Diversity of Lactococcus garvieae by Genomic Approaches

Salih Kumru

doi:10.35229/jaes.894280

TR EN

Lactococcus garvieae'nin Genomik Yaklaşımlarla Çeşitliliği

Öz

Lactococcus garvieae is the Gram-positive cocci bacteria known as the causative agent of infectious systemic disease. It causes fatal hemorrhagic septicemia in mainly cultured fish species, animals, and humans worldwide. Comparative genome analyses provide valuable information about genome identification and unique genomic features. In this study, the available L. garvieae genomes are evaluated by comparative genomics approaches. The results indicated that there are four distinct genetic groups of L. garvieae based on the Average Nucleotide Identity (ANI) value. The phylogenetic tree was produced using 16S rRNA sequence has similar genetic variances with the publicly available L. garvieae genome data on NCBI and supports the ANI value. In silico analysis of antimicrobial resistance revealed that each L. garvieae genome groups have unique antimicrobial resistance class genes, even though, all genomes have a common antibiotic-resistant class. Analyzing results of the antimicrobial resistance supports the L. garvieae genetic variations. This extensively comparative approach will provide new insights into the understanding of L. garvieae genomic diversity and antimicrobial resistance.

Anahtar Kelimeler

Antibiyotik direnclilik , Karşılaştırmalı genomik , Lactococcus garvieae , Filogenetik ağaç

Diversity of Lactococcus garvieae by Genomic Approaches

Abstract

Lactococcus garvieae is the Gram-positive cocci bacteria known as the causative agent of infectious systemic disease. It causes fatal hemorrhagic septicemia in mainly cultured fish species, animals, and humans worldwide. Comparative genome analyses provide valuable information about genome identification and unique genomic features. In this study, the available L. garvieae genomes are evaluated by comparative genomics approaches. The results indicated that there are four distinct genetic groups of L. garvieae based on the Average Nucleotide Identity (ANI) value. The phylogenetic tree was produced using 16S rRNA sequence has similar genetic variances with the publicly available L. garvieae genome data on NCBI and supports the ANI value. In silico analysis of antimicrobial resistance revealed that each L. garvieae genome groups have unique antimicrobial resistance class genes, even though, all genomes have a common antibiotic-resistant class. Analyzing results of the antimicrobial resistance supports the L. garvieae genetic variations. This extensively comparative approach will provide new insights into the understanding of L. garvieae genomic diversity and antimicrobial resistance.

Keywords

Antibiotic resistance , Comparative genomics , Phylogenetic tree, , Lactococcus garvieae

References

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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Salih Kumru ^*
0000-0002-2309-3110
Türkiye

Publication Date

December 31, 2021

Submission Date

July 28, 2021

Acceptance Date

November 4, 2021

Published in Issue

Year 2021 Volume: 6 Number: 4

DOI

https://doi.org/10.35229/jaes.894280

IZ

https://izlik.org/JA67BW72MM

APA

Kumru, S. (2021). Diversity of Lactococcus garvieae by Genomic Approaches. Journal of Anatolian Environmental and Animal Sciences, 6(4), 506-513. https://doi.org/10.35229/jaes.894280

Cited By

Hastalıklı Gökkuşağı Alabalığından İzole Edilen Lactococcus spp. Suşlarının Tanımlanması ve Antimikrobiyal Duyarlılığının Belirlenmesi

Journal of Anatolian Environmental and Animal Sciences

https://doi.org/10.35229/jaes.1513751

EBSCOHost Scilit CABI

JAES/AAS-Journal of Anatolian Environmental and Animal Sciences/Anatolian Academic Sciences&Anadolu Çevre ve Hayvancılık Dergisi/Anadolu Akademik Bilimler-AÇEH/AAS