Increased Apoptosis in the Liver of Chalcalburnus tarichi Exposed to Sublethal Concentrations of Methyl Parathion

Volume: 8 Number: 1 February 1, 2014
  • Ertuğrul Kankaya
  • Burak Kaptaner
EN

Increased Apoptosis in the Liver of Chalcalburnus tarichi Exposed to Sublethal Concentrations of Methyl Parathion

Abstract

In the present study, the effect of methyl parathion (MP), an extensively used organophosphorus insecticide in agriculture, on liver apoptosis in Chalcalburnus tarichi, an endemic carp species of the Lake Van Basin of Turkey, was investigated. For this purpose, fish were exposed to sublethal concentrations (1.47, 3.0, and 6.11 mg/L) of MP for 30 days under semistatic conditions. Following exposure, sections taken from the liver were stained using the terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling method for the examination of apoptosis, and then apoptotic hepatocytes were evaluated as the apoptotic index (AI). According to the results, the AI was significantly enhanced at MP concentrations of 3.0 and 6.11 mg/L. In conclusion, the present study indicates that MP has apoptosis-inducing potential in the liver of C. tarichi and MP-dependent hepatotoxicity causally related to the increase in the apoptosis

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Primary Language

English

Subjects

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Journal Section

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Authors

Ertuğrul Kankaya This is me

Burak Kaptaner This is me

Publication Date

February 1, 2014

Submission Date

February 1, 2014

Acceptance Date

-

Published in Issue

Year 2014 Volume: 8 Number: 1

APA
Kankaya, E., & Kaptaner, B. (2014). Increased Apoptosis in the Liver of Chalcalburnus tarichi Exposed to Sublethal Concentrations of Methyl Parathion. Journal of Applied Biological Sciences, 8(1), 45-48. https://izlik.org/JA57JD38FJ
AMA
1.Kankaya E, Kaptaner B. Increased Apoptosis in the Liver of Chalcalburnus tarichi Exposed to Sublethal Concentrations of Methyl Parathion. J.appl.biol.sci. 2014;8(1):45-48. https://izlik.org/JA57JD38FJ
Chicago
Kankaya, Ertuğrul, and Burak Kaptaner. 2014. “Increased Apoptosis in the Liver of Chalcalburnus Tarichi Exposed to Sublethal Concentrations of Methyl Parathion”. Journal of Applied Biological Sciences 8 (1): 45-48. https://izlik.org/JA57JD38FJ.
EndNote
Kankaya E, Kaptaner B (February 1, 2014) Increased Apoptosis in the Liver of Chalcalburnus tarichi Exposed to Sublethal Concentrations of Methyl Parathion. Journal of Applied Biological Sciences 8 1 45–48.
IEEE
[1]E. Kankaya and B. Kaptaner, “Increased Apoptosis in the Liver of Chalcalburnus tarichi Exposed to Sublethal Concentrations of Methyl Parathion”, J.appl.biol.sci., vol. 8, no. 1, pp. 45–48, Feb. 2014, [Online]. Available: https://izlik.org/JA57JD38FJ
ISNAD
Kankaya, Ertuğrul - Kaptaner, Burak. “Increased Apoptosis in the Liver of Chalcalburnus Tarichi Exposed to Sublethal Concentrations of Methyl Parathion”. Journal of Applied Biological Sciences 8/1 (February 1, 2014): 45-48. https://izlik.org/JA57JD38FJ.
JAMA
1.Kankaya E, Kaptaner B. Increased Apoptosis in the Liver of Chalcalburnus tarichi Exposed to Sublethal Concentrations of Methyl Parathion. J.appl.biol.sci. 2014;8:45–48.
MLA
Kankaya, Ertuğrul, and Burak Kaptaner. “Increased Apoptosis in the Liver of Chalcalburnus Tarichi Exposed to Sublethal Concentrations of Methyl Parathion”. Journal of Applied Biological Sciences, vol. 8, no. 1, Feb. 2014, pp. 45-48, https://izlik.org/JA57JD38FJ.
Vancouver
1.Ertuğrul Kankaya, Burak Kaptaner. Increased Apoptosis in the Liver of Chalcalburnus tarichi Exposed to Sublethal Concentrations of Methyl Parathion. J.appl.biol.sci. [Internet]. 2014 Feb. 1;8(1):45-8. Available from: https://izlik.org/JA57JD38FJ