Multisystem inflammatory syndrome in a male adolescent after his second Pfizer-BioNTech COVID-19 vaccine: a report from Turkey

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread rapidly through human populations, presenting across a continuum of severity from a symptomatic carriage to multi-organ failure and death. Multisystem inflammatory syndrome in children (MIS-C) is a new phenomenon reported worldwide with temporal association with SARS-CoV-2. Multisystem inflammatory syndrome in children is a complication of the SARS-CoV-2 infection, while myocarditis is a rare adverse effect to messenger ribonucleic acid (mRNA) SARS-CoV-2 vaccines, especially in males aged 12–17 years . On the other hand, postimmunization myocarditis is a known rare adverse event after other vaccinations, such as smallpox . Today, rare cases of MIS-C and myocarditis after mRNA SARS-CoV-2 vaccinations have been reported in children or adolescents . We present details on a 15-year-old previously healthy Turkish male adolescent who fulfilled the diagnostic criteria for MIS-C after the Pfizer-BioNTech vaccine.

Keywords

• Adolescent
• covid-19
• multisystem inflammatory syndrome

Bir erkek ergende ikinci doz Pfizer-BioNTech COVID-19 aşısı sonrası multisistem inflamatuar sendrom: Türkiye'den bir rapor

Abstract

Koronavirüs 2 (SARS-CoV-2), semptomatik bir taşıyıcılıktan çoklu organ yetmezliğine ve mortaliteye neden olarak insanlar arasında hızla yayılmaya devam ediyor. Çocuklarda multisistem inflamatuar sendrom (MIS-C), SARS-CoV-2 ile giderek artan oranda dünya çapında bildirilen yeni bir fenomendir. Çocuklarda multisistem inflamatuar sendrom, SARS-CoV-2 enfeksiyonunun bir komplikasyonu iken miyokardit, haberci ribonükleik asit (mRNA) SARS-CoV-2 aşılarının, özellikle 12-17 yaş arası erkeklerde nadir görülen bir yan etkisidir. Diğer taraftan, bağışıklama sonrası miyokardit, çiçek hastalığı gibi diğer aşılardan sonra bilinen nadir bir advers olaydır. Günümüzde çocuklarda veya adolesanlarda mRNA SARS-CoV-2 aşıları sonrası nadir olarak MIS-C ve miyokardit vakaları bildirilmiştir. Pfizer-BioNTech aşısı sonrası MIS-C tanı kriterlerini karşılayan, daha önce sağlıklı olan 15 yaşında bir Türk erkek Adolesanın klinik bulgularını sunuyoruz.

Keywords

• Adolesan
• covid-19
• multisistem inflamatuar sendrom

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