Abstract
In this case, vaginal leiomyosarcoma subsequent to pyometra is described in a 10-year old Labrador Retriever bitch. Bloody, malodorous discharge related to pyometra was present from the vagina for 4 months. Ovariohysterectomy recommended but the owner refused the operation. Three weeks after the first examination a rapidly growing mass and a bulge were noticed in the vagina. The dog underwent ovariohysterectomy and a biopsy was taken from the mass at the vagina during this surgery and submitted to pathology laboratory. It was diagnosed as leiomyosarcoma in histopathological and immunohistochemical examinations. After the mass extirpated surgically the recurrence was occurred in one and a half months later. The bitch’s general condition deteriorated rapidly and she died. Because of the late arrival of the patient to our clinic and in order to the request of the owner, treatment protocols could not be able to applied properly so the case was failed. The aim of this case is to transfer the surgical approaches to these kinds of reproductive pathologies to the literature. It is concluded that these kinds of pathologies should be treated immediately.
Keywords
References
- Behzatoğlu, K., Bahadır, B., Inhan, G., Altug, M., 200 Primary vaginal leiomyosarcoma in pregnancy. Gynecologic Oncology 91, 627-629. Cooper, B.J., Valentine, B.A., 2002. Tumours of Muscle. In: Meuten, D.J. (Ed), Tumours in Domestic Animals. Blackwell Publishing Company, USA, pp. 319-363.
- Enginler, S.O., Gündüz, M.C., Sabuncu, A., Senünver, A., Yıldız, F., Arun, S.S., 2011. Vaginal leiomyosarcoma in A holstein cow. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 17 (2), 325-327.
- Ferreira, M.I.C., Pinto, L.F., 2008. Homeopathic treatment of vaginal leiomyoma in adog: case report. International Journal of High Dilution Research 7 (24), 152-158.
- Fırat, I., Haktanır-Yatkın, D., Sontas, B.H., Ekici, H., 2007. Vulvar leiomyosarcoma in a cat. Journal of Feline Medicine and Surgery 9, 4354
- Hossein, N., Iraj, K., Bonyadian, M., 2009. Vaginal leiomyosarcoma in a pregnant dairy cow. Journal of Comparative Pathology 141 (4), 301. Hulland, T.J., 1990. Tumours of the muscle. In: Moulton, J. E. (Ed.): Tumours of domestic animals, University of California Press, Berkeley, pp. 75-88, Miller, M.A., Ramos-Vara, J.A., Dıckerson, M.F., Johnson, G.C., Pace, L.W., Kreeger, J.M., Turnquıst, S.E., Turk, J.R., 2003. Uterine neoplasia in 13 cats. Journal of Veterinary Diagnostic Investigation 15, 515-522.
- Smith, F.O., 2006. Canine Pyometra. Theriogenology 66, 610-612.
- Thacher, C., Bradley, R.L., 1983. Vulvar and vaginal tumours in the dog. A retrospective study. Journal of the American Veterinary Medical Association 183, 690-692.
- Tsioli, V.G., Gouletsou, P.G., Loukopoulos, P., Zavlarıs, M., Galatos, A.D., 2011. Uterine leiomyosarcoma and pyometra in a dog. Journal of Small Animal Practice 52, 121-124.
- Vemireddi, V., Langohr, I.M., Thacker, H.L., 2007. Polypoid uterine leiomyosarcomas in a sheep. Journal of the Veterinary Diagnostic. Investigation 19, 309-312.
- Whitney, K.M., Valentine, B.A., Schlafer, D.H., 2000. Caprine genital leiomyosarcoma. Veterinary Pathology 37, 89-94.
- Yeruham, I., Perl, S., Orgad, U., Yakobson, B., 19 Tumours of the vulva and vagina in cattle- A 10 - year survey. The Veterinary Journal 158, 237-239.
Abstract
ABSTRACT
In this case, vaginal leiomyosarcoma subsequent to pyometra is described in a 10-year old Labrador Retriever bitch. Bloody, malodorous discharge related to pyometra was present from the vagina for 4 months. Ovariohysterectomy recommended but the owner refused the operation. Three weeks after the first examination a rapidly growing mass and a bulge were noticed in the vagina. The dog underwent ovariohysterectomy and a biopsy was taken from the mass at the vagina during this surgery and submitted to pathology laboratory. It was diagnosed as leiomyosarcoma in histopathological and immunohistochemical examinations. After the mass extirpated surgically the recurrence was occurred in one and a half months later. The bitch's general condition deteriorated rapidly and she died. Because of the late arrival of the patient to our clinic and in order to the request of the owner, treatment protocols could not be able to applied properly so the case was failed. The aim of this case is to transfer the surgical approaches to these kinds of reproductive pathologies to the literature. It is concluded that these kinds of pathologies should be treated immediately.
Key Words: Bitch, leiomyosarcoma, vagina, pyometra
ÖZET
BİR DİŞİ LABRADOR KÖPEKTE PYOMETRAYI TAKİBEN GÖRÜLEN VAGİNAL LEİOMYOSARKOMA
Bu olguda 10 yaşlı Labrador dişi bir köpekte pyometrayı takiben görülen vaginal leiomyosarkoma anlatıldı. Köpekte 4 aydır devam eden pyometraya bağlı kanlı, pis kokulu vaginal akıntı vardı. Köpeğe ovariohisterektomi önerildi fakat hasta sahibi bu öneriyi reddetti. İlk muayeneden 3 hafta sonra hızlıca büyüyen, çıkıntı yapan bir kitle vaginada fark edildi. Köpeğe ovariohisterektomi yapıldı ve bu esnada vaginadaki kitleden de biyopsi alınarak patoloji laboratuarına yollandı. Histopatolojik ve immunohistokimyasal değerlendirme sonucunda kitle leiomyosarkoma olarak saptandı. Kitlenin ameliyatla uzaklaştırılmasından 1,5 ay sonra nüks gözlendi. Köpeğin genel durumu hızlıca kötüledi. Köpeğin kliniğimize geç getirilmesinden ve hasta sahibinin isteği doğrultusunda, tedavi protokollerinin düzenli olarak uygulanamamasından dolayı köpeği kaybettik. Bu olgunun amacı bu tarz reprodüktif patolojilerin cerrahi yaklaşımlarının yazına aktarılmasıdır. Sonuç olarak, bu tarz patolojilerin hızlıca tedavi edilmesi gerekliliği saptandı.
Anahtar Kelimeler: Dişi köpek, leiomyosarkoma, vagina, pyometra
Keywords
References
- Behzatoğlu, K., Bahadır, B., Inhan, G., Altug, M., 200 Primary vaginal leiomyosarcoma in pregnancy. Gynecologic Oncology 91, 627-629. Cooper, B.J., Valentine, B.A., 2002. Tumours of Muscle. In: Meuten, D.J. (Ed), Tumours in Domestic Animals. Blackwell Publishing Company, USA, pp. 319-363.
- Enginler, S.O., Gündüz, M.C., Sabuncu, A., Senünver, A., Yıldız, F., Arun, S.S., 2011. Vaginal leiomyosarcoma in A holstein cow. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 17 (2), 325-327.
- Ferreira, M.I.C., Pinto, L.F., 2008. Homeopathic treatment of vaginal leiomyoma in adog: case report. International Journal of High Dilution Research 7 (24), 152-158.
- Fırat, I., Haktanır-Yatkın, D., Sontas, B.H., Ekici, H., 2007. Vulvar leiomyosarcoma in a cat. Journal of Feline Medicine and Surgery 9, 4354
- Hossein, N., Iraj, K., Bonyadian, M., 2009. Vaginal leiomyosarcoma in a pregnant dairy cow. Journal of Comparative Pathology 141 (4), 301. Hulland, T.J., 1990. Tumours of the muscle. In: Moulton, J. E. (Ed.): Tumours of domestic animals, University of California Press, Berkeley, pp. 75-88, Miller, M.A., Ramos-Vara, J.A., Dıckerson, M.F., Johnson, G.C., Pace, L.W., Kreeger, J.M., Turnquıst, S.E., Turk, J.R., 2003. Uterine neoplasia in 13 cats. Journal of Veterinary Diagnostic Investigation 15, 515-522.
- Smith, F.O., 2006. Canine Pyometra. Theriogenology 66, 610-612.
- Thacher, C., Bradley, R.L., 1983. Vulvar and vaginal tumours in the dog. A retrospective study. Journal of the American Veterinary Medical Association 183, 690-692.
- Tsioli, V.G., Gouletsou, P.G., Loukopoulos, P., Zavlarıs, M., Galatos, A.D., 2011. Uterine leiomyosarcoma and pyometra in a dog. Journal of Small Animal Practice 52, 121-124.
- Vemireddi, V., Langohr, I.M., Thacker, H.L., 2007. Polypoid uterine leiomyosarcomas in a sheep. Journal of the Veterinary Diagnostic. Investigation 19, 309-312.
- Whitney, K.M., Valentine, B.A., Schlafer, D.H., 2000. Caprine genital leiomyosarcoma. Veterinary Pathology 37, 89-94.
- Yeruham, I., Perl, S., Orgad, U., Yakobson, B., 19 Tumours of the vulva and vagina in cattle- A 10 - year survey. The Veterinary Journal 158, 237-239.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | January 3, 2014 |
| Published in Issue | Year 2014 Volume: 40 Issue: 1 |