The frequency of cholelithiasis in inflammatory bowel disease

Abstract

Introduction: The results of studies on the frequency of cholelithiasis (CL) in patients with İnflammatory Bowel Disease (IBD) are controversial. We evaluated the frequency of CL in patients with IBD followed in our clinic. Materials and Methods: Patients with IBD followed between April 1, 2016 and December 1, 2022 were evaluated retrospectively. Results: 195 patients with IBD, 84 patients with Ulcerative Colitis (UC) and 111 with patients Crohn's Disease (CD), were included in the study. The frequency of CL increased statistically significantly compared to healthy control (HC) in the IBD group and in the UC group, but although it seemed to be more common than HC in the CD group, it was not statistically significant. Patients with CL in both the IBD group and the HC group were older, but there was no gender difference (p 0.04 and 0.01 for age, 1 and 0.7 for gender, respectively). Conclusion: CL is a common EIM in patients with IBD. In this study, the frequency of CL was found to be increased in IBD compared to HCs.

Keywords

• Inflammatory Bowel Disease
• Cholelithiasis
• Ulcerative Colitis
• Crohn

İnflamatuvar barsak hastalığında kolelitiazis sıklığı

Abstract

Giriş ve Amaç: İnflamatuvar Barsak Hastalığı’nda (İBH) ekstraintestinal bulgulardan (EİM) safra kesesi taşı sıklığı ile ilgili çalışmaların sonuçları tartışmalıdır. Kliniğimizde takip edilen inflamatuvar barsak hastalarında kolelitiazis (KL) sıklığını değerlendirdik. Gereç ve Yöntem: 1 Nisan 2016 ile 1 Aralık 2022 arasında takip edilen hastalar retrospektif olarak değerlendirildi. Bulgular: Çalışmaya 84’ü Ülseratif Kolit (ÜK), 111’i Crohn Hastalığı (CH) olmak üzere 195 İBH tanılı hasta dahil edilmiştir. KL sıklığına bakıldığında tüm İBH grubunda ve ÜK grubunda SK’ye göre KL sıklığı istatistiksel olarak anlamlı artmıştı ancak CH grubunda SK’ye göre daha sık gibi görünse de istatistiksel olarak anlamlı değildi. Hem İBH grubunda hem de SK grubunda KL olan hastalar daha ileri yaşlı idi ancak cinsiyet farkı yoktu (p sırasıyla yaş için 0,04 ve 0,01, cinsiyet için 1 ve 0,7). Sonuç: İBH’de KL sık EIM’dir. Bu çalışmada da sağlıklı kontrollere göre İBH’de KL sıklığı artmış olarak bulunmuştur.

Keywords

• İnflamuvar barsak hastalığı
• kolelitiazis
• ultrasonografi

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