Is upper gastrointestinal system screening necessary in kidney transplant candidates?

Abstract

BACKGROUND The aim of this study is to present and discuss upper gastrointestinal tract endoscopy findings in renal transplant candidates with a high incidence of gastrointestinal system diseases. METHODS Between January 2014 and December 2019, patients over the age of 18 who were on dialysis for chronic renal failure and renal transplant candidates at xxx University xxx Hospital were included in the study. Upper gastrointestinal endoscopic findings and pathology results (atrophy, helicobacter pylori and intestinal metaplasia) of the patients were retrospectively evaluated by scanning from the electronic archive system of the hospital. RESULTS The study included 105 patients. 53 (50.5%) of the patients were male. The mean age of the patients was 44.09 ± 14.16 years and there was no statistically significant difference between male and female sexes (p=0.961). The most common endoscopic findings were pangastritis (44.8%), antral gastritis (27.6%) and esophagitis (16.2%). Only 4 (3.8%) patients had duodenal ulcer. Atrophy was positive in 3 (13%) of 23 patients, HP was positive in 19 (27.1%) of 67 patients and IM was positive in 17 (24.3%) of 56 patients. CONCLUSIONS Patients who are renal transplant candidates should be reviewed for indication of routine upper endoscopic examination before transplantation to prevent upper GI tract complications that may develop after transplantation.

Keywords

• endoscopy
• renal transplant candidate
• chronic kidney disease

Böbrek nakil adaylarında üst gastrointestinal sistem taraması gerekli mi?

Abstract

AMAÇ Çalışmadaki amacımız gastrointestinal sistem hastalık insidansı yüksek olan renal nakil adayı olan hastalarda üst GIS endoskopi bulgularını sunmak ve tartışmaktır. MATERYAL METOD Ocak 2014-Aralık 2019 tarihleri arasında Karadeniz Teknik Üniversitesi Farabi Hastanesi’nde kronik böbrek yetmezliği nedeniyle diyalize giren, renal nakil adayı olan 18 yaş üstündeki hastalar çalışmaya dâhil edildi. Hastaların üst gastrointestinal endoskopik bulguları ve patoloji sonuçları (atrofi, helikobakter pylori ve intestinal metaplazi) retrospektif olarak hastanenin elektronik arşiv sisteminden taranarak değerlendirildi. BULGULAR Çalışmaya 105 hasta dâhil edildi. Hastaların 53’ü (%50,5) erkek idi. Hastaların ortalama yaşı 44,09 ± 14,16 idi, kadın ve erkek cinsiyet arasında yaş açısından istatistiksel olarak anlamlı farklılık saptanmadı (p=0,961). En sık görülen bulgular endoskopik bulgular pangastrit (%44,8), antral gastrit (%27,6) ve özofajit (%16,2) idi. Sadece 4 (%3.8) olguda duodenal ülser belirlendi. Atrofi değerlendirilmesi yapılabilen 23 hastanın 3’ünde (%13) atrofi, HP değerlendirmesi yapılan 67 hastanın 19’unda (%27,1) HP ve intestinal metaplazi (IM) değerlendirmesi yapılan 56 hastanın 17’sinde (%24,3) IM pozitif saptandı. SONUÇ Renal nakil adayı olan hastalar nakil sonrası gelişebilecek üst GI sistem komplikasyonlarının önlenmesi amacıyla nakil öncesi rutin üst endoskopik inceleme endikasyonu gözden geçirilmelidir.

Keywords

• endoskopi
• böbrek nakil adayı
• kronik böbrek hastalığı

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