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Comparison of mfERG with VEP in NAION Patients and Healthy People

Year 2018, Volume: 1 Issue: 1, 50 - 54, 30.12.2018

Abstract

References

  • 1.Clinical application of mfERG/VEP in assessing superior altitudinal hemifield loss. Chan HH, Ng FY, Chu PH. Clin Exp Optom. 2005 Jul;88(4):253-7.2.The detection of small simulated field defects using multifocal VEPs. Chan HL, Tam WK, Chen CL, Ng NC .Ophthalmic Physiol Opt 2003; 23: 205-212.3.Clinical value of electrophysiology in determining the diagnosis of visual dysfunction in neuro-ophthalmology patients. Yap GH, Chen LY, Png R, Loo JL, Tow S, Mathur R, Chia A. Doc Ophthalmol. 2015 Dec;131(3):189-96. doi: 10.1007/s10633-015-9515-9. Epub 2015 Oct 16.4. Multifocal electroretinography and optical coherence tomography in two patients with solar retinopathy.Schatz P1, Eriksson U, Ponjavic V, Andréasson S. Acta Ophthalmol Scand. 2004 Aug;82(4):476-85.Multifocal visual evoked potential, multifocal electroretinography, and optical coherence tomography in the diagnosis of subclinical loss of vision.Hedges TR 3rd, Quireza ML. Ophthalmol Clin North Am. 2004 Mar;17(1):89-105.6.Electrophysiology in ophthalmology .Meigen T. Ophthalmologe. 2015 Jun;112(6):533-44; quiz 545-6. doi: 10.1007/s00347-015-0055-1.7.Recording of both VEP and multifocal ERG for evaluation of unexplained visual loss electrophysiology in unexplained visual loss. Renner AB, Kellner U, Tillack H, Kraus H, Foerster MH. Doc Ophthalmol. 2005 Nov;111(3):149-57. Epub 2006 Mar 6.8. Multifocal ERG in chloroquine retinopathy: regional variance of retinal dysfunction.Kellner U1, Kraus H, Foerster MH. Graefes Arch Clin Exp Ophthalmol. 2000 Jan;238(1):94-7.9. Pattern electroretinography (PERG) and an integrated approach to visual pathway diagnosis.Holder GE. Prog Retin Eye Res. 2001 Jul;20(4):531-61.10. Electrophysiological assessment of optic nerve disease. Holder GE. Eye (Lond). 2004 Nov;18(11):1133-43.11. Assessing retinal function with the multifocal technique.Hood DC. Prog Retin Eye Res. 2000 Sep;19(5):607-46.12. Atypical multifocal ERG responses in patients with diseases affecting the photoreceptors.Greenstein VC1, Holopigian K, Seiple W, Carr RE, Hood DC. Vision Res. 2004 Nov;44(25):2867-74.

Comparison of mfERG with VEP in NAION Patients and Healthy People

Year 2018, Volume: 1 Issue: 1, 50 - 54, 30.12.2018

Abstract

Purpose: Comparison of mfERG (multifocal electroretinography)with VEP(vizual evoked potential )in NAION(Nonarteritic ischemic optic neuropathy) patients and healthy people

 

Materials and methods: 44 NAION patients were included in the study.The patients  were 23 woman, 21  male. The average age was  60-83  in NAION group.The patients underwent mfERG and VEP. 35 healthy people formed the control group. In the control group was 19 woman, 17  male. The average age was 57-89 in control group.

 

Results: Mean VEP amplitude 1.89  * 0, 95mV and latency 123,6 * 18,70 msec in NAION  group . In healthy group VEP amplitude was 4.92  * 1, 02mV and latency  was 103,01 * 7.02 msec. There was no obvious pathology in mfERG in patients with NAION and in the control group.

 

Conclusion: In NAION patients, significant changes can be seen in VEP amplitude and VEP latency. This was also found in our work.Ganglion cell and optic disc damage does not change in the mfERG , so abnormal mfERG is probably a reporter of an external retinal lesion.

 













Key words: mfERG, VEP, NAION

References

  • 1.Clinical application of mfERG/VEP in assessing superior altitudinal hemifield loss. Chan HH, Ng FY, Chu PH. Clin Exp Optom. 2005 Jul;88(4):253-7.2.The detection of small simulated field defects using multifocal VEPs. Chan HL, Tam WK, Chen CL, Ng NC .Ophthalmic Physiol Opt 2003; 23: 205-212.3.Clinical value of electrophysiology in determining the diagnosis of visual dysfunction in neuro-ophthalmology patients. Yap GH, Chen LY, Png R, Loo JL, Tow S, Mathur R, Chia A. Doc Ophthalmol. 2015 Dec;131(3):189-96. doi: 10.1007/s10633-015-9515-9. Epub 2015 Oct 16.4. Multifocal electroretinography and optical coherence tomography in two patients with solar retinopathy.Schatz P1, Eriksson U, Ponjavic V, Andréasson S. Acta Ophthalmol Scand. 2004 Aug;82(4):476-85.Multifocal visual evoked potential, multifocal electroretinography, and optical coherence tomography in the diagnosis of subclinical loss of vision.Hedges TR 3rd, Quireza ML. Ophthalmol Clin North Am. 2004 Mar;17(1):89-105.6.Electrophysiology in ophthalmology .Meigen T. Ophthalmologe. 2015 Jun;112(6):533-44; quiz 545-6. doi: 10.1007/s00347-015-0055-1.7.Recording of both VEP and multifocal ERG for evaluation of unexplained visual loss electrophysiology in unexplained visual loss. Renner AB, Kellner U, Tillack H, Kraus H, Foerster MH. Doc Ophthalmol. 2005 Nov;111(3):149-57. Epub 2006 Mar 6.8. Multifocal ERG in chloroquine retinopathy: regional variance of retinal dysfunction.Kellner U1, Kraus H, Foerster MH. Graefes Arch Clin Exp Ophthalmol. 2000 Jan;238(1):94-7.9. Pattern electroretinography (PERG) and an integrated approach to visual pathway diagnosis.Holder GE. Prog Retin Eye Res. 2001 Jul;20(4):531-61.10. Electrophysiological assessment of optic nerve disease. Holder GE. Eye (Lond). 2004 Nov;18(11):1133-43.11. Assessing retinal function with the multifocal technique.Hood DC. Prog Retin Eye Res. 2000 Sep;19(5):607-46.12. Atypical multifocal ERG responses in patients with diseases affecting the photoreceptors.Greenstein VC1, Holopigian K, Seiple W, Carr RE, Hood DC. Vision Res. 2004 Nov;44(25):2867-74.
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Details

Primary Language English
Subjects Health Care Administration
Journal Section Articles
Authors

Hande Hüsniye Telek 0000-0002-5922-3319

Publication Date December 30, 2018
Submission Date November 7, 2018
Acceptance Date December 28, 2018
Published in Issue Year 2018 Volume: 1 Issue: 1

Cite

APA Telek, H. H. (2018). Comparison of mfERG with VEP in NAION Patients and Healthy People. İzlek Akademik Dergi, 1(1), 50-54.


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