Research Article
BibTex RIS Cite

The Effects of Ventilation During Cardiopulmonary Resuscitation Using Manual Bag-Valve or Mechanical Ventilator on the Return of Spontaneous Circulation and Lactate Levels

Year 2024, Volume: 9 Issue: 3, 107 - 113, 31.12.2024
https://doi.org/10.55694/jamer.1554074

Abstract

Aim: The aim is to investigate the effect of manual ventilation using a bag-valve versus mechanical ventilation on the return of
spontaneous circulation and the progression of lactate levels during cardiopulmonary resuscitation.
Materials and Methods: The study was conducted at the Emergency Medicine Department of Fatih Sultan Mehmet Training and
Research Hospital, between January 4, 2019, and January 4, 2021, following ethical approval. It was designed as a prospective,
randomized study. Advanced cardiac life support was administered to patients who presented with cardiac arrest. The patients
were randomized into two groups, with 15 patients included in each group. The resuscitation team provided manual ventilation
with a bag-valve for one group and mechanical ventilation in ‘CPR mode’ for the other group. Lactate levels at 0, 5, 10, 15, and
20 minutes during the intervention, as well as the duration of return of spontaneous circulation, if achieved, were recorded and
compared between the groups.
Results: The mean age of the patients was 47.8, with 16 male and 14 female patients. CPR was applied for a minimum of
20 minutes. Return of spontaneous circulation (ROSC) was achieved in 4 patients. Lactate levels showed a decrease in the
mechanical ventilator group, while an increasing trend was observed in the bag-valve manual ventilation group. There was no
significant difference between the groups regarding the effect of the ventilation method on the return of spontaneous circulation
(p > 0.05).
Conclusion: It was observed that the use of a mechanical ventilator instead of manual bag-valve ventilation did not negatively
affect the return of spontaneous circulation. Furthermore, a tendency for lactate levels to decrease was noted in the mechanical
ventilation group compared to the bag-valve manual ventilation group.

References

  • 1. Panchal AR, Bartos JA, Cabañas JG, Donnino MW, Drennan IR, Hirsch KG, et al. Part 3: Adult basic and advanced life support: 2020 American heart association guidelines for cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2020;142(16_Suppl_2):366-468.
  • 2. Aufderheide TP, Lurie KG. Death by hyperventilation: a common and life-threatening problem during cardiopulmonary resuscitation. Critical Care Medicine. 2004;32(9):345-351.
  • 3. Gaither JB, Spaite DW, Bobrow BJ, Denninghoff KR, Stolz U, Beskind DL, et al. Balancing the potential risks and benefits of outof-hospital intubation in traumatic brain injury: the intubation/ hyperventilation effect. Annals of Emergency Medicine. 2012;60(6):732-736.
  • 4. Carlson JN, Wang HE. Optimal airway management in cardiac arrest. Critical Care Clinics. 2020;36(4):705-714.
  • 5. Di Mauro FM, Schoeffler GL. Point of care measurement of lactate. Topics in Companion Animal Medicine. 2016;31(1):35-43.
  • 6. Hernandez G, Boerma EC, Dubin A, Bruhn A, Koopmans M, Edul VK, et al. Severe abnormalities in microvascular perfused vessel density are associated to organ dysfunctions and mortality and can be predicted by hyperlactatemia and norepinephrine requirements in septic shock patients. Journal of Critical Care. 2013;28(4):538. e9-. e14.
  • 7. Levitt DG, Levitt JE, Levitt MD. Quantitative assessment of blood lactate in shock: Measure of hypoxia or beneficial energy source. Biomed Res Int. 2020 Oct 14;2020:2608318.
  • 8. Cordioli RL, Brochard L, Suppan L, Lyazidi A, Templier F, Khoury A, et al. How ventilation is delivered during cardiopulmonary resuscitation: an international survey. Respiratory Care. 2018;63(10):1293-1301.
  • 9. O’Neill JF, Deakin CD. Do we hyperventilate cardiac arrest patients?. Resuscitation. 2007;73(1):82-85.
  • 10. Nikolla DA, Kramer BJ, Carlson JN. A cross-over trial comparing conventional to compression-adjusted ventilations with metronome-guided compressions. Prehospital and Disaster Medicine. 2019;34(2):220-223.
  • 11. Aufderheide TP, Sigurdsson G, Pirrallo RG, Yannopoulos D, McKnite S, Von Briesen C, et al. Hyperventilation-induced hypotension during cardiopulmonary resuscitation. Circulation. 2004;109(16):1960-1965.
  • 12. Allen SG, Brewer L, Gillis ES, Pace NL, Sakata DJ, Orr JA. A turbine-driven ventilator improves adherence to advanced cardiac life support guidelines during a cardiopulmonary resuscitation simulation. Respiratory Care. 2017;62(9):1166-1170.
  • 13. Kill C, Galbas M, Neuhaus C, Hahn O, Wallot P, Kesper K, et al. Chest compression synchronized ventilation versus intermitted positive pressure ventilation during cardiopulmonary resuscitation in a pig model. Plos One. 2015;10(5):e0127759.
  • 14. Speer T, Dersch W, Kleine B, Neuhaus C, Kill C. Mechanical ventilation during resuscitation: how manual chest compressions affect a ventilator’s function. Advances in Therapy. 2017;34(10):2333-2344.
  • 15. Tan D, Xu J, Shao S, Fu Y, Sun F, Zhang Y, et al. Comparison of different inspiratory triggering settings in automated ventilators during cardiopulmonary resuscitation in a porcine model. Plos One. 2017;12(2):e0171869.
  • 16. Luo J, Wang X, Cai T, Jiang W. Study of setting of ventilator volume tidal and airway pressure alarm threshold with continuous extrasternum heart compression in cardiopulmonary resuscitation. Chinese Critical Care Medicine. 2013;25(2):102-105.

Kardiyopulmoner Resüsitasyon Sırasında Ventilasyonun Manuel Balon-Valf Veya Mekanik Ventilatör İle Sağlanmasının Spontan Dolaşımın Geri Dönüşü Ve Laktat Düzeyi Üzerine Etkisi

Year 2024, Volume: 9 Issue: 3, 107 - 113, 31.12.2024
https://doi.org/10.55694/jamer.1554074

Abstract

Amaç: Kardiyopulmoner resüsitasyon sırasında balon-valf ile manuel olarak uygulanan ventilasyon ile mekanik ventilatör
aracılığıyla uygulanan ventilasyonun spontan dolaşımın geri dönüşü ve laktat düzeyinin seyri üzerine etkisini araştırmaktır.
Gereç ve Yöntemler: Çalışma; Sağlık Bilimleri Üniversitesi İstanbul Fatih Sultan Mehmet Eğitim ve Araştırma Hastanesi
Acil Tıp Kliniği’nde 04.01.2019 ile 04.01.2021 tarihleri arasında etik kurul onayı alınmasını takiben yürütüldü. Prospektif,
randomize olarak tasarlanan çalışma kliniğimize gelen kardiyak arrest hastalar üzerinde yapıldı. Kardiyak arrest olarak gelen
hastalara Güncel American Heart Association İleri Kardiyak Yaşam Desteği algoritmasına uygun bir şekilde ileri kardiyak
yaşam desteği başlandı ve yönetildi, hastaların ileri havayolu endotrakeal entübasyon ile sağlandı. Hastalar randomize edilerek
iki gruba ayrıldı. Her gruba 15’er hasta dahil edildi. Resüsitasyon ekibi tarafından bir gruba balon-valf ile manuel; diğer gruba
da mekanik ventilatör ile ‘KPR modu’nda ventilasyon yapıldı. Müdahale boyunca 0-5-10-15-20. dakikalardaki laktat düzeyleri,
spontan dolaşımın geri dönüşü sağlanması, sağlandı ise süresi kaydedildi ve gruplar arasında karşılaştırıldı.
Bulgular: Hastaların yaş ortalaması 47.8 ve 16sı erkek 14ü kadın cinsiyette idi. Minimum 20 dk kardio pulmoner resüsitasyon
uygulandı. 4 hastada rosc sağlandı. Laktat düzeyleri mekanik ventilatör grubunda 0-20. dakika arasında azalırken balon-valf
ile manuel ventilasyon grubunda artış eğiliminde izlendi. Ventilasyon yönteminin spontan dolaşımın geri dönüşü üzerine etkisi
açısından gruplar arasında anlamlı bir fark bulunmadı (p>0.05).
Sonuç: Mekanik ventilatör kullanımının, manuel bag-valve ventilasyon yerine spontan dolaşımın geri dönüşünü olumsuz
etkilemediği gözlemlendi. Ayrıca, mekanik ventilasyon grubunda, bag-valve manuel ventilasyon grubuna kıyasla laktat seviyelerinin düşme eğiliminde olduğu not edilmiştir.

Ethical Statement

Çalışmamı karar no:2019/21 ve tarih:14.11.2019 etik kurul onayı ile yürüttüğümü beyan ederim.

References

  • 1. Panchal AR, Bartos JA, Cabañas JG, Donnino MW, Drennan IR, Hirsch KG, et al. Part 3: Adult basic and advanced life support: 2020 American heart association guidelines for cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2020;142(16_Suppl_2):366-468.
  • 2. Aufderheide TP, Lurie KG. Death by hyperventilation: a common and life-threatening problem during cardiopulmonary resuscitation. Critical Care Medicine. 2004;32(9):345-351.
  • 3. Gaither JB, Spaite DW, Bobrow BJ, Denninghoff KR, Stolz U, Beskind DL, et al. Balancing the potential risks and benefits of outof-hospital intubation in traumatic brain injury: the intubation/ hyperventilation effect. Annals of Emergency Medicine. 2012;60(6):732-736.
  • 4. Carlson JN, Wang HE. Optimal airway management in cardiac arrest. Critical Care Clinics. 2020;36(4):705-714.
  • 5. Di Mauro FM, Schoeffler GL. Point of care measurement of lactate. Topics in Companion Animal Medicine. 2016;31(1):35-43.
  • 6. Hernandez G, Boerma EC, Dubin A, Bruhn A, Koopmans M, Edul VK, et al. Severe abnormalities in microvascular perfused vessel density are associated to organ dysfunctions and mortality and can be predicted by hyperlactatemia and norepinephrine requirements in septic shock patients. Journal of Critical Care. 2013;28(4):538. e9-. e14.
  • 7. Levitt DG, Levitt JE, Levitt MD. Quantitative assessment of blood lactate in shock: Measure of hypoxia or beneficial energy source. Biomed Res Int. 2020 Oct 14;2020:2608318.
  • 8. Cordioli RL, Brochard L, Suppan L, Lyazidi A, Templier F, Khoury A, et al. How ventilation is delivered during cardiopulmonary resuscitation: an international survey. Respiratory Care. 2018;63(10):1293-1301.
  • 9. O’Neill JF, Deakin CD. Do we hyperventilate cardiac arrest patients?. Resuscitation. 2007;73(1):82-85.
  • 10. Nikolla DA, Kramer BJ, Carlson JN. A cross-over trial comparing conventional to compression-adjusted ventilations with metronome-guided compressions. Prehospital and Disaster Medicine. 2019;34(2):220-223.
  • 11. Aufderheide TP, Sigurdsson G, Pirrallo RG, Yannopoulos D, McKnite S, Von Briesen C, et al. Hyperventilation-induced hypotension during cardiopulmonary resuscitation. Circulation. 2004;109(16):1960-1965.
  • 12. Allen SG, Brewer L, Gillis ES, Pace NL, Sakata DJ, Orr JA. A turbine-driven ventilator improves adherence to advanced cardiac life support guidelines during a cardiopulmonary resuscitation simulation. Respiratory Care. 2017;62(9):1166-1170.
  • 13. Kill C, Galbas M, Neuhaus C, Hahn O, Wallot P, Kesper K, et al. Chest compression synchronized ventilation versus intermitted positive pressure ventilation during cardiopulmonary resuscitation in a pig model. Plos One. 2015;10(5):e0127759.
  • 14. Speer T, Dersch W, Kleine B, Neuhaus C, Kill C. Mechanical ventilation during resuscitation: how manual chest compressions affect a ventilator’s function. Advances in Therapy. 2017;34(10):2333-2344.
  • 15. Tan D, Xu J, Shao S, Fu Y, Sun F, Zhang Y, et al. Comparison of different inspiratory triggering settings in automated ventilators during cardiopulmonary resuscitation in a porcine model. Plos One. 2017;12(2):e0171869.
  • 16. Luo J, Wang X, Cai T, Jiang W. Study of setting of ventilator volume tidal and airway pressure alarm threshold with continuous extrasternum heart compression in cardiopulmonary resuscitation. Chinese Critical Care Medicine. 2013;25(2):102-105.
There are 16 citations in total.

Details

Primary Language English
Subjects Emergency Medicine
Journal Section Makale
Authors

Güven Yılmaz 0000-0002-0565-6143

Burcu Azapoğlu Kaymak 0000-0001-7517-8637

Tuba Cimilli 0000-0002-4760-0076

Emre Yılmaz 0009-0006-1236-4532

Serhat Ersöz 0009-0000-3838-5725

Mustafa Çalık 0000-0002-3184-2943

Publication Date December 31, 2024
Submission Date September 22, 2024
Acceptance Date December 23, 2024
Published in Issue Year 2024 Volume: 9 Issue: 3

Cite

Vancouver Yılmaz G, Azapoğlu Kaymak B, Cimilli T, Yılmaz E, Ersöz S, Çalık M. The Effects of Ventilation During Cardiopulmonary Resuscitation Using Manual Bag-Valve or Mechanical Ventilator on the Return of Spontaneous Circulation and Lactate Levels. JAMER. 2024;9(3):107-13.