The Contribution of Perfusion MR and MR Spectroscopy Sequences to Conventional Sequences in the Staging Of Glial Tumors

Abstract

Aim: To demonstrate their contribution to staging by adding MRP and MRS to conventional MRI sequences in cerebral glial tumor cases. Material and Method: Twenty-six patients (F/M:12/14, mean age 45.6±17.3) with primary glial tumors on MRI were included in the study prospectively. The lesions included in the study were single lesions, supratentorial and inter-axial localization. All lesions were diagnosed histopathologically. Conventional MRI, MRP and MRS images were taken sequentially in a single session to all patients. The parameters obtained from these images were analyzed statistically. Results: For low/high stage tumor differentiation, the sensitivity of conventional MRI staging was 100% with a specificity of 57%. Separately assessing the sensitivity and specificity rates for conventional MRI, MRP and MRS, the combined use of conventional MRI+MRP (rCBV), conventional MRI+MRS (LL peak) and conventional MRI+MRP (rCBV)+MRS (LL peak) were observed to increase the specificity rates of conventional MRI. rCBV value and LL peak were found to be significant for the differentiation of low-stage/high-stage brain tumors. Conclusion: The conventional MRI has high sensitivity and low specificity for preoperative glioma staging. The specificity of conventional MRI findings increases when MRP and MRS are added to it.

Keywords

• glial tumors
• Perfusion Magnetic Resonance Imaging
• Magnetic Resonance Spectroscopy

Perfüzyon MR ve MR Spektroskopi Sekanslarının Glial Tümörlerin Evrelendirilmesinde Konvansiyonel Sekanslara Katkısı

Abstract

Amaç: Serebral glial tümör olgularında konvansiyonel MRI sekanslarına MRP ve MRS eklenerek evrelemeye katkılarını göstermek. Gereç ve Yöntem: MRG'de primer gliyal tümörlü 26 hasta (K / A: 12/14, ort. Yaş 45.6 ± 17.3) prospektif olarak çalışmaya alındı. Çalışmaya dahil edilen lezyonlar tek lezyonlar, supratentoryal ve intra-aksiyel lokalizasyon idi. Tüm lezyonlara histopatolojik olarak tanı konuldu. Tüm hastalara tek bir seansta konvansiyonel MRI, MRP ve MRS görüntüleri alındı. Bu görüntülerden elde edilen parametreler istatistiksel olarak analiz edildi. Bulgular: Düşük / yüksek evre tümör evrelemesi için konvansiyonel MRG evrelemesinin duyarlılığı % 100 özgüllük ile % 100 idi. Konvansiyonel MRI, MRP ve MRS için duyarlılık ve özgüllük oranlarının ayrı ayrı değerlendirilmesi, konvansiyonel MRI + MRP (rCBV), konvansiyonel MRI + MRS (LL pik) ve konvansiyonel MRI + MRP (rCBV) + MRS (LL pik) geleneksel MRG'nin özgüllük oranlarını arttırdığı gözlendi. rCBV değeri ve LL pikinin düşük evre / yüksek evre beyin tümörlerinin farklılaşması için anlamlı olduğu bulunmuştur. Sonuç: Konvansiyonel MRG'nin preoperatif glioma evrelemesi için yüksek duyarlılığı ve düşük özgüllüğü vardır. MRP ve MRS eklendiğinde konvansiyonel MRG bulgularının özgüllüğü artar.

Keywords

• glial tümörler
• Perfüzyon MRG
• MR Spektroskopi

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