The role of cervical lordosis angle in the differential diagnosis of chest pain after Exercise electrocardiography test

Emre Melik Faideci; Zeynep Dağlar; Sinan Güzel; Mustafa Bestami Maraşlı; Tolga Türkmen; Mehmet Dokur; Murat Ziyrek

doi:10.17944/interdiscip.1708493

The role of cervical lordosis angle in the differential diagnosis of chest pain after Exercise electrocardiography test

Abstract

Objectives: The exercise electrocardiography test (EET) is extensively utilized for diagnosing stable angina pectoris (SAP). Nonetheless, differential diagnosis may prove difficult in instances of chest discomfort absent ischemic indicators. The loss of cervical lordosis (LCL) and several cervical diseases may be implicated in non-cardiac chest discomfort. Methods: This retrospective study evaluated 216 patients who experienced chest pain during EET without ischemic ECG changes and underwent invasive coronary angiography (ICA) and cervical spine radiography (CSR). Among them, 18 patients with significant cervical pathologies apart from LCL were excluded from angle measurements. Cervical lordosis angle (CLA) was measured only in patients without additional cervical pathology. Results: CLA was significantly lower in the CAD (–) group compared to the CAD (+) group (13.97° ± 8.82 vs. 29.20° ± 7.58; p<0.001). An increase in CLA independently predicted the presence of CAD (OR: 1.197; 95% CI: 1.135–1.264; p<0.001). Using a cut-off value of 20.5°, CAD could be predicted with 78.3% sensitivity and 79.6% specificity (AUC: 0.892). However, a decrease in CLA was insufficient to exclude cardiac etiology in chest pain. Conclusion: The measurement of CLA post-cervical spine assessment may facilitate clinical decision-making in the differential diagnosis of chest pain subsequent to EET and assist in directing secondary testing procedures.

Keywords

References

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Details

Primary Language

English

Subjects

Cardiology, Cardiovascular Medicine and Haematology (Other)

Journal Section

Research Article

Authors

Emre Melik Faideci ^*
0000-0002-0272-9271
Türkiye

Zeynep Dağlar
0000-0001-5144-9666
Türkiye

Sinan Güzel
0000-0001-6564-2360
Türkiye

Mustafa Bestami Maraşlı
0009-0006-8951-6063
Türkiye

Tolga Türkmen
0000-0002-0113-2617
Türkiye

Mehmet Dokur
0000-0003-2119-3801
Türkiye

Murat Ziyrek
0000-0003-4032-7561
Türkiye

Publication Date

December 16, 2025

Submission Date

May 29, 2025

Acceptance Date

October 12, 2025

Published in Issue

Year 2025 Volume: 16 Number: 56

DOI

https://doi.org/10.17944/interdiscip.1708493

IZ

https://izlik.org/JA96CS43NZ

Cite

RIS / Bibtex

APA

Faideci, E. M., Dağlar, Z., Güzel, S., Maraşlı, M. B., Türkmen, T., Dokur, M., & Ziyrek, M. (2025). The role of cervical lordosis angle in the differential diagnosis of chest pain after Exercise electrocardiography test. Interdisciplinary Medical Journal, 16(56), 168-174. https://doi.org/10.17944/interdiscip.1708493

AMA

1.Faideci EM, Dağlar Z, Güzel S, et al. The role of cervical lordosis angle in the differential diagnosis of chest pain after Exercise electrocardiography test. Interdiscip Med J. 2025;16(56):168-174. doi:10.17944/interdiscip.1708493

Chicago

Faideci, Emre Melik, Zeynep Dağlar, Sinan Güzel, et al. 2025. “The Role of Cervical Lordosis Angle in the Differential Diagnosis of Chest Pain After Exercise Electrocardiography Test”. Interdisciplinary Medical Journal 16 (56): 168-74. https://doi.org/10.17944/interdiscip.1708493.

EndNote

Faideci EM, Dağlar Z, Güzel S, Maraşlı MB, Türkmen T, Dokur M, Ziyrek M (December 1, 2025) The role of cervical lordosis angle in the differential diagnosis of chest pain after Exercise electrocardiography test. Interdisciplinary Medical Journal 16 56 168–174.

IEEE

[1]E. M. Faideci et al., “The role of cervical lordosis angle in the differential diagnosis of chest pain after Exercise electrocardiography test”, Interdiscip Med J, vol. 16, no. 56, pp. 168–174, Dec. 2025, doi: 10.17944/interdiscip.1708493.

ISNAD

Faideci, Emre Melik - Dağlar, Zeynep - Güzel, Sinan - Maraşlı, Mustafa Bestami - Türkmen, Tolga - Dokur, Mehmet - Ziyrek, Murat. “The Role of Cervical Lordosis Angle in the Differential Diagnosis of Chest Pain After Exercise Electrocardiography Test”. Interdisciplinary Medical Journal 16/56 (December 1, 2025): 168-174. https://doi.org/10.17944/interdiscip.1708493.

JAMA

1.Faideci EM, Dağlar Z, Güzel S, Maraşlı MB, Türkmen T, Dokur M, Ziyrek M. The role of cervical lordosis angle in the differential diagnosis of chest pain after Exercise electrocardiography test. Interdiscip Med J. 2025;16:168–174.

MLA

Faideci, Emre Melik, et al. “The Role of Cervical Lordosis Angle in the Differential Diagnosis of Chest Pain After Exercise Electrocardiography Test”. Interdisciplinary Medical Journal, vol. 16, no. 56, Dec. 2025, pp. 168-74, doi:10.17944/interdiscip.1708493.

Vancouver

1.Emre Melik Faideci, Zeynep Dağlar, Sinan Güzel, Mustafa Bestami Maraşlı, Tolga Türkmen, Mehmet Dokur, Murat Ziyrek. The role of cervical lordosis angle in the differential diagnosis of chest pain after Exercise electrocardiography test. Interdiscip Med J. 2025 Dec. 1;16(56):168-74. doi:10.17944/interdiscip.1708493