Akromegali ve Gebelik

Year 2017, Volume: 2 Issue: 1, 51 - 53, 10.01.2017

Mehmet KULHAN Nur Gözde KULHAN Ümit NAYKI Cenk NAYKI Paşa ULUĞ

Abstract

Akromegali ve Gebelik

 

Özet (≤250 KELİME)

Akromegali, büyüme hormonunu aşırı sekresyonunun oluşturduğu metabolik etkiler ve hipofiz adenomunun oluşturduğu direkt kitle etkisi ile morbidite ve mortalitede artış ile seyreder. Gonadotropik aks genelde bozuktur ve tedavi edilmeyen kadınlarda gebelik elde etmek zordur. Bu nedenle gebelik ve akromegali nadir bir birlikteliktir ve literatürde oldukça az olgu bildirilmiştir. Dahası, akromegalisi olan gebe kadınlar diabetes mellitus ve kalp damar hastalık prevalansının yüksek olması nedeni ile yüksek riskli gebeliklerdir. Aşağıda transsfenoidal cerrahi ve takiben medikal tedavi sonrası spontan gebelik oluşan bir akromegali olgusu sunulmuştur.

Anahtar
Kelimeler: (3-5 Kelime): Akromegali, Büyüme Hormonu, Gebelik

 

Acromegaly and Pregnancy

 

Abstract (≤250 WORDS)

In acromegaly, the metabolic effects caused by oversecretion of growth hormone and direct mass effect caused by adenoma of the hypophysis lead to increase in morbidity and mortality. Gonotrophic axis is usually defective and pregnancy hardly occurs in nontreated acromegalic women. Thus, pregnancy with acromegaly is uncommon and there are limited reports in literature. Moreover, pregnant women with acromegaly are accepted as high risk pregnancies because of the increased prevelance of diabetes mellitus and cardiovascular diseases. We present a case of acromegalic patient who had spontaneous pregnancy after transsphenoidal surgery followed by medical treatment.

Keywords:
(3-5
Words): Acromegaly, Growth Hormone, Pregnancy.

Keywords

Akromegali, Büyüme Hormonu

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