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Identification and Characterization of Rat ETV6 Gene by Using Bioinformatics Tools

Year 2007, Volume: 1 Issue: 1, 19 - 23, 01.02.2007

Lokman Varıslı Osman Cen

Abstract

The products of ETS (erythroblast transformation specific domain) family genes are essential for a variety of developmental processes. This group of genes is frequently involved in leukemia and sarcoma as the result of specific chromosomal translocations. The ETV6 (ETS variant gene 6) gene, also called Tel or Tel1, is a member of the ETS family transcriptional regulators. Using in silico bioinformatic tools, we identified and characterized the rat ETV6 gene in this study. It has 8 exons and is located on the rat genomic contig NW_047696 of the rat chromosome 4. Its protein product has a predicted nuclear localization signal, one SAM_PNT (SAM-Pointed domain), and one ETS conserved domain. It has high homology to those of other vertebrate species. This is the first report on identification and characterization of the rat ETV6 gene

Keywords

Bioinformatics comparative genomics ETV6 rat genome

Year 2007, Volume: 1 Issue: 1, 19 - 23, 01.02.2007

Lokman Varıslı Osman Cen

Abstract

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Details

Other ID JA89YK42KE
Journal Section Research Article
Authors

Lokman Varıslı This is me

Osman Cen This is me

Publication Date February 1, 2007
Published in Issue Year 2007 Volume: 1 Issue: 1

Cite

APA Varıslı, L., & Cen, O. (2007). Identification and Characterization of Rat ETV6 Gene by Using Bioinformatics Tools. Journal of Applied Biological Sciences, 1(1), 19-23.
AMA Varıslı L, Cen O. Identification and Characterization of Rat ETV6 Gene by Using Bioinformatics Tools. J.appl.biol.sci. February 2007;1(1):19-23.
Chicago Varıslı, Lokman, and Osman Cen. “Identification and Characterization of Rat ETV6 Gene by Using Bioinformatics Tools”. Journal of Applied Biological Sciences 1, no. 1 (February 2007): 19-23.
EndNote Varıslı L, Cen O (February 1, 2007) Identification and Characterization of Rat ETV6 Gene by Using Bioinformatics Tools. Journal of Applied Biological Sciences 1 1 19–23.
IEEE L. Varıslı and O. Cen, “Identification and Characterization of Rat ETV6 Gene by Using Bioinformatics Tools”, J.appl.biol.sci., vol. 1, no. 1, pp. 19–23, 2007.
ISNAD Varıslı, Lokman - Cen, Osman. “Identification and Characterization of Rat ETV6 Gene by Using Bioinformatics Tools”. Journal of Applied Biological Sciences 1/1 (February 2007), 19-23.
JAMA Varıslı L, Cen O. Identification and Characterization of Rat ETV6 Gene by Using Bioinformatics Tools. J.appl.biol.sci. 2007;1:19–23.
MLA Varıslı, Lokman and Osman Cen. “Identification and Characterization of Rat ETV6 Gene by Using Bioinformatics Tools”. Journal of Applied Biological Sciences, vol. 1, no. 1, 2007, pp. 19-23.
Vancouver Varıslı L, Cen O. Identification and Characterization of Rat ETV6 Gene by Using Bioinformatics Tools. J.appl.biol.sci. 2007;1(1):19-23.