The role of the De Ritis ratio in acute cholecystitis: a retrospective observational study

Year 2023, , 388 - 395, 31.05.2023

Ercan Gürlevik , Hatice Şeyma Akça , Muhammed Tahir Akça , Hilal Akça

https://doi.org/10.16899/jcm.1210142

Abstract

Aim
Our study aimed to evaluate the relationship between the De-Ritis ratio and prognosis and mortality in patients diagnosed with cholecystitis.
Materials and Methods
This retrospective observational study was conducted on patients diagnosed with acute cholecystitis who presented to the emergency medical clinic of XXX Hospital between June 1, 2020, and January 1, 2022. The Statistical Package for Social Sciences (SPSS) software (v.20; Chicago, IL, USA) was used for all statistical analyses. All results with p < 0.05 were considered statistically significant.
Results
In our study, 174 patients were included, and 50.6% of our patients were women. The mean age was 59.0 (43.2 to 71.8). A total of 2.29% of our patients died. No statistically significant relationship was found between AST, ALT, CRP, albumin, and the De-Ritis ratio and mortality (p=0.584, p=0.533, p=0.517, p=0.07, p=0.399, respectively). When mortality rates in operated patients were examined, no statistically significant correlation was found between AST, ALT, CRP, albumin, and De-Ritis rates and mortality (p=0.248, p=0.315, p=0.451, p=0.183, p=0.688, respectively)
Conclusion
To the best of our knowledge, no study has examined the relationship between cholecystitis and the De-Ritis ratio. De-Ritis ratio is not used as a prognostic marker in patients with cholecystitis.

Keywords

cholecystitis, AST, ALT, De-Ritis ratio

De Ritis oranının akut kolesistitteki rolü: retrospektif gözlemsel çalışma

Abstract

Amaç
Çalışmamızda kolesistit tanılı hastalarda De-Ritis oranı ile prognoz ve mortalite arasındaki ilişkiyi değerlendirmeyi amaçladık.
Gereç ve Yöntem
Bu retrospektif gözlemsel çalışma, 1 Haziran 2020 ile 1 Ocak 2022 tarihleri arasında XXX Hastanesi acil servisine başvuran akut kolesistit tanısı alan hastalar üzerinde yapılmıştır. Statistical Package for Social Sciences (SPSS) yazılımı (v.20; Chicago, IL, ABD) tüm istatistiksel analizler için kullanıldı. p < 0.05 olan tüm sonuçlar istatistiksel olarak anlamlı kabul edildi.
Bulgular
Çalışmamıza 174 hasta dahil edildi ve hastalarımızın %50,6'sı kadındı. Ortalama yaş 59.0 (43.2 ila 71.8) idi. Hastalarımızın toplam %2,29'u ex oldu. AST, ALT, CRP, albumin ve De-Ritis oranı ile mortalite arasında istatistiksel olarak anlamlı bir ilişki bulunmadı (sırası ile p=0,584, p=0,533, p=0,517, p=0,07, p=0,399). Ameliyatlı hastalarda mortalite oranları incelendiğinde AST, ALT, CRP, albumin ve De-Ritis oranları ile mortalite arasında istatistiksel olarak anlamlı bir ilişki bulunmadı (sırası ile p=0,248, p=0,315, p=0,451, p=0,183, p= 0.688)
Sonuç
Bildiğimiz kadarıyla, literatürde kolesistit ile De-Ritis oranı arasındaki ilişki incelenmemiştir. De-Ritis oranı kolesistitli hastalarda prognostik bir belirteç olarak kullanılmaz.

Keywords

Kolesistit, AST, ALT, De-Ritis oranı

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