Asthma evaluation of risk factors in atopic patients in the Hatay Region

Kadir Burak Akgün; Sahinur Aycan Alkan; Ömer Atar

doi:10.17944/interdiscip.1900993

Asthma evaluation of risk factors in atopic patients in the Hatay Region

Abstract

Objective: This study investigated the role of systemic inflammatory indices and specific aeroallergen sensitizations in predicting asthma among patients with allergic rhinitis (AR) and asthma, within the United Airway Disease (UAD) framework. Method: A retrospective study was conducted including 575 patients who underwent skin prick testing (SPT). Patients were categorized into four groups: healthy controls, AR only, allergic asthma, and non-allergic asthma. Demographics, SPT results, and inflammatory indices were compared. Independent risk factors for asthma were analyzed via multivariate logistic regression. Results: No statistically significant differences in eosinophil levels or systemic inflammatory indices were detected among the four phenotypes (p>0.05). However, the median age and the proportion of females were observed to be higher in asthmatic patients. In the multivariate analysis, increasing age (OR: 1.019), being female sex (OR: 1.515), tree pollen (OR: 1.953), and cockroach (OR: 1.618) sensitizations were identified as independent risk factors for asthma. House dust mite sensitization was lost its significance in the multivariate model. Conclusion: The predictive value of systemic inflammatory indices in distinguishing asthma phenotypes is considered low in stable atopic patients. Tree pollen and cockroach sensitizations, rather than house dust mites, were proven as the strongest independent determinants of asthma development among the studied population in the Mediterranean climate of Hatay, influenced by climate change and precipitation.

Keywords

Ethical Statement

Ethical permission for this study was obtained from the Hatay Mustafa Kemal University Non-Interventional Research Ethics Committee on 25.02.2026 with the number 05, and the rules of the Helsinki Declaration were followed to conduct this study.

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Details

Primary Language

English

Subjects

Chest Diseases

Journal Section

Research Article

Authors

Kadir Burak Akgün ^*
0000-0002-3017-1025
Türkiye

Sahinur Aycan Alkan
0000-0001-8233-2639
Türkiye

Ömer Atar
0009-0000-2830-9489
Türkiye

Publication Date

August 23, 2026

Submission Date

March 5, 2026

Acceptance Date

May 4, 2026

Published in Issue

Year 2026 Volume: 17 Number: 58

DOI

https://doi.org/10.17944/interdiscip.1900993

IZ

https://izlik.org/JA86CM97NA

Cite

RIS / Bibtex

APA

Akgün, K. B., Alkan, S. A., & Atar, Ö. (2026). Asthma evaluation of risk factors in atopic patients in the Hatay Region. Interdisciplinary Medical Journal, 17(58), 129-137. https://doi.org/10.17944/interdiscip.1900993

AMA

1.Akgün KB, Alkan SA, Atar Ö. Asthma evaluation of risk factors in atopic patients in the Hatay Region. Interdiscip Med J. 2026;17(58):129-137. doi:10.17944/interdiscip.1900993

Chicago

Akgün, Kadir Burak, Sahinur Aycan Alkan, and Ömer Atar. 2026. “Asthma Evaluation of Risk Factors in Atopic Patients in the Hatay Region”. Interdisciplinary Medical Journal 17 (58): 129-37. https://doi.org/10.17944/interdiscip.1900993.

EndNote

Akgün KB, Alkan SA, Atar Ö (August 1, 2026) Asthma evaluation of risk factors in atopic patients in the Hatay Region. Interdisciplinary Medical Journal 17 58 129–137.

IEEE

[1]K. B. Akgün, S. A. Alkan, and Ö. Atar, “Asthma evaluation of risk factors in atopic patients in the Hatay Region”, Interdiscip Med J, vol. 17, no. 58, pp. 129–137, Aug. 2026, doi: 10.17944/interdiscip.1900993.

ISNAD

Akgün, Kadir Burak - Alkan, Sahinur Aycan - Atar, Ömer. “Asthma Evaluation of Risk Factors in Atopic Patients in the Hatay Region”. Interdisciplinary Medical Journal 17/58 (August 1, 2026): 129-137. https://doi.org/10.17944/interdiscip.1900993.

JAMA

1.Akgün KB, Alkan SA, Atar Ö. Asthma evaluation of risk factors in atopic patients in the Hatay Region. Interdiscip Med J. 2026;17:129–137.

MLA

Akgün, Kadir Burak, et al. “Asthma Evaluation of Risk Factors in Atopic Patients in the Hatay Region”. Interdisciplinary Medical Journal, vol. 17, no. 58, Aug. 2026, pp. 129-37, doi:10.17944/interdiscip.1900993.

Vancouver

1.Kadir Burak Akgün, Sahinur Aycan Alkan, Ömer Atar. Asthma evaluation of risk factors in atopic patients in the Hatay Region. Interdiscip Med J. 2026 Aug. 1;17(58):129-37. doi:10.17944/interdiscip.1900993