.

Details

Primary Language English
Subjects Plant Biochemistry
Journal Section Research Article
Authors

Tuba Bak 0000-0002-4448-9704

Levent Kırca 0000-0003-2496-9513

Berna Doğru Çokran 0000-0003-4194-7826

Turan Karadeniz 0000-0003-0387-7599

Early Pub Date June 11, 2025
Publication Date September 4, 2025
Submission Date November 7, 2024
Acceptance Date February 23, 2025
Published in Issue Year 2025 Volume: 12 Issue: 3

Cite

APA Bak, T., Kırca, L., Doğru Çokran, B., Karadeniz, T. (2025). Determination of phenolic content of Berberis vulgaris L. fruits harvested at different times by multivariate analysis. International Journal of Secondary Metabolite, 12(3), 725-731. https://doi.org/10.21448/ijsm.1580988
International Journal of Secondary Metabolite

e-ISSN: 2148-6905