Evidence-Based Physiotherapy Approaches in Congenital Bleeding Disorders

Year 2023, Volume: 8 Issue: 3, 1053 - 1057, 08.10.2023

Tuğçe Poyraz İşleyen , Ela Tarakcı

https://doi.org/10.61399/ikcusbfd.1189774

Abstract

Inherited bleeding disorders are rare diseases caused by low levels of clotting factors in the blood. Hemophilia A, Hemophilia B, and von Willebrand disease are the bleeding disorders with the highest prevalence. Musculoskeletal bleeding is the most common in hereditary bleeding disorders. These recurrent bleedings can cause degenerations in the joint. Various physiotherapy methods are used to prevent possible bleeding and to relief the symptoms of hemophilic arthropathy. The aim of this review is to provide information about evidence-based physiotherapy approaches in hereditary bleeding disorders

Keywords

Physical therapy, hemophilia, blood coagulation disorders, rehabilitation

Kalıtsal Kanama Bozukluklarında Kanıta Dayalı Fizyoterapi Yaklaşımları

Abstract

Kalıtsal kanama bozuklukları kandaki pıhtılaşma faktörleri eksikliğinden kaynaklanan nadir hastalıklardır. Hemofili A, Hemofili B ve von Willebrand hastalığı prevelansı en fazla olan kanama bozukluklarıdır. Kalıtsal kanama bozukluklarında en sık kas-iskelet sistemi kanamaları gözlenmektedir. Tekrarlayan bu kanamalar eklemde dejenerasyonlara neden olabilmektedir. Muhtemel kanamaların önlenmesi ve hemofilik artropati semptomlarının iyileştirilmesi amacıyla çeşitli fizyoterapi yöntemleri kullanılmaktadır. Bu derlemenin amacı kalıtsal kanama bozukluklarında kanıta dayalı fizyoterapi yaklaşımları hakkında bilgilendirme sağlamaktır.

Keywords

Fizik tedavi, hemofili, kan pıhtılaşma bozuklukları, rehabilitasyon

References

• Mannucci PM, Duga S, Peyvandi F. Recessively inherited coagulation disorders. Blood. 2004;104(5):1243-1252.
• Peyvandi F, Bolton-Maggs PH, Batorova A, De Moerloose P. Rare bleeding disorders. Haemophilia. 2012;18 Suppl 4(SUPPL.4):148-153.
• Kulkarni R, Soucie JM. Pediatric hemophilia: a review. Semin Thromb Hemost. 2011;37(7):737-744.
• Stonebraker JS, Bolton-Maggs PHB, Michael Soucie J, Walker I, Brooker M. A study of variations in the reported haemophilia B prevalence around the world. Haemophilia. 2012;18(3).
• Stonebraker JS, Bolton-Maggs PHB, Michael Soucie J, Walker I, Brooker M. A study of variations in the reported haemophilia A prevalence around the world. Haemophilia. 2010;16(1):20-32.
• Michael Soucie J, Miller CH, Byams VR, et al. Occurrence rates of von Willebrand disease among people receiving care in specialized treatment centres in the United States. Haemophilia. 2021;27(3):445-453.
• Leebeek FWG, Eikenboom JCJ. Von Willebrand’s Disease. Longo DL, ed. N Engl J Med. 2016;375(21):2067-2080.
• Tabibian S, Motlagh H, Naderi M, Dorgalaleh A. Intracranial hemorrhage in congenital bleeding disorders. Blood Coagul Fibrinolysis. 2018;29(1):1-11.
• Gualtierotti R, Solimeno LP, Peyvandi F. Hemophilic arthropathy: Current knowledge and future perspectives. J Thromb Haemost. 2021;19(9):2112-2121.
• Srivastava A, Brewer AK, Mauser-Bunschoten EP, et al. Guidelines for the management of hemophilia. Haemophilia. 2013;19(1).
• van Dijk K, Fischer K, van der Bom JG, Grobbee DE, van den Berg HM. Variability in clinical phenotype of severe haemophilia: the role of the first joint bleed. Haemophilia. 2005;11(5):438-443.
• Rodriguez-Merchan EC. Cartilage damage in the haemophilic joints: pathophysiology, diagnosis and management. Blood Coagul Fibrinolysis. 2012;23(3):179-183.
• Kovacs CS. Hemophilia, low bone mass, and osteopenia/osteoporosis. Transfus Apher Sci. 2008;38(1):33-40.
• Lobet S, Timmer M, Königs C, et al. The Role of Physiotherapy in the New Treatment Landscape for Haemophilia. J Clin Med. 2021;10(13):2822.
• McLaughlin P, Aspdahl M, Matlary RED, et al. Comprehensive care on paper only? The challenge for physiotherapy provision in day to day haemophilia practice. Haemophilia. 2021;27(2):e284-e286.
• Gomis M, González LM, Querol F, Gallach JE, Toca-Herrera JL. Effects of Electrical Stimulation on Muscle Trophism in Patients With Hemophilic Arthropathy. Arch Phys Med Rehabil. 2009;90(11):1924-1930.
• Wagner B, Seuser A, Krüger S, et al. Establishing an online physical exercise program for people with hemophilia. Wien Klin Wochenschr. 2019;131(21):558.
• Blamey G, Forsyth A, Zourikian N, et al. Comprehensive elements of a physiotherapy exercise programme in haemophilia--a global perspective. Haemophilia. 2010;16 Suppl 5(SUPPL. 5):136-145.
• Mulvany R, Zucker-Levin AR, Jeng M, et al. Effects of a 6-Week, individualized, supervised exercise program for people with bleeding disorders and hemophilic arthritis. Phys Ther. 2010;90(4).
• Mazloum V, Rahnama N, Khayambashi K. Effects of therapeutic exercise and hydrotherapy on pain severity and knee range of motion in patients with hemophilia: A randomized controlled trial. Int J Prev Med. 2014;5(1):83-88.
• Feldberg G, Ricciardi JBS, Zorzi AR, Colella MP, Ozelo MC. Aquatic exercise in patients with haemophilia: Electromyographic and functional results from a prospective cohort study. Haemophilia. 2021;27(2):e221-e229.
• Wagner B, Krüger S, Hilberg T, et al. The effect of resistance exercise on strength and safety outcome for people with haemophilia: A systematic review. Haemophilia. 2020;26(2):200.
• Falk B, Portal S, Tiktinsky R, Weinstein Y, Constantini N, Martinowitz U. Anaerobic power and muscle strength in young hemophilia patients. Med Sci Sports Exerc. 2000;32(1):52-57.
• Eid MA, Ibrahim MM, Aly SM. Effect of resistance and aerobic exercises on bone mineral density, muscle strength and functional ability in children with hemophilia. Egypt J Med Hum Genet. 2014;15(2):139-147.
• Calatayud J, Pérez-Alenda S, Carrasco JJ, et al. Upper-Body Exercises With External Resistance Are Well Tolerated and Enhance Muscle Activity in People With Hemophilia. Phys Ther. 2019;99(4):411-419.
• Iorio A, Fabbriciani G, Marcucci M, Brozzetti M, Filipponi P. Bone mineral density in haemophilia patients. A meta-analysis. Thromb Haemost. 2010;103(3):596-603.
• Parhampour B, Dadgoo M, Vasaghi-Gharamaleki B, et al. The effects of six-week resistance, aerobic and combined exercises on the pro-inflammatory and anti-inflammatory markers in overweight patients with moderate haemophilia A: A randomized controlled trial. Haemophilia. 2019;25(4):e257-e266.
• Hilberg T, Hersbsleb M, Puta C, Gabriel HHW, Schramm W. Physical training increases isometric muscular strength and proprioceptive performance in haemophilic subjects. Haemophilia. 2003;9(1):86-93.
• Ravanbod R, Torkaman G, Hedayati M, Nezhad MEZ. Insights into cryotherapy and joint bleeding: cryotherapy and hemophilia. Blood Coagul Fibrinolysis. 2017;28(7):514-520.
• Forsyth AL, Zourikian N, Valentino LA, Rivard GE. The effect of cooling on coagulation and haemostasis: should “Ice” be part of treatment of acute haemarthrosis in haemophilia? Haemophilia. 2012;18(6):843-850.
• Stephensen D, Rodriguez-Merchan EC. Orthopaedic co-morbidities in the elderly haemophilia population: A review. Haemophilia. 2013;19(2):166-173.
• Seuser, A., Wallny, T., Kurth, A., & Berdel P. Conservative treatment in haemophilia - Improving effectivity and establishing standards. Hamostaseologie. 2010;30(1):81-88.
• Seuser A, Berdel P, Oldenburg J. Rehabilitation of synovitis in patients with haemophilia. Haemophilia. 2007;13 Suppl 3(SUPPL.3):26-31.
• Ravanbod R, Torkaman G, Esteki A. Comparison between pulsed ultrasound and low level laser therapy on experimental haemarthrosis. Haemophilia. 2013;19(3):420-425.
• Querol F, Gallach JE, Toca-Herrera JL, Gomis M, Gonzalez LM. Surface electrical stimulation of the quadriceps femoris in patients affected by haemophilia A. Haemophilia. 2006;12(6):629-632.
• Elnaggar RK. Pulsed Nd:YAG laser: effects on pain, postural stability, and weight-bearing pattern in children with hemophilic ankle arthropathy. Lasers Med Sci. 2020;35(5):1075-1083.
• Cuesta-Barriuso R, Gómez-Conesa A, López-Pina JA. Effectiveness of two modalities of physiotherapy in the treatment of haemophilic arthropathy of the ankle: a randomized pilot study. Haemophilia. 2014;20(1).
• Cuesta-Barriuso R, Gómez-Conesa A, López-Pina JA. Manual therapy in the treatment of ankle hemophilic arthropathy. A randomized pilot study. Physiotherapy Theory and Practice. 2014;30(8):534–9.
• Donoso-Úbeda E, Meroño-Gallut J, López-Pina JA, Cuesta-Barriuso R. Effect of manual therapy in patients with hemophilia and ankle arthropathy: a randomized clinical trial. Clin Rehabil. 2020;34(1):111- 119.
• Gönen T, Yakut Y, Akbayram S. The effects of close kinetic chain exercises on proprioception and physical activity level in pediatric patients with hemophilia. Haemophilia. 2022 Nov;28(6):e189-e198.