Akut Pankreatit Hastalarında Trombosit İndeksleri ile Uzamış Yatış Arasındaki İlişki: Retrospektif Gözlemsel Bir Çalışma

Abstract

Amaç: Akut pankreatitli hastalarda uzamış yatış ile trombosit sayısı, ortalama trombosit hacmi, trombosit kitle indeksi, platelet dağılımı ve plateletkrit değerleri arasındaki ilişkinin incelenmesi amaçlanmıştır. Gereç ve Yöntem: Bu çalışma, Haziran 2017 ile Temmuz 2021 tarihleri arasında üçüncü basamak akademik acil serviste akut pankreatit tanısı alan tüm hastaların retrospektif bir kohort çalışması olarak yürütüldü. Hastalar, hastanenin bilgisayar tabanlı veri sistemi kullanılarak kayıt altına alındı. Yedi günden uzun süren yatışlar uzamış yatış olarak kabul edildi. Bulgular: Ortanca yaşı 58 olan (25-75 persentil: 43,5-75) 752 hasta çalışmaya dahil edildi. Kaydedilen hastaların ortanca hastanede kalış süresi 4 gündü (25-75. persentil: 3-7). 166 hastanın yatış süresi uzamış yatış olarak değerlendirildi ve uzamış yatış oranı %22.1 idi. Trombosit indeksleri için univariant analizde istatistiksel olarak anlamlı bir fark olmadığını gösterildi [Platelet sayısı (p=0,543), ortalama trombosit hacmi (p=0,656), trombositkrit (p=0,427), trombosit dağılım genişliği (p=0,497) ve trombosit kitle indeksi (p=0,484)]. Sonuç: Trombosit indeksleri ile hastanede yatış süresinin uzaması arasında net bir ilişki yoktur ve akut pankreatitli hastalarda hastanede yatış süresinin uzamasını öngöremezler.

Keywords

• trombosit sayısı
• ortalama trombosit hacmi
• akut pankreatit
• uzamış yatış
• trombosit kitle indeksi

Relationship Between Platelet Indices and Prolonged Hospitalization in Patients with Acute Pancreatitis: A Retrospective Observational Study

Abstract

Aim: To investigate relationship between platelet count, platelet mass index, mean platelet volume, platelet distribution width and plateletcrit and prolonged hospitalization in patients with acute pancreatitis. Material and Method: This study was conducted as a retrospective cohort study of all patients with acute pancreatitis from a tertiary level, academic emergency department between June 2017 and July 2021. Demographics, comorbidities, laboratory parameters, length of stay in the hospital and 30-day mortality information of the patients were recorded using computer-based data system of the hospital. Hospitalizations lasting longer than 7 days were considered as prolonged hospitalization. Results: 752 patients with a median of age of 58 years (25th-75th percentiles: 43.5-75) were included in the study. The median length of hospital stay of the enrolled patients was 4 days (25th-75th percentiles: 3-7). The hospitalization of 166 patients was prolonged, and the prolonged hospitalization rate was 22.1%. The univariate analysis for platelet indices showed that there was no statistically significant difference [Platelet count (p=0.543), mean platelet volume (p=0.656), plateletcrit (p=0.427), platelet distribution width (p=0.497), and platelet mass index (p=0.484)]. Conclusion: There is no clear relationship between platelet indices and prolonged hospitalization and they could not be predictors of prolonged hospitalization in patients with acute pancreatitis.

Keywords

• platelet count
• mean platelet volume
• acute pancreatitis
• prolonged hospitalization
• platelet mass index

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