Evaluation of Children with Infantile Wheezing at The Age of Six: A New Asthma Predictive Index

Year 2018, Volume: 2018 Issue: 1, 84 - 95, 24.05.2018

Ramazan Keçeci İsmail Reisli

Abstract

Background: Recurrent wheezing is a common problem in young children. It is difficult to diagnose real asthma in children under 6 years of age because of different phenotypes of wheezing related disorders in this age group.
Patients and Method: This study was performed in the outpatient clinic of Pediatric Allergy and Immunology Department. This study includes 208 children who visited at least three times during the first three years of their lives with the complaints of wheezing attacks. Those who visited the department with the diseases such as congenital malformation, gastro esophageal reflux, tracheobronchial fistula, aspiration syndrome, heart failure, cystic fibrosis and immunodeficiency were eliminated and excluded from the study.
Findings: Transient early wheezing 107 (51,4%), non atopic wheezing 28 (13,5%), atopic wheezing 73 (35,1%) have been detected. Sixty five (31,3%) of the children were females and 143 (68,7%) were males. After the separate and together evaluation of the risk factors we have developed an asthma prediction index. The values of the index have been found as it is written below. The sensitivity 83%, specificity 90,7%, positive predictive value 89,2%, negative predictive value was 85,2%.
Conclusion: It might be possible to distinguish which of the children who comes to the department with the complaints of recurrent wheezing might suffer from asthma by using the asthma prediction index. It might also be possible to change the natural course of the disease by developing early intervene strategies
Keywords: wheezing, child, wheezing phenotypes, asthma predictive index.

Keywords

wheezing, child, wheezing phenotypes, asthma predictive index

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