Abstract
The use of real blood for in vitro experiments in bioengineering studies is unlikely not possible due to reasons as; obtaining, storing, manipulating, being required in large quantities, changing of the structure when exposed to air and toxicity. Therefore, it is an important issue to investigate the fluids that will be used instead of blood in the in vitro experiments. These fluids are expected to exhibit rheological properties similar to human blood. However, as blood rheology is extremely complex, it is difficult to develop blood analogue fluids that meet all rheological properties of blood. Since all properties of blood cannot be achieved at the same time with a single analogue fluid, depending on the characteristics of the study in laboratory environment different blood analogues are selected to replace blood. In most studies, analogues exhibiting the closest behavior to the rheological properties of the blood come to the fore with the addition of Xanthan Gum (XG) to the compositions prepared for these blood analogs. In this study; blood analogue fluids that can replace blood in in vitro conditions have been investigated, the main characteristics of these analogs have been presented with tables and suggestions have been made.