Öz
Here in we present a case of a postoperative jaundice due to Gilbert's syndrome in a patient who was suffering from coronary artery disease and undergone coronary artery bypass grafting operation. Signs and symptoms of jaundice developed on the postoperative first day and resolved spontaneously after 7 days. The diagnosis and characteristics of Gilbert's syndrome and other related abnormalities and factors relevant to anesthesia and cardiopulmonary by-pass, which affect bilirubin metabolism, are discussed.
Anahtar Kelimeler
Coronary artery disease coronary artery bypass grafting Gilbert\'s syndrome
Kaynakça
- Strassburg CP. Hyperbilirubinemia syndromes (GilbertMeulengracht, Crigler-Najjar, Dubin-Johnson, and Rotor syndrome). Best Pract Res Clin Gastroenterol 2010;24(5):555-71.
- Bosma PJ. Inherited disorder of bilirubin metabolism. J Hepatol 2003;38(1):107-17.
- Foulk WT, Butt HR, Owen CA Jr, Whitcomb FF Jr,Mason HL. Constitutional hepatic dysfunction (Gilbert’s syndrome): its natural history and related syndromes. Medicine (Baltimore) 1959;38(1):25-46.
- Vítek L, Jirsa M, Brodanová M, Kalab M, Marecek Z, Danzig V, Novotný L, Kotal P. Gilbert syndrome and ischemic heart disease: a protective effect of elevated bilirubin levels. Atherosclerosis 2002;160(2):449-56.
- Schwertner HA, Jackson WG, Tolan G. (1994) Association of low serum concentration of bilirubin with increased risk of coronary artery disease. Clin Chem 1994;40(1):18-23.
- Macklon AF, Savage RL, Rawlins MD. Gilbert’s syndrome and drug metabolism. Clin Pharmacokinet 1979;4(3):223-32.
Öz
Biz bu çalışmamızda; koroner arter bypass greftleme operasyonu yaptığımız koroner arter hastasında, Gilbert sendromuna bağlı postoperatif sarılığı sunduk. Sarılık belirti ve bulguları post-operatif birinci günde başlayıp,post-operatif yedinci günde kendiliğinden kayboldu.Gilbert sendromunun tanısı,özellikleri ve ilişkili diğer anormallikler ile birlikte anestezi ve kardiyopulmoner bypass'ın bilirübin metabolizmasına etkileri tartışıldı.
Anahtar Kelimeler
Koroner arter hastalığı koroner arter bypass greftleme Gilbert sendromu
Kaynakça
- Strassburg CP. Hyperbilirubinemia syndromes (GilbertMeulengracht, Crigler-Najjar, Dubin-Johnson, and Rotor syndrome). Best Pract Res Clin Gastroenterol 2010;24(5):555-71.
- Bosma PJ. Inherited disorder of bilirubin metabolism. J Hepatol 2003;38(1):107-17.
- Foulk WT, Butt HR, Owen CA Jr, Whitcomb FF Jr,Mason HL. Constitutional hepatic dysfunction (Gilbert’s syndrome): its natural history and related syndromes. Medicine (Baltimore) 1959;38(1):25-46.
- Vítek L, Jirsa M, Brodanová M, Kalab M, Marecek Z, Danzig V, Novotný L, Kotal P. Gilbert syndrome and ischemic heart disease: a protective effect of elevated bilirubin levels. Atherosclerosis 2002;160(2):449-56.
- Schwertner HA, Jackson WG, Tolan G. (1994) Association of low serum concentration of bilirubin with increased risk of coronary artery disease. Clin Chem 1994;40(1):18-23.
- Macklon AF, Savage RL, Rawlins MD. Gilbert’s syndrome and drug metabolism. Clin Pharmacokinet 1979;4(3):223-32.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Aralık 2012 |
| Yayımlandığı Sayı | Yıl 2012 Cilt: 3 Sayı: 4 |