Araştırma Makalesi

Diversity of Lactococcus garvieae by Genomic Approaches

Cilt: 6 Sayı: 4 31 Aralık 2021

Salih Kumru ^*

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Journal of Anatolian Environmental and Animal Sciences

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Lactococcus garvieae'nin Genomik Yaklaşımlarla Çeşitliliği

Öz

Lactococcus garvieae is the Gram-positive cocci bacteria known as the causative agent of infectious systemic disease. It causes fatal hemorrhagic septicemia in mainly cultured fish species, animals, and humans worldwide. Comparative genome analyses provide valuable information about genome identification and unique genomic features. In this study, the available L. garvieae genomes are evaluated by comparative genomics approaches. The results indicated that there are four distinct genetic groups of L. garvieae based on the Average Nucleotide Identity (ANI) value. The phylogenetic tree was produced using 16S rRNA sequence has similar genetic variances with the publicly available L. garvieae genome data on NCBI and supports the ANI value. In silico analysis of antimicrobial resistance revealed that each L. garvieae genome groups have unique antimicrobial resistance class genes, even though, all genomes have a common antibiotic-resistant class. Analyzing results of the antimicrobial resistance supports the L. garvieae genetic variations. This extensively comparative approach will provide new insights into the understanding of L. garvieae genomic diversity and antimicrobial resistance.

Anahtar Kelimeler

Antibiyotik direnclilik , Karşılaştırmalı genomik , Lactococcus garvieae , Filogenetik ağaç

Diversity of Lactococcus garvieae by Genomic Approaches

Abstract

Lactococcus garvieae is the Gram-positive cocci bacteria known as the causative agent of infectious systemic disease. It causes fatal hemorrhagic septicemia in mainly cultured fish species, animals, and humans worldwide. Comparative genome analyses provide valuable information about genome identification and unique genomic features. In this study, the available L. garvieae genomes are evaluated by comparative genomics approaches. The results indicated that there are four distinct genetic groups of L. garvieae based on the Average Nucleotide Identity (ANI) value. The phylogenetic tree was produced using 16S rRNA sequence has similar genetic variances with the publicly available L. garvieae genome data on NCBI and supports the ANI value. In silico analysis of antimicrobial resistance revealed that each L. garvieae genome groups have unique antimicrobial resistance class genes, even though, all genomes have a common antibiotic-resistant class. Analyzing results of the antimicrobial resistance supports the L. garvieae genetic variations. This extensively comparative approach will provide new insights into the understanding of L. garvieae genomic diversity and antimicrobial resistance.

Keywords

Antibiotic resistance , Comparative genomics , Phylogenetic tree, , Lactococcus garvieae

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

Araştırma Makalesi

Yazarlar

Salih Kumru ^*
0000-0002-2309-3110
Türkiye

Yayımlanma Tarihi

31 Aralık 2021

Gönderilme Tarihi

28 Temmuz 2021

Kabul Tarihi

4 Kasım 2021

Yayımlandığı Sayı

Yıl 2021 Cilt: 6 Sayı: 4

DOI

https://doi.org/10.35229/jaes.894280

IZ

https://izlik.org/JA67BW72MM

APA

Kumru, S. (2021). Diversity of Lactococcus garvieae by Genomic Approaches. Journal of Anatolian Environmental and Animal Sciences, 6(4), 506-513. https://doi.org/10.35229/jaes.894280

Cited By

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Journal of Anatolian Environmental and Animal Sciences

https://doi.org/10.35229/jaes.1513751

JAES, 2016- 11.yıl

Arşiv

Cilt: 6 Sayı: 4 , 31.12.2021

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