Here in we present a case of a postoperative jaundice due to Gilbert's syndrome in a patient who was suffering from coronary artery disease and undergone coronary artery bypass grafting operation. Signs and symptoms of jaundice developed on the postoperative first day and resolved spontaneously after 7 days. The diagnosis and characteristics of Gilbert's syndrome and other related abnormalities and factors relevant to anesthesia and cardiopulmonary by-pass, which affect bilirubin metabolism, are discussed.
Strassburg CP. Hyperbilirubinemia syndromes (GilbertMeulengracht, Crigler-Najjar, Dubin-Johnson, and Rotor syndrome). Best Pract Res Clin Gastroenterol 2010;24(5):555-71.
Bosma PJ. Inherited disorder of bilirubin metabolism. J Hepatol 2003;38(1):107-17.
Foulk WT, Butt HR, Owen CA Jr, Whitcomb FF Jr,Mason HL. Constitutional hepatic dysfunction (Gilbert’s syndrome): its natural history and related syndromes. Medicine (Baltimore) 1959;38(1):25-46.
Vítek L, Jirsa M, Brodanová M, Kalab M, Marecek Z, Danzig V, Novotný L, Kotal P. Gilbert syndrome and ischemic heart disease: a protective effect of elevated bilirubin levels. Atherosclerosis 2002;160(2):449-56.
Schwertner HA, Jackson WG, Tolan G. (1994) Association of low serum concentration of bilirubin with increased risk of coronary artery disease. Clin Chem 1994;40(1):18-23.
Macklon AF, Savage RL, Rawlins MD. Gilbert’s syndrome and drug metabolism. Clin Pharmacokinet 1979;4(3):223-32.
Gilbert sendromlu bir hastada coroner arter bypass greftlemesi
Year 2012,
Volume: 3 Issue: 4, 555 - 557, 01.12.2012
Biz bu çalışmamızda; koroner arter bypass greftleme operasyonu yaptığımız koroner arter hastasında, Gilbert sendromuna bağlı postoperatif sarılığı sunduk. Sarılık belirti ve bulguları post-operatif birinci günde başlayıp,post-operatif yedinci günde kendiliğinden kayboldu.Gilbert sendromunun tanısı,özellikleri ve ilişkili diğer anormallikler ile birlikte anestezi ve kardiyopulmoner bypass'ın bilirübin metabolizmasına etkileri tartışıldı.
Strassburg CP. Hyperbilirubinemia syndromes (GilbertMeulengracht, Crigler-Najjar, Dubin-Johnson, and Rotor syndrome). Best Pract Res Clin Gastroenterol 2010;24(5):555-71.
Bosma PJ. Inherited disorder of bilirubin metabolism. J Hepatol 2003;38(1):107-17.
Foulk WT, Butt HR, Owen CA Jr, Whitcomb FF Jr,Mason HL. Constitutional hepatic dysfunction (Gilbert’s syndrome): its natural history and related syndromes. Medicine (Baltimore) 1959;38(1):25-46.
Vítek L, Jirsa M, Brodanová M, Kalab M, Marecek Z, Danzig V, Novotný L, Kotal P. Gilbert syndrome and ischemic heart disease: a protective effect of elevated bilirubin levels. Atherosclerosis 2002;160(2):449-56.
Schwertner HA, Jackson WG, Tolan G. (1994) Association of low serum concentration of bilirubin with increased risk of coronary artery disease. Clin Chem 1994;40(1):18-23.
Macklon AF, Savage RL, Rawlins MD. Gilbert’s syndrome and drug metabolism. Clin Pharmacokinet 1979;4(3):223-32.
Korkmaz, K., Gedik, H. S., & Deniz, H. (2012). Gilbert sendromlu bir hastada coroner arter bypass greftlemesi. Journal of Clinical and Experimental Investigations, 3(4), 555-557. https://doi.org/10.5799/ahinjs.01.2012.04.0223
AMA
Korkmaz K, Gedik HS, Deniz H. Gilbert sendromlu bir hastada coroner arter bypass greftlemesi. J Clin Exp Invest. December 2012;3(4):555-557. doi:10.5799/ahinjs.01.2012.04.0223
Chicago
Korkmaz, Kemal, Hikmet Selcuk Gedik, and Hayati Deniz. “Gilbert Sendromlu Bir Hastada Coroner Arter Bypass Greftlemesi”. Journal of Clinical and Experimental Investigations 3, no. 4 (December 2012): 555-57. https://doi.org/10.5799/ahinjs.01.2012.04.0223.
EndNote
Korkmaz K, Gedik HS, Deniz H (December 1, 2012) Gilbert sendromlu bir hastada coroner arter bypass greftlemesi. Journal of Clinical and Experimental Investigations 3 4 555–557.
IEEE
K. Korkmaz, H. S. Gedik, and H. Deniz, “Gilbert sendromlu bir hastada coroner arter bypass greftlemesi”, J Clin Exp Invest, vol. 3, no. 4, pp. 555–557, 2012, doi: 10.5799/ahinjs.01.2012.04.0223.
ISNAD
Korkmaz, Kemal et al. “Gilbert Sendromlu Bir Hastada Coroner Arter Bypass Greftlemesi”. Journal of Clinical and Experimental Investigations 3/4 (December 2012), 555-557. https://doi.org/10.5799/ahinjs.01.2012.04.0223.
JAMA
Korkmaz K, Gedik HS, Deniz H. Gilbert sendromlu bir hastada coroner arter bypass greftlemesi. J Clin Exp Invest. 2012;3:555–557.
MLA
Korkmaz, Kemal et al. “Gilbert Sendromlu Bir Hastada Coroner Arter Bypass Greftlemesi”. Journal of Clinical and Experimental Investigations, vol. 3, no. 4, 2012, pp. 555-7, doi:10.5799/ahinjs.01.2012.04.0223.
Vancouver
Korkmaz K, Gedik HS, Deniz H. Gilbert sendromlu bir hastada coroner arter bypass greftlemesi. J Clin Exp Invest. 2012;3(4):555-7.