The effects UV light exposure on hair zinc concentration in vitro
Abstract
Objectives
Low hair zinc level has been shown to be a good indicator of mild to moderate zinc deficiency. Ultraviolet (UV) radiation has mutating effects on cell DNA and induces inflammatory factors in cells. The aim of this study was to observe the in vitro effect of UV exposure, on zinc concentration of hair samples.
Material and Method
Hair samples of 72 patients were included into the study of whom the clinician suspected of zinc deficiency. Hair samples were divided into three group and treated with a phototherapy device (Davlin USA model 3 series PC/SP 311/48) and exposed to either 16,5 j/L UVA, or 4910 mj UVB or both UVA and UVB together, for 8 times within 24 hour intervals. Zinc measurements of hair sample pairs (UV exposed or not) were analyzed concurrently by atomic absorption spectrophotometry (AAS).
Results
Hair samples of 72 patients (female 45, male 27) were included into the study. Mean age of patients was 6.1±3.6 years (min-max 1.0-15 years). Zinc concentration of hair was 120.9±82.0 µg/gr before UV exposure and 109.2±71.0 µg/gr after UV exposure (p=0.002). Decrease in hair zinc was not associated with gender and was significant in group both UVA and UVB exposed (p=0.01).
Conclusion
Hair zinc level was significantly reduced in UV exposed samples in concurrently analyzed before and after UV exposed hair samples. The most decrease was with UVA+UVB exposure which is also present in the sunlight. Further investigations with in vivo studies also lightening the mechanism of zinc decrease in hair are needed.
Keywords
References
- Maywald M, Rink L. Zinc homeostasis and immunosenescence. J Trace Elem Med Biol. 2015; 29:24-30.
Details
Primary Language
English
Subjects
-
Journal Section
Research Article
Authors
Çiğdem Karakükcü
KAYSERİ EĞİTİM VE ARAŞTIRMA HASTANESİ
Türkiye
Ragıp Ertaş
This is me
Kemal Özyurt
This is me
Yılmaz Ulaş
This is me
Sinem Yıldız
This is me
Publication Date
August 23, 2017
Submission Date
August 16, 2017
Acceptance Date
August 23, 2017
Published in Issue
Year 2017 Volume: 2 Number: 2