The Clinical Significance of Shock Index and GFR in the Differential Diagnosis of Perforated Appendicitis

Abstract

Aim: The aim of the study is to investigate whether the shock index (SI) and glomerular filtration rate (GFR) have significance in differentiating acute appendicitis from complicated perforated acute appendicitis. Materials-Methods: Patients were searched retrospectively on the hospital database. Age, gender, C-reactive protein (CRP), leukocyte (WBC), total bilirubin (T.BIL), urea, creatinine, pulse (NBZ), and arterial blood pressure (TA) values of the patients were searched retrospectively on the hospital database and a database was created by using these patient variables. GFR and SI were calculated by using these data. The surgical notes about patients were reviewed retrospectively, and they were divided into two groups, namely perforated appendicitis and non-perforated appendicitis. The data were analyzed to investigate whether GFR and SI were effective in predicting perforation. Results: It was observed that NB/TA value had more frequent pathological findings in patients with perforated appendicitis (p<0.001). It was found that age (p=0.001), CRP (p<0.001), WBC (p<0.001), T. BIL (p=0.002), NB (p=0.017), and NB/TA (p<0.001) values of the patients in the perforated appendicitis group were higher than those of the patients in the normal appendicitis group, while GFR (p<0.001) and TA (p<0.001) values were lower (p<0.05). Conclusion: It is thought that SI and GFR may be a prognostic parameter for showing both perforation and the associated increased mortality rate.

Keywords

• Shock Index
• Perforated Appendicitis
• Abdominal Pain

Project Number

yok

Şok İndeksi ve GFR’nin Perfore Apandisit Ayırıcı Tanısındaki Klinik Önemi

Abstract

Amaç: Çalışmanın amacı akut apandisit ile komplike olmuş perfore akut apandisit ayırımında şok indeksinin (SI) ve glomerüler filtrasyon hızı (GFR)’nin öneminin olup olmadığı araştırılmasıdır. Gereç-Yötem: Hastalar hastane veri tabanı kullanılarak retrospektif olarak taranmıştır. Hastaların yaş, cinsiyet, C-reaktif protein (CRP), lökosit (WBC), total bilirubin (T.BİL), üre, kreatinin, nabız (NBZ), arteryal tansiyon (TA) değerleri hastane kayıt sisteminden geriye dönük taranmış ve veri tabanı oluşturulmuştur. Bu veriler kullanılarak GFR ve SI hesaplanmıştır. Hastaların ameliyat notları retrospektif olarak incelenmiş ve hastalar perfore apandisit ve perfore olmayan apandisit olarak iki gruba ayrılmıştır. Veriler analiz edilerek GFR ve SI’nin perforasyonu öngörmede etkili olup olmadığı araştırılmıştır. Bulgular: Perfore apandisit hastalarında NB/TA değerinin daha sık patolojik bulguya sahip olduğu gözlenmiştir (p<0,001). Perfore apandisit grubunda yer alan hastaların Yaş (p=0,001), CRP (p<0,001), WBC (p<0,001), T. BİL (p=0,002), NB (p=0,017) ve NB/TA (p<0,001) değerlerinin normal apandisit grubunda yer alan hastalara göre daha yüksek; GFR (p<0,001) ve TA (p<0,001) değerlerinin ise normal apandisit grubunda yer alan hastalara göre daha düşük olduğu gözlenmiştir (p<0,05). Sonuç: SI’nin ve GFR’nin hem perforasyonu hem de buna bağlı artan mortalite oranını göstermede prognostik bir parametre olabileceği düşünülmektedir.

Keywords

• Şok İndeksi
• Perfore Apandisit
• Karın Ağrısı

Supporting Institution

yok

Project Number

yok

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