The Effects of Nonylphenol on Gamete Physiology in Bovine

Volume: 8 Number: 2 July 1, 2014
  • Selcen Süheyla Ergün
  • Burcu Üstüner
  • Selim Alçay
  • Hakan Sağırkaya
  • Cevdet Uğuz
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Journal of Applied Biological Sciences
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The Effects of Nonylphenol on Gamete Physiology in Bovine

Abstract

Alkylphenol ethoxylates (APEOs) are used as non-ionic surfactants in variety of industrial, agricultiral and domestic products such as pesticides, detergents, paints and cosmetics. Therefore, these compounds can reach to humanbeing through foodchains. These endocrine disurpters also called Xenoestogen have estrogenic, carsinogenic and toxic effects. Nonylphenol (NP) exerts its estrogenic effects by binding to estrogen receptors. NP causes morphological and functional alterations in male and female genital tract and mammary glands. These alterations may induce infertility, mammary and prostate cancer. Therefore, the main purpose of this study is to determine the adverse effects of NP on sperm and oocytes. The effects environmentally relevant NP concentrations such as 0.01, 0.1, 1, 10 and 100 µg NP/ml were employed. NP mediated abnormalities in sperm DNA and oocyte maturation were inviestigated. Tunel assay was performed to determine the adverse effects of NP on sperm DNA, whereas the effects of NP on oocyte maturation in TCM-199 were tested. The present study demonstrated that 100 µg NP/ml concentration induced apoptosis by causing DNA breaks in bovine sperm cells. This study also showed that 100 µg NP/ml concentrations inhibits oocyte maturation. It is concluded that NP have adverse effects on the integrity of sperm DNA and oocyte maturation

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Primary Language

English

Subjects

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Journal Section

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Authors

Selcen Süheyla Ergün This is me

Burcu Üstüner This is me

Selim Alçay This is me

Hakan Sağırkaya This is me

Cevdet Uğuz This is me

Publication Date

July 1, 2014

Submission Date

July 1, 2014

Acceptance Date

-

Published in Issue

Year 2014 Volume: 8 Number: 2

IZ

https://izlik.org/JA28LX75XK

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RIS / Bibtex
APA
Ergün, S. S., Üstüner, B., Alçay, S., Sağırkaya, H., & Uğuz, C. (2014). The Effects of Nonylphenol on Gamete Physiology in Bovine. Journal of Applied Biological Sciences, 8(2), 32-38. https://izlik.org/JA28LX75XK
AMA
1.Ergün SS, Üstüner B, Alçay S, Sağırkaya H, Uğuz C. The Effects of Nonylphenol on Gamete Physiology in Bovine. J.appl.biol.sci. 2014;8(2):32-38. https://izlik.org/JA28LX75XK
Chicago
Ergün, Selcen Süheyla, Burcu Üstüner, Selim Alçay, Hakan Sağırkaya, and Cevdet Uğuz. 2014. “The Effects of Nonylphenol on Gamete Physiology in Bovine”. Journal of Applied Biological Sciences 8 (2): 32-38. https://izlik.org/JA28LX75XK.
EndNote
Ergün SS, Üstüner B, Alçay S, Sağırkaya H, Uğuz C (July 1, 2014) The Effects of Nonylphenol on Gamete Physiology in Bovine. Journal of Applied Biological Sciences 8 2 32–38.
IEEE
[1]S. S. Ergün, B. Üstüner, S. Alçay, H. Sağırkaya, and C. Uğuz, “The Effects of Nonylphenol on Gamete Physiology in Bovine”, J.appl.biol.sci., vol. 8, no. 2, pp. 32–38, July 2014, [Online]. Available: https://izlik.org/JA28LX75XK
ISNAD
Ergün, Selcen Süheyla - Üstüner, Burcu - Alçay, Selim - Sağırkaya, Hakan - Uğuz, Cevdet. “The Effects of Nonylphenol on Gamete Physiology in Bovine”. Journal of Applied Biological Sciences 8/2 (July 1, 2014): 32-38. https://izlik.org/JA28LX75XK.
JAMA
1.Ergün SS, Üstüner B, Alçay S, Sağırkaya H, Uğuz C. The Effects of Nonylphenol on Gamete Physiology in Bovine. J.appl.biol.sci. 2014;8:32–38.
MLA
Ergün, Selcen Süheyla, et al. “The Effects of Nonylphenol on Gamete Physiology in Bovine”. Journal of Applied Biological Sciences, vol. 8, no. 2, July 2014, pp. 32-38, https://izlik.org/JA28LX75XK.
Vancouver
1.Selcen Süheyla Ergün, Burcu Üstüner, Selim Alçay, Hakan Sağırkaya, Cevdet Uğuz. The Effects of Nonylphenol on Gamete Physiology in Bovine. J.appl.biol.sci. [Internet]. 2014 Jul. 1;8(2):32-8. Available from: https://izlik.org/JA28LX75XK