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Anti-hyperlipidaemic Effects of an Essential Oil of Melissa officinalis. L in Cholesterol-fed Rabbits

Year 2010, Volume: 4 Issue: 1, 17 - 22, 01.02.2010

Abstract

The aim of this study was to investigate the effects of an essential oil (EO) of a traditional herb; Melissa officinalis (MO), on the lipid profile of rabbits fed a cholesterol-rich diet (HC). Twenty rabbits were divided into four groups (n=5 for each): Normal control (NC) which fed a standard diet and three cholesterol-fed groups: HC, HC + 1% MO, and HC + 3% MO groups which received 0%, 1% , and 3% EO, respectively for four weeks. Blood samples were collected on day 0 and then at weeks 1, 2, 3, and 4 to determine the levels of total serum cholesterol (TC), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), very low density lipoprotein-cholesterol (VLDL-C), triglycerides (TGs) and atherogenic index (AI). There were no significant differences in body weight gain and food intake in all groups. The HC apparently raised the TC, LDL-C, VLDL-C, HDL-C and TGs without significant accrual effect on AI. In comparison to NC group, EO in both HC + 1% MO and HC + 3% MO groups significantly decreased serum lipid and lipoprotein level whereas no significant effect on AI was observed. It can be concluded that EO extracted from MO leaves contributes to a lipid-lowering action in cholesterol-fed rabbits

Year 2010, Volume: 4 Issue: 1, 17 - 22, 01.02.2010

Abstract

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Details

Other ID JA49UN46VB
Journal Section Research Article
Authors

Isaac Karımı This is me

Hossein Hayatgheybı This is me

Mostafa Razmjo This is me

Másume Yousefı This is me

Amir Dadyan This is me

Mohammadmehdi Hadıpour This is me

Publication Date February 1, 2010
Published in Issue Year 2010 Volume: 4 Issue: 1

Cite

APA Karımı, I., Hayatgheybı, H., Razmjo, M., Yousefı, M., et al. (2010). Anti-hyperlipidaemic Effects of an Essential Oil of Melissa officinalis. L in Cholesterol-fed Rabbits. Journal of Applied Biological Sciences, 4(1), 17-22.
AMA Karımı I, Hayatgheybı H, Razmjo M, Yousefı M, Dadyan A, Hadıpour M. Anti-hyperlipidaemic Effects of an Essential Oil of Melissa officinalis. L in Cholesterol-fed Rabbits. J.appl.biol.sci. February 2010;4(1):17-22.
Chicago Karımı, Isaac, Hossein Hayatgheybı, Mostafa Razmjo, Másume Yousefı, Amir Dadyan, and Mohammadmehdi Hadıpour. “Anti-Hyperlipidaemic Effects of an Essential Oil of Melissa Officinalis. L in Cholesterol-Fed Rabbits”. Journal of Applied Biological Sciences 4, no. 1 (February 2010): 17-22.
EndNote Karımı I, Hayatgheybı H, Razmjo M, Yousefı M, Dadyan A, Hadıpour M (February 1, 2010) Anti-hyperlipidaemic Effects of an Essential Oil of Melissa officinalis. L in Cholesterol-fed Rabbits. Journal of Applied Biological Sciences 4 1 17–22.
IEEE I. Karımı, H. Hayatgheybı, M. Razmjo, M. Yousefı, A. Dadyan, and M. Hadıpour, “Anti-hyperlipidaemic Effects of an Essential Oil of Melissa officinalis. L in Cholesterol-fed Rabbits”, J.appl.biol.sci., vol. 4, no. 1, pp. 17–22, 2010.
ISNAD Karımı, Isaac et al. “Anti-Hyperlipidaemic Effects of an Essential Oil of Melissa Officinalis. L in Cholesterol-Fed Rabbits”. Journal of Applied Biological Sciences 4/1 (February 2010), 17-22.
JAMA Karımı I, Hayatgheybı H, Razmjo M, Yousefı M, Dadyan A, Hadıpour M. Anti-hyperlipidaemic Effects of an Essential Oil of Melissa officinalis. L in Cholesterol-fed Rabbits. J.appl.biol.sci. 2010;4:17–22.
MLA Karımı, Isaac et al. “Anti-Hyperlipidaemic Effects of an Essential Oil of Melissa Officinalis. L in Cholesterol-Fed Rabbits”. Journal of Applied Biological Sciences, vol. 4, no. 1, 2010, pp. 17-22.
Vancouver Karımı I, Hayatgheybı H, Razmjo M, Yousefı M, Dadyan A, Hadıpour M. Anti-hyperlipidaemic Effects of an Essential Oil of Melissa officinalis. L in Cholesterol-fed Rabbits. J.appl.biol.sci. 2010;4(1):17-22.