Research Article

Balloon angioplasty performed with coronary balloons in newborns with severe coarctation of aorta: a single center experience

Volume: 17 Number: 57 April 16, 2026

Balloon angioplasty performed with coronary balloons in newborns with severe coarctation of aorta: a single center experience

Abstract

Objective: Critical coarctation of the aorta (CoA) may cause severe left ventricular dysfunction and systemic hypoperfusion in the neonatal period. Surgical treatment in the neonatal period is superior to balloon angioplasty due to lower recoarctation and reintervention rates. However, surgical mortality increases in hemodynamically compromised patients. This has generated interest in emergency palliative balloon angioplasty as a bridge to surgery. The present study reports outcomes of emergency palliative balloon angioplasty performed with coronary balloons due to resource limitations, including the absence of neonatal-specific balloons and inconsistent access to pediatric cardiac centers. Method: Records of all newborns diagnosed with critical CoA [w11.1][OÇ1.2]and undergoing coronary balloon angioplasty were retrospectively reviewed. Results: The study included 14 critical neonates who underwent balloon angioplasty with coronary balloons. After the procedure, 13 of 14 patients with successful balloon use had left ventricular functions to return normalize within the first 24 hours. The diameter of the narrowest site increased from 1.71 to 4.34 mm (p<0.001), the peak-to-peak gradient decreased from 63.5±19 to 20.5±15.1 mmHg (p=0.002), ejection fraction increased from 42.3±9.1% to 68.3±4.7% (p<0.001). Circulatory disorder regressed and laboratory tests improved. After a successful balloon, 4 patients discharged from the hospital without surgery. In 5 patients, surgery was performed in better condition and all of them were discharged and no one developed recoarctation. One patient had second balloon angioplasty performed. Conclusion: Coronary balloons can be used safely with palliative aims in newborns with high surgical mortality risk as a bridge to surgery.

Keywords

References

  1. Meliota G, Lombardi M, Zaza P, Tagliente MR, Vairo U. Balloon angioplasty of aortic coarctation in critically ill newborns using axillary artery access. Ann Pediatr Cardiol. 2020;13(1):67-71. https://doi.org/10.4103/apc.APC_2_19
  2. Hoffman JI, Kaplan S. The incidence of congenital heart disease. J Am Coll Cardiol. 2002;39(12):1890-900. https://doi.org/10.1016/s0735-1097(02)01886-7
  3. He L, Liu F, Wu L, Qi CH, Zhang LF, Huang GY. Percutaneous balloon angioplasty for severe native aortic coarctation in young infants less than 6 months: medium- to long-term follow-up. Chin Med J (Engl). 2015;128(8):1021-5. https://doi.org/10.4103/0366-6999.155069
  4. Wu Y, Jin X, Kuang H, Lv T, Li Y, Zhou Y, Wu C. Is balloon angioplasty superior to surgery in the treatment of paediatric native coarctation of the aorta: a systematic review and meta-analysis. Interact Cardiovasc Thorac Surg. 2019;28(2):291-300. https://doi.org/10.1093/icvts/ivy224
  5. Hoffman JI. The challenge in diagnosing coarctation of the aorta. Cardiovasc J Afr. 2018;29(4):252-255. https://doi.org/10.5830/CVJA-2017-053
  6. Singer MI, Rowen M, Dorsey TJ. Transluminal aortic balloon angioplasty for coarctation of the aorta in the newborn. Am Heart J. 1982;103(1):131-2. https://doi.org/10.1016/0002-8703(82)90539-7
  7. Bouzguenda I, Marini D, Ou P, Boudjemline Y, Bonnet D, Agnoletti G. Percutaneous treatment of neonatal aortic coarctation presenting with severe left ventricular dysfunction as a bridge to surgery. Cardiol Young. 2009;19(3):244-51. https://doi.org/10.1017/S1047951109003837
  8. Ghaderian M, Sabri MR, Ahmadi A, Bayat S. Our first experience in stenting of coarctation of aorta in infants and small children; A case series study. ARYA Atheroscler. 2019;15(2):93-98. https://doi.org/10.22122/arya.v15i2.1961

Details

Primary Language

English

Subjects

Paediatrics (Other)

Journal Section

Research Article

Publication Date

April 16, 2026

Submission Date

March 26, 2025

Acceptance Date

January 27, 2026

Published in Issue

Year 2026 Volume: 17 Number: 57

APA
Yılmaz, N., Akbaş, Y., El, Ç., & Çalışkan, O. F. (2026). Balloon angioplasty performed with coronary balloons in newborns with severe coarctation of aorta: a single center experience. Interdisciplinary Medical Journal, 17(57), 43-51. https://doi.org/10.17944/interdiscip.1666358
AMA
1.Yılmaz N, Akbaş Y, El Ç, Çalışkan OF. Balloon angioplasty performed with coronary balloons in newborns with severe coarctation of aorta: a single center experience. Interdiscip Med J. 2026;17(57):43-51. doi:10.17944/interdiscip.1666358
Chicago
Yılmaz, Nuh, Yılmaz Akbaş, Çiğdem El, and Osman Fırat Çalışkan. 2026. “Balloon Angioplasty Performed With Coronary Balloons in Newborns With Severe Coarctation of Aorta: A Single Center Experience”. Interdisciplinary Medical Journal 17 (57): 43-51. https://doi.org/10.17944/interdiscip.1666358.
EndNote
Yılmaz N, Akbaş Y, El Ç, Çalışkan OF (April 1, 2026) Balloon angioplasty performed with coronary balloons in newborns with severe coarctation of aorta: a single center experience. Interdisciplinary Medical Journal 17 57 43–51.
IEEE
[1]N. Yılmaz, Y. Akbaş, Ç. El, and O. F. Çalışkan, “Balloon angioplasty performed with coronary balloons in newborns with severe coarctation of aorta: a single center experience”, Interdiscip Med J, vol. 17, no. 57, pp. 43–51, Apr. 2026, doi: 10.17944/interdiscip.1666358.
ISNAD
Yılmaz, Nuh - Akbaş, Yılmaz - El, Çiğdem - Çalışkan, Osman Fırat. “Balloon Angioplasty Performed With Coronary Balloons in Newborns With Severe Coarctation of Aorta: A Single Center Experience”. Interdisciplinary Medical Journal 17/57 (April 1, 2026): 43-51. https://doi.org/10.17944/interdiscip.1666358.
JAMA
1.Yılmaz N, Akbaş Y, El Ç, Çalışkan OF. Balloon angioplasty performed with coronary balloons in newborns with severe coarctation of aorta: a single center experience. Interdiscip Med J. 2026;17:43–51.
MLA
Yılmaz, Nuh, et al. “Balloon Angioplasty Performed With Coronary Balloons in Newborns With Severe Coarctation of Aorta: A Single Center Experience”. Interdisciplinary Medical Journal, vol. 17, no. 57, Apr. 2026, pp. 43-51, doi:10.17944/interdiscip.1666358.
Vancouver
1.Nuh Yılmaz, Yılmaz Akbaş, Çiğdem El, Osman Fırat Çalışkan. Balloon angioplasty performed with coronary balloons in newborns with severe coarctation of aorta: a single center experience. Interdiscip Med J. 2026 Apr. 1;17(57):43-51. doi:10.17944/interdiscip.1666358