Maksiller Sinüste Tekrarlayan Mukoepidermoid Karsinom

Year 2024, , 80 - 83, 16.08.2024

Selin Alacahan , Büşra Geçgil , Arife Beyza Doğan , Fatma Şenel , Hatice Karaman

https://doi.org/10.55694/jamer.1407499

Abstract

Mukoepidermoid karsinom, tükürük bezlerinde ortaya çıkan bir kanser türüdür ve en sık parotis bezinde bulunmasına rağmen
maksiller sinüste de görülebilir. Bu kanser için çok nadir bir yerleşim yeridir, ancak önemli zorluklara yol açabilir. Hastamız
burun tıkanıklığı ve burun kanaması gibi nonspesifik semptomlarla hastaneye kaldırıldı. Biyopsinin histopatolojik ve immüno-
histokimyasal incelemesi sonrasında tanı “mukoepidermoid karsinom” olarak konuldu. Kitle anatomik konumundan dolayı tam
olarak çıkarılamadığı için ameliyat sonrası radyoterapi uygulandı. Tümör iki yıllık bir süreden sonra hastada tekrarladı. Bu
yazıda maksiller sinüste tekrarlayan mukoepidermoid karsinom vakasını sunuyoruz.

Keywords

Maksiller sinüs, mukoepidermoid karsinom, tekrarlayan

Recurrent Mucoepidermoid Carcinoma of the Maxillary Sinus

Abstract

Mucoepidermoid carcinoma is a type of cancer that originates in the salivary glands, and while it’s most commonly found in the
parotid gland, it can also occur in the maxillary sinus. This is a very rare location for the cancer, but it can present significant
challenges. Our patient was admitted to the hospital presenting with nonspecific symptoms such as nasal obstruction and nasal
bleeding. Following a histopathological and immunohistochemical examination of the biopsy, the diagnosis of was diagnosed
as “mucoepidermoid carcinoma.” Postoperative radiotherapy was administered due to the incomplete removal of the mass
caused by its anatomical location. The tumor recurred in the patient after a two-year period. In this article, we present a case
of recurrent mucoepidermoid carcinoma in the maxillary sinus.

Keywords

Maksillary sinus, mucoepidermoid carcinoma, recurrent

Ethical Statement

-

Supporting Institution

-

References

• 1. Dulguerov P, Jacobsen MS, Allal AS, Lehmann W, Calcaterra T. Nasal and paranasal sinus carcinoma: are we making progress? A series of 220 patients and a systematic review. Cancer. 2001 Dec 15;92(12):3012-3029.
• 2. Osguthorpe JD, Richardson M. Frontal sinus malignancies. Otolaryngol Clin North Am 2001;34:269-281.
• 3. Bhattacharyya N. Survival and staging characteristics for nonsquamous cell malignancies of the maxillary sinus. Arch Otolaryngol Head Neck Surg 2003;129:334-337.
• 4. ‘t Mannetje A, Kogevinas M, Luce D, Demers PA, Bégin D, BolmAudorff U, et al. Sinonasal cancer, occupation, and tobacco smoking in European women and men. Am J Ind Med. 1999 Jul;36(1):101- 107.
• 5. Carrau RL, Myers EN, Johnson JT. Paranasal sinus carcinoma - diagnosis, treatment, and prognosis. Oncology 1992;6:43-50.
• 6. Bishop JA. Recently described neoplasms of the sinonasal tract. Semin Diagn Pathol. 2016 Mar;33(2):62-70.
• 7. Seifert G, Sobin LH. Histological typing of salivary gland tumours. In International Classification of tumours. New York: SpringerVerlag; 1991.
• 8. Brookstone MS, Huvos AG. Central salivary gland tumors of the maxilla and mandible: A clinicopathologic study of 11 cases with an analysis of the literature. J Oral Maxillofac Surg 1992;50:229-236.
• 9. Dulguerov P, Jacobsen MS, Allal AS, Lehmann W, Calcaterra T. Nasal and paranasal sinus carcinoma: are we making progress? A series of 220 patients and a systematic review. Cancer. 2001 Dec 15;92(12):3012-3029.
• 10. Stevens CM, Huang SH, Fung S, Bayley AJ, Cho JB, Cummings BJ, et al. Retrospective study of palliative radiotherapy in newly diagnosed head and neck carcinoma. Int J Radiat Oncol Biol Phys. 2011 Nov 15;81(4):958-963.
• 11. Triantafillou V, Maina IW, Kuan EC, Kohanski MA, Tong CC, Patel NN, et al. Sinonasal mucoepidermoid carcinoma: a review of the National Cancer Database. Int Forum Allergy Rhinol. 2019 Sep;9(9):1046-1053.
• 12. Barcello AN, Carvalbo CP, Teixeria DC, Machado JA, Barreiro AC, Barcellos TN. A rare case of mucoepidermoid carcinoma of the nasal septum. Intl Arch Otorhinolarynglol. Sao Paulo 2008;12(4):582- 586.
• 13. da Cruz Perez DE, Pires FR, Lopes MA, de Almeida OP, Kowalski LP. Adenoid cystic carcinoma and mucoepidermoid carcinoma of the maxillary sinus: report of a 44-year experience of 25 cases from a single institution. J Oral Maxillofac Surg. 2006 Nov;64(11):1592- 1597.