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Year 2007, Volume: 1 Issue: 1, 51 - 56, 01.02.2007

Abstract

Damage caused by free oxygen radicals is quite important in ischemia/reperfusion (I/R). Therefore, our study focuses on
the effects of Aspirin and Vitamin E on the activity changes in erythrocyte radical scavenging enzymes in superoxide
dismutase (SOD), catalase (CAT) and glutathione peroxidase (Gpx) activities following liver ischemia/reperfusion in rats.
Winstar albino male rats were divided into six groups as sham, isotonic saline solvent Aspirin, Vitamin E solvent corn oil
injected control groups and Aspirin, Vitamin E and Aspirin+Vitamin E injected test groups. Rats subjected to ischemia were
then grouped and exposed to reperfusion at the 0th, 2nd, 8th and 24th hours. After reperfusion, blood samples were taken via a
dispossible injector from the heart at these hours and the enzyme activities were studied in erythrocyte fractions. Enzyme
activity changes were seen during reperfusion periods, particularly the 2nd hour of reperfusion more striking than in ischemia
period. When Aspirin and Vitamin E were given separately caused enzyme activity changes but these changes more
remarkable when Aspirin and Vitamin E given together. Considering these results, Aspirin and Vitamin E may be suggested
to prevent post-ischemic damage owing to their potential therapeutic effects.

The Effects of Aspirin and Vitamin E on Blood Antioxidant Enzymes of Rats during Experimental Liver Ischemia-Reperfusion

Year 2007, Volume: 1 Issue: 1, 51 - 56, 01.02.2007

Abstract

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Details

Other ID JA56EJ75DA
Journal Section Research Article
Authors

Birsen KILIÇOĞLU Aydın This is me

Zafer Eren This is me

Publication Date February 1, 2007
Published in Issue Year 2007 Volume: 1 Issue: 1

Cite

APA Aydın, B. K., & Eren, Z. (2007). The Effects of Aspirin and Vitamin E on Blood Antioxidant Enzymes of Rats during Experimental Liver Ischemia-Reperfusion. Journal of Applied Biological Sciences, 1(1), 51-56.
AMA Aydın BK, Eren Z. The Effects of Aspirin and Vitamin E on Blood Antioxidant Enzymes of Rats during Experimental Liver Ischemia-Reperfusion. J.appl.biol.sci. February 2007;1(1):51-56.
Chicago Aydın, Birsen KILIÇOĞLU, and Zafer Eren. “The Effects of Aspirin and Vitamin E on Blood Antioxidant Enzymes of Rats During Experimental Liver Ischemia-Reperfusion”. Journal of Applied Biological Sciences 1, no. 1 (February 2007): 51-56.
EndNote Aydın BK, Eren Z (February 1, 2007) The Effects of Aspirin and Vitamin E on Blood Antioxidant Enzymes of Rats during Experimental Liver Ischemia-Reperfusion. Journal of Applied Biological Sciences 1 1 51–56.
IEEE B. K. Aydın and Z. Eren, “The Effects of Aspirin and Vitamin E on Blood Antioxidant Enzymes of Rats during Experimental Liver Ischemia-Reperfusion”, J.appl.biol.sci., vol. 1, no. 1, pp. 51–56, 2007.
ISNAD Aydın, Birsen KILIÇOĞLU - Eren, Zafer. “The Effects of Aspirin and Vitamin E on Blood Antioxidant Enzymes of Rats During Experimental Liver Ischemia-Reperfusion”. Journal of Applied Biological Sciences 1/1 (February 2007), 51-56.
JAMA Aydın BK, Eren Z. The Effects of Aspirin and Vitamin E on Blood Antioxidant Enzymes of Rats during Experimental Liver Ischemia-Reperfusion. J.appl.biol.sci. 2007;1:51–56.
MLA Aydın, Birsen KILIÇOĞLU and Zafer Eren. “The Effects of Aspirin and Vitamin E on Blood Antioxidant Enzymes of Rats During Experimental Liver Ischemia-Reperfusion”. Journal of Applied Biological Sciences, vol. 1, no. 1, 2007, pp. 51-56.
Vancouver Aydın BK, Eren Z. The Effects of Aspirin and Vitamin E on Blood Antioxidant Enzymes of Rats during Experimental Liver Ischemia-Reperfusion. J.appl.biol.sci. 2007;1(1):51-6.