The Early-Term Adverse Effects in Healthcare Personnel after CoronaVac Vaccination

Year 2022, , 384 - 387, 15.03.2022

Barış Çil , Mehmet Kabak

https://doi.org/10.16899/jcm.1026942

Abstract

Objectives: Among the various Covidien-19 vaccine, Sinovac vaccination program in Turkey is carried out by coronavac vaccine developed by Chinese firms. Our aim was to determine the early side effects of CoronaVac vaccine in Turkish healthcare professionals.
Materials and methods: Volunteer healthcare personnel vaccinated with CoronaVac were evaluated four weeks after the first dose. Demographic, clinical characteristics, and post-vaccination side effects were recorded. Statistical analysis was performed with SPSS 15.0 software.
Results: The study was conducted with 516 volunteers. The mean age was 34.53 ± 7.80 years, and the majority of the participants (58.1%) were women. The most common occupational nursing (34.8%) and smoking rate in the study was 27.1%. Approximately one third (31%) of the participants had a previous COVID-19 infection and antibody positivity (27.9%). The most common side effects were determined to be arm pain (55.8%) followed by headache (24.8%), fatigue (18.6%) and joint pain (7.8%). On the third day after vaccination, the diagnosis of COVID-19 was reported in one person. Four (0.8%) stated that they took a break from their daily routine due to syncope and one person due to COVID-19.
Conclusion: In this study, no life-threatening side effects were reported in the early period after CoronaVac. Among the early side effects of CoronaVac vaccine in our study, the most common side effects were Arm soreness, Headache, Fatigue and Joint pain. We argue that it is important to use multi-layered and evidence-based strategies to raise the frequency of vaccination and to address the concerns and ownership of the vaccine in relation to the COVID-19 vaccine. In order to minimize widespread information pollution and hostility associated with vaccination, healthcare professionals should lead and strongly support vaccination programs.

Keywords

CoronaVac, COVID-19, vaccination, SARS-CoV-2

CoronaVac Aşısı Sonrası Sağlık Personelinde Erken Dönem Olumsuz Etkileri

Abstract

Amaç: Çeşitli Covidien-19 aşıları arasında Türkiye'deki Sinovac aşılama programı, Çinli firmalar tarafından geliştirilen coronavac aşısı ile yürütülmektedir. Amacımız CoronaVac aşısının Türk sağlık profesyonellerinde erken yan etkilerini belirlemekti.
Metaryal metod: CoronaVac ile aşılanan gönüllü sağlık personeli, ilk dozdan dört hafta sonra değerlendirildi. Demografik, klinik özellikler ve aşılama sonrası yan etkiler kaydedildi. İstatistiksel analiz SPSS 15.0 yazılımı ile yapıldı.
Bulgular: Çalışma 516 gönüllü ile gerçekleştirilmiştir. Ortalama yaş 34.53 ± 7.80 yıl olup, katılımcıların çoğunluğu (%58.1) kadındır. Çalışmada en büyük meslek grubu hemşirelerdi(%34.8) ve sigara içme oranı %27,1 idi. Katılımcıların yaklaşık üçte biri (%31) daha önce bir COVID-19 enfeksiyonuna ve antikor pozitifliğine (%27.9) sahipti. En sık görülen yan etkilerin kol ağrısı (%55.8) olduğu, ardından baş ağrısı (%24.8), yorgunluk (%18.6) ve eklem ağrısı (%7.8) olduğu belirlendi. Aşılamadan sonraki üçüncü günde bir kişide COVID-19 teşhisi konuldu. Dördü (%0,8) senkop, bir kişi ise COVID-19 nedeniyle günlük işlerine ara verdiklerini belirtti.
Sonuç: Çalışmamızda CoronaVac aşısının erken yan etkileri arasında en sık görülen yan etkiler Kol ağrısı, Baş Ağrısı, Yorgunluk ve Eklem ağrılarıydı. Gönüllülerimizde hayatı tehdit eden herhangi bir yan etki görmedik. Aşılama sıklığını artırmak ve COVID-19 aşısıyla ilgili endişeleri gidermek için çok katmanlı ve kanıta dayalı stratejiler kullanmanın önemli olduğunu savunuyoruz. Aşılamayla ilgili yaygın bilgi kirliliğini ve düşmanlığı en aza indirmek için sağlık profesyonelleri aşı programlarına liderlik etmeli ve güçlü bir şekilde desteklemelidir.

Keywords

CoronaVac, COVID-19, aşılanma, SARS-CoV-2, yan etkiler

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