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Üzümsü Meyvelerde Melatonin İçeriği ve Antioksidan Kapasitenin İncelenmesi

Year 2021, , 820 - 830, 29.11.2021

Yılmaz Uğur

https://doi.org/10.33715/inonusaglik.987625
Cited By: 4

Abstract

Bu çalışmada üzümsü meyvelerden; kurt üzümü (Lycium barbarum), horum dutu (Morus nigra), beyaz dut (Morus alba), böğürtlen (Rubus fructicous L.), mor dut (Morus rubra) ve Bursa siyah dutunda melatonin varlığı durumu HPLC-FD sistemi kullanılarak belirlendi. Tüm örneklerde farklı miktarlarda melatonin tespit edildi. Ayrıca meyve örneklerinde toplam fenolik içerik ve antioksidan kapasite çalışıldı. Antioksidan kapasiteyi belirlemek için DPPH ve ABTS testleri uygulandı. Meyve örneklerindeki melatonin miktarının 123.44 ile1600.48 ng/gFW arasında değiştiği görüldü. Kurt üzümünde (BF1) bulunan melatonin derişiminin diğer üzümsü meyvelere göre daha yüksek olduğu bulundu. En yüksek toplam fenolik içerik ve antioksidan kapasite mor duttan (BF6) sırasıyla 276.83 mg GAE/100 gFW, 452.38 mg TE/100 gFW (DPPH) ve 555.73 mg TE/100 gFW (ABTS) olarak elde edildi. Sonuçlar, toplam fenolik içerik ile antioksidan kapasite arasında pozitif yönde anlamlı bir korelasyon olduğunu göstermektedir.

Keywords

Antioksidan kapasite Üzümsü meyveler Melatonin

References

  • Aguilera, Y., Herrera, T., Benitez, V., Arribas, S. M., Lopez de Pablo, A. L., Esteban, R. M., Martin-Cabrejas, M. A. (2015). Estimation of scavenging capacity of melatonin and other antioxidants: Contribution and evaluation in germinated seeds. Food Chemistry, 170, 203-211.
  • Akbulut, M., Yazıcı, K., Bakoğlu, N., Göksu, B. (2017). Potential and future of small fruits in the Eastern Black Sea Region. Journal of Atatürk Central Horticultural Research Institute, 46 (Special Ed.1), 1-6.
  • Anisimov, V. N., Popovich, I. G., Zabezhinski, M. A., Anisimov, S. V., Vesnushkin, G. M., & Vinogradova, I. A. (2006). Melatonin as antioxidant, geroprotector and anticarcinogen. Biochimica et Biophysica Acta, 1757 (5-6), 573–589.
  • Arnao, M. B. (2014). Phytomelatonin: Discovery, Content, and Role in Plants. Advances in Botany, Article ID 815769, 11 pages.
  • Arnao, M. B., Ruiz, J. H. (2007). Melatonin in plants. Plant Signaling & Behavior, 2 (5), 381-382.
  • Bae, H-S., Kim, H. J., Kang, J. H., Kudo, R., Hosoya, T., Kumazawa, S., …Ahn, M-R. (2015). Anthocyanin profile and antioxidant activity of various berries cultivated in Korea. Natural Product Communications, 10 (6), 963-968.
  • Bae, S. H., Suh, H. J. (2007). Antioxidant activities of five different mulberry cultivars in Korea. Food Science and Technology, 40 (6), 955-962.
  • Chen, G., Huo, Y., Tan, D. X., Liang, Z., Zhang, W., Zhang, Y. (2003). Melatonin in Chinese medicinal herbs. Life Sciences, 73, 19-26.
  • Chen, S. J., Huang, S. H., Chen, J. W., Wang, K. C., Yang, Y. R., Liu, P. F., …Sytwu, H. K. (2016). Melatonin enhances interleukin-10 expression and suppresses chemotaxis to inhibit inflammation in situ and reduce the severity of experimental autoimmune encephalomyelitis. International Immunopharmacology, 31, 169–177.
  • Chen, W., Li, Y., Bao, T., Gowd, V. (2017). Mulberry fruit extract affords protection against ethyl carbamate-induced cytotoxicity and oxidative stress. Hindawi Oxidative Medicine and Cellular Longevity, Article ID 1594963, 12 pages.
  • Ekbul, A. (2004). Dietary polyphenols and cardiovascular system. Türkiye Klinikleri Kardiyoloji Dergisi, 17 (1), 48-54.
  • Engin, S. P., Boz, Y. (2019). The latest developments at berry cultivation of Turkey. IJAAES International Journal of Anatolia Agricultural Engineering, Special Ed.1, 108-115.
  • Ercisli, S., Tosun, M., Duralija, B., Voca, S., Sengul, M., Turan, M. (2010). Phytochemical content of some black (Morus nigra L.) and purple (Morus rubra L.) mulberry genotypes. Food Technology and Biotechnology, 48 (1), 102-106.
  • Ergun, Z., Zarifikhosroshahi, M. (2020). A comparative analysis of oil content and fatty acid in different varieties of Arachis hypogaea L. from Turkey. International Journal of Agriculture Forestry and Life Sciences, 4 (1), 42-47.
  • Gündeşli, M. A. (2020). Determination of Sugar contents, Total Phenol and Antioxidant Activity of various parts ‘Uzun’ pistachio cultivar (Pistacia vera L.). International Journal of Agriculture Environment and Food Sciences, 4(1), 52-58.
  • Gündeşli, M. A., Korkmaz, N., Okatan, V. (2019). Polyphenol content and antioxidant capacity of berries: A review. International Journal of Agriculture, Forestry and Life Sciences, 3 (2), 350-361.
  • Huang, W., Zhang, H., Liu, W., Li, C. (2012). Survey of antioxidant capacity and phenolic composition of blueberry, blackberry, and strawberry in Nanjing. Biomedicine & Biotechnology, 13 (2), 94-102.
  • Hwang, J. Y., Shue, Y. S., Chang, H. M. (2001). Antioxidative activity of roasted and defatted peanut kernels. Food Research International, 34 (7), 639–647.
  • Ionica, M. E., Nour, V., Trandafir, I. (2012). Polyphenols content and antioxidant capacity of goji fruits (Lycium chinense) as affected by the extractıon solvents. South Western Journal of Horticulture, Biology and Environment, 3 (2), 121-129.
  • Kamiloglu, S., Serali, O., Unal, N., Capanoglu, E. (2012). Antioxidant activity and polyphenol composition of black mulberry (Morus nigra L.) products. Journal of Berry Research, 3, 41-51.
  • Kolar, J., Malbeck, J. (2009). Levels of the antioxidant melatonin in fruits of edible berry species. Planta Medica, 75(09), PJ42.
  • Li, F., Li, S., Li, H.B., Deng, G.F., Ling, W.H., Wu, S., …Chen, F. (2013). Antiproliferative activity of peels, pulps and seeds of 61 fruits. Journal of Functional Foods, 5, 1298–1309.
  • Manchester, L. C., Tan, D-X., Reiter, R. J., Park, W., Monis, K., Qi, W. (2000). High levels of melatonin in the seeds of edible plants Possible function in germ tissue protection. Life Sciences, 67, 3023-3029.
  • Meng, X., Li, Y., Li, S., Zhou, Y., Gan, R. Y., Xu, D. P., …Li, H. B. (2017). Dietary sources and bioactivities of melatonin. Nutrients, 9 (4), 367.
  • Mocan, A., Cairone, F., Locatelli, M., Cacciagrano, F., Carradori, S., Vodnar, D. C., …Cesa, S. (2019). Polyphenols from Lycium barbarum (Goji) fruit European cultivars at different maturation steps: extraction, HPLC-DAD analyses, and biological evaluation. Antioxidants, 8, 562.
  • Negro, C., Aprile, A., Bellis, L. D., Miceli, A. (2019). Nutraceutical properties of mulberries grown in Southern Italy (Apulia). Antioxidants, 8, 223.
  • Okatan, V. (2020). Antioxidant properties and phenolic profile of the most widely appreciated cultivated berry species: A comparative study. Folia Horticulturae, 32 (1), 79-85.
  • Oxenkrug, G., Requintina, P., Bachurin, S. (2001). Antioxidant and antiaging activity of N-acetylserotonin and melatonin in the in vivo models. Annals of the New York Academy of Sciences, 939, 190–199.
  • Özgen, M., Serçe, S., Kaya, C. (2009). Phytochemical and antioxidant properties of anthocyanin-rich Morus nigra and Morus rubra fruits. Scientia Horticulturae, 119, 275-279.
  • Pandi-Perumal, S. R., BaHammam, A. S., Brown, G. M., Spence, D. W., Bharti, V. K., Kaur, C., …Cardinali, D. P. (2013). Melatonin antioxidative defense: therapeutical implications for aging and neurodegenerative processes. Neurotoxicity research, 23 (3), 267–300.
  • Pothinuch, P., Tongchitpakdee, S. (2011). Melatonin contents in mulberry (Morus spp.) leaves: Effects of sample preparation, cultivar, leaf age and tea processing. Food Chemistry, 128 (2), 415-419.
  • Rajurkar, N. S., Hande, S. M. (2011). Estimation of phytochemical content and antioxidant activity of some selected traditional Indian medicinal plants. Indian Journal of Pharmaceutical Sciences, 73 (2), 146-151.
  • Shui, G., Leong, L. P. (2006). Residue from star fruit as valuable source for functional food ingredients and antioxidants nutraceuticals. Food Chemistry, 97, 277-284.
  • Wang, H., Cao, G., Prior, R. L. (1996). Total antioxidant capacity of fruits. Journal of Agricultural and Food Chemistry, 44 (3), 701-705.
  • Yan, Y., Shi, Q., Gong, B. (2020). Review of Melatonin in Horticultural Crops, Melatonin - The Hormone of Darkness and its Therapeutic Potential and Perspectives, Marilena Vlachou, IntechOpen. Available from https://www.intechopen.com/chapters/71248. Accessed 19 August 2021.
  • Yen, G. C., Hung, C. Y. (2000). Effects of alkaline and heat treatment on antioxidative activity and total phenolics of extracts from Hsian-tsao (Mesona procumbens Hemsl.). Food Research International, 33, 487-492.
  • Zohar, R., Izhaki, I., Koplovich, A., Ben-Shlomo, R. (2011). Phytomelatonin in the leaves and fruits of wild perennial plants, Phytochemistry Letters, 4, 222-226.
  • Zorzi, M., Gai, F., Medana, C., Aigotti, R., Morello, S., Peiretti, P. G. (2020). Bioactive compounds and antioxidant capacity of small berries. Foods, 9, 623.

INVESTIGATION OF MELATONIN CONTENT AND ANTIOXIDANT CAPACITY IN GRAPE BERRIES

Year 2021, , 820 - 830, 29.11.2021

Yılmaz Uğur

https://doi.org/10.33715/inonusaglik.987625
Cited By: 4

Abstract

In this study, six berry fruits; goji berry/wolfberry (Lycium barbarum), black mulberry (Morus nigra), white mulberry (Morus alba), blackberry (Rubus fructicous L.), purple mulberry (Morus rubra) and Bursa Black mulberry (unknown) were analyzed by HPLC-FD to determine whether they present melatonin. The melatonin was detected different amounts in all samples. Besides, the total phenolic content and antioxidant capacity were studied in all fruit samples. DPPH and ABTS tests were applied to determine the antioxidant capacity. It was observed that the amount of melatonin in the fruit samples varied between 123.44 and 1600.48 ng/gFW. It was found that the concentration of melatonin in goji berry (BF1) was higher than other berry fruits. The highest total phenolic content and antioxidant capacity to were obtained from purple mulberry (BF6) as 276.83 mg GAE/100 gFW, 452.38 mg TE/100 gFW (DPPH) and 555.73 mg TE/100 gFW (ABTS), respectively. Results reveals a significant positive correlation between the total phenolic content with antioxidant capacity.

Keywords

Antioxidant capacity Berry fruits Melatonin

References

  • Aguilera, Y., Herrera, T., Benitez, V., Arribas, S. M., Lopez de Pablo, A. L., Esteban, R. M., Martin-Cabrejas, M. A. (2015). Estimation of scavenging capacity of melatonin and other antioxidants: Contribution and evaluation in germinated seeds. Food Chemistry, 170, 203-211.
  • Akbulut, M., Yazıcı, K., Bakoğlu, N., Göksu, B. (2017). Potential and future of small fruits in the Eastern Black Sea Region. Journal of Atatürk Central Horticultural Research Institute, 46 (Special Ed.1), 1-6.
  • Anisimov, V. N., Popovich, I. G., Zabezhinski, M. A., Anisimov, S. V., Vesnushkin, G. M., & Vinogradova, I. A. (2006). Melatonin as antioxidant, geroprotector and anticarcinogen. Biochimica et Biophysica Acta, 1757 (5-6), 573–589.
  • Arnao, M. B. (2014). Phytomelatonin: Discovery, Content, and Role in Plants. Advances in Botany, Article ID 815769, 11 pages.
  • Arnao, M. B., Ruiz, J. H. (2007). Melatonin in plants. Plant Signaling & Behavior, 2 (5), 381-382.
  • Bae, H-S., Kim, H. J., Kang, J. H., Kudo, R., Hosoya, T., Kumazawa, S., …Ahn, M-R. (2015). Anthocyanin profile and antioxidant activity of various berries cultivated in Korea. Natural Product Communications, 10 (6), 963-968.
  • Bae, S. H., Suh, H. J. (2007). Antioxidant activities of five different mulberry cultivars in Korea. Food Science and Technology, 40 (6), 955-962.
  • Chen, G., Huo, Y., Tan, D. X., Liang, Z., Zhang, W., Zhang, Y. (2003). Melatonin in Chinese medicinal herbs. Life Sciences, 73, 19-26.
  • Chen, S. J., Huang, S. H., Chen, J. W., Wang, K. C., Yang, Y. R., Liu, P. F., …Sytwu, H. K. (2016). Melatonin enhances interleukin-10 expression and suppresses chemotaxis to inhibit inflammation in situ and reduce the severity of experimental autoimmune encephalomyelitis. International Immunopharmacology, 31, 169–177.
  • Chen, W., Li, Y., Bao, T., Gowd, V. (2017). Mulberry fruit extract affords protection against ethyl carbamate-induced cytotoxicity and oxidative stress. Hindawi Oxidative Medicine and Cellular Longevity, Article ID 1594963, 12 pages.
  • Ekbul, A. (2004). Dietary polyphenols and cardiovascular system. Türkiye Klinikleri Kardiyoloji Dergisi, 17 (1), 48-54.
  • Engin, S. P., Boz, Y. (2019). The latest developments at berry cultivation of Turkey. IJAAES International Journal of Anatolia Agricultural Engineering, Special Ed.1, 108-115.
  • Ercisli, S., Tosun, M., Duralija, B., Voca, S., Sengul, M., Turan, M. (2010). Phytochemical content of some black (Morus nigra L.) and purple (Morus rubra L.) mulberry genotypes. Food Technology and Biotechnology, 48 (1), 102-106.
  • Ergun, Z., Zarifikhosroshahi, M. (2020). A comparative analysis of oil content and fatty acid in different varieties of Arachis hypogaea L. from Turkey. International Journal of Agriculture Forestry and Life Sciences, 4 (1), 42-47.
  • Gündeşli, M. A. (2020). Determination of Sugar contents, Total Phenol and Antioxidant Activity of various parts ‘Uzun’ pistachio cultivar (Pistacia vera L.). International Journal of Agriculture Environment and Food Sciences, 4(1), 52-58.
  • Gündeşli, M. A., Korkmaz, N., Okatan, V. (2019). Polyphenol content and antioxidant capacity of berries: A review. International Journal of Agriculture, Forestry and Life Sciences, 3 (2), 350-361.
  • Huang, W., Zhang, H., Liu, W., Li, C. (2012). Survey of antioxidant capacity and phenolic composition of blueberry, blackberry, and strawberry in Nanjing. Biomedicine & Biotechnology, 13 (2), 94-102.
  • Hwang, J. Y., Shue, Y. S., Chang, H. M. (2001). Antioxidative activity of roasted and defatted peanut kernels. Food Research International, 34 (7), 639–647.
  • Ionica, M. E., Nour, V., Trandafir, I. (2012). Polyphenols content and antioxidant capacity of goji fruits (Lycium chinense) as affected by the extractıon solvents. South Western Journal of Horticulture, Biology and Environment, 3 (2), 121-129.
  • Kamiloglu, S., Serali, O., Unal, N., Capanoglu, E. (2012). Antioxidant activity and polyphenol composition of black mulberry (Morus nigra L.) products. Journal of Berry Research, 3, 41-51.
  • Kolar, J., Malbeck, J. (2009). Levels of the antioxidant melatonin in fruits of edible berry species. Planta Medica, 75(09), PJ42.
  • Li, F., Li, S., Li, H.B., Deng, G.F., Ling, W.H., Wu, S., …Chen, F. (2013). Antiproliferative activity of peels, pulps and seeds of 61 fruits. Journal of Functional Foods, 5, 1298–1309.
  • Manchester, L. C., Tan, D-X., Reiter, R. J., Park, W., Monis, K., Qi, W. (2000). High levels of melatonin in the seeds of edible plants Possible function in germ tissue protection. Life Sciences, 67, 3023-3029.
  • Meng, X., Li, Y., Li, S., Zhou, Y., Gan, R. Y., Xu, D. P., …Li, H. B. (2017). Dietary sources and bioactivities of melatonin. Nutrients, 9 (4), 367.
  • Mocan, A., Cairone, F., Locatelli, M., Cacciagrano, F., Carradori, S., Vodnar, D. C., …Cesa, S. (2019). Polyphenols from Lycium barbarum (Goji) fruit European cultivars at different maturation steps: extraction, HPLC-DAD analyses, and biological evaluation. Antioxidants, 8, 562.
  • Negro, C., Aprile, A., Bellis, L. D., Miceli, A. (2019). Nutraceutical properties of mulberries grown in Southern Italy (Apulia). Antioxidants, 8, 223.
  • Okatan, V. (2020). Antioxidant properties and phenolic profile of the most widely appreciated cultivated berry species: A comparative study. Folia Horticulturae, 32 (1), 79-85.
  • Oxenkrug, G., Requintina, P., Bachurin, S. (2001). Antioxidant and antiaging activity of N-acetylserotonin and melatonin in the in vivo models. Annals of the New York Academy of Sciences, 939, 190–199.
  • Özgen, M., Serçe, S., Kaya, C. (2009). Phytochemical and antioxidant properties of anthocyanin-rich Morus nigra and Morus rubra fruits. Scientia Horticulturae, 119, 275-279.
  • Pandi-Perumal, S. R., BaHammam, A. S., Brown, G. M., Spence, D. W., Bharti, V. K., Kaur, C., …Cardinali, D. P. (2013). Melatonin antioxidative defense: therapeutical implications for aging and neurodegenerative processes. Neurotoxicity research, 23 (3), 267–300.
  • Pothinuch, P., Tongchitpakdee, S. (2011). Melatonin contents in mulberry (Morus spp.) leaves: Effects of sample preparation, cultivar, leaf age and tea processing. Food Chemistry, 128 (2), 415-419.
  • Rajurkar, N. S., Hande, S. M. (2011). Estimation of phytochemical content and antioxidant activity of some selected traditional Indian medicinal plants. Indian Journal of Pharmaceutical Sciences, 73 (2), 146-151.
  • Shui, G., Leong, L. P. (2006). Residue from star fruit as valuable source for functional food ingredients and antioxidants nutraceuticals. Food Chemistry, 97, 277-284.
  • Wang, H., Cao, G., Prior, R. L. (1996). Total antioxidant capacity of fruits. Journal of Agricultural and Food Chemistry, 44 (3), 701-705.
  • Yan, Y., Shi, Q., Gong, B. (2020). Review of Melatonin in Horticultural Crops, Melatonin - The Hormone of Darkness and its Therapeutic Potential and Perspectives, Marilena Vlachou, IntechOpen. Available from https://www.intechopen.com/chapters/71248. Accessed 19 August 2021.
  • Yen, G. C., Hung, C. Y. (2000). Effects of alkaline and heat treatment on antioxidative activity and total phenolics of extracts from Hsian-tsao (Mesona procumbens Hemsl.). Food Research International, 33, 487-492.
  • Zohar, R., Izhaki, I., Koplovich, A., Ben-Shlomo, R. (2011). Phytomelatonin in the leaves and fruits of wild perennial plants, Phytochemistry Letters, 4, 222-226.
  • Zorzi, M., Gai, F., Medana, C., Aigotti, R., Morello, S., Peiretti, P. G. (2020). Bioactive compounds and antioxidant capacity of small berries. Foods, 9, 623.
There are 38 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Araştırma Makalesi
Authors

Yılmaz Uğur 0000-0002-9040-4249

Publication Date November 29, 2021
Submission Date August 26, 2021
Acceptance Date October 6, 2021
Published in Issue Year 2021

Cite

APA Uğur, Y. (2021). INVESTIGATION OF MELATONIN CONTENT AND ANTIOXIDANT CAPACITY IN GRAPE BERRIES. İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi, 9(3), 820-830. https://doi.org/10.33715/inonusaglik.987625

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