Sitomegalovirus Enfeksiyonuna Bağlı Ciddi Trombositopeni

Year 2016, Volume: 1 Issue: 1, 1 - 7, 15.08.2016

Yasemin Altuner Torun Ayşe Betül Ergül Meriban Karadoğan Fatma Türkan Mutlu

Abstract

Sitomegalovirüs (CMV) enfeksiyonu immün sistemi
normal olanlar bireylerde genellikle asemptomatik seyretmekle birlikte nadiren ciddi
klinik tablolar tanımlanmıştır. Sağlıklı erişkinlerde CMV enfeksiyonu sonrası
ciddi trombositopeni gelişen vakalar bildirilmiş olmasına rağmen çocuklarda
bildirilen vaka sayısı azdır.  CMV
enfeksiyonuna bağlı trombositopenide tedavide ilk seçenek steroidlerdir,
bununla birlikte dirençli vakalarda intravenöz immunglobulin (İVİG) tedavisi
oldukça etkili olmaktadır. Biz bu yazıda CMV enfeksiyonu sonrasında   trombositopeni
gelişen ve  İVİG tedavisine dramatik
yanıt alınan  bir çocuk hastayı sunduk.

Abstract

Cytomegalovirus (CMV) infection is generally
asymptomatic in the immunocompetent  hosts
and rarely defined as a severe clinical situation . However there have been
several case reports of trombocytopenia after CMV infections in adults,  there are few reports about pediatric cases. The
first choice in trombocytopenia related with CMV infections is streroids,  in refractory cases  intravenous
immunoglobulin (IVIG) therapy is very effective. In this article  we describe a pediatric patient  who has trombocytopenia after CMV infection
and be dramatically treated by IVIG therapy.

Keywords

sitomegalovirüs, trombositopeni, intravenöz immunglobulin

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