The role of clinical, radiologic and laboratory markers in distinguishing an appendiceal mucocele from acute appendicitis

Year 2024, , 25 - 30, 31.01.2024

Hacı Bolat , Alirıza Erdoğan , Caner Özbey

https://doi.org/10.16899/jcm.1406168

Abstract

ABSTRACT
AIM: This study aims to assist the surgical treatment plan by increasing the rate of correct preoperative diagnoses through comparing the clinical, radiological, and laboratory findings of appendiceal mucocele (AM) and acute appendicitis (AA) before surgery.
MATERIALS AND METHODS: The study included 63 patients with a histopathologic diagnosis of AM and AA among 4867 patients who underwent appendectomy with the diagnosis of acute appendicitis in the general surgery clinic between 2009 and 2020. The patients were separated into two groups: those with AM (21 patients) and those with AA (42 patients). Age, gender, physical examination (PE), Alvarado appendicitis score, ultrasonography (USG), computed tomography (CT), laboratory, preoperative diagnosis, intraoperative diagnosis, and pathological diagnosis results of both groups were compared.

RESULTS: PE, abdominal pain, nausea, vomiting, fever symptoms, and Alvarado score were found to be significant between the two groups (p<0.05). In addition, WBC, NE, LYM %, and CRP were found to be high in group 2 (p<0.05), while there was no difference in radiological diagnosis (USG/CT) between the two groups (p<0.05). However, the appendix diameter was larger in group 1 (p<0.05). Patients with AM in 80% preoperatively, and 52% intraoperatively were operated on with a provisional diagnosis of AA. The second surgery was performed in Group 1 with a rate of 9.5% (2/21).
CONCLUSION: In our study, patients with AM who underwent surgery with a diagnosis of AA were found to differ in radiological, clinical, and laboratory findings from patients with AA.
KEYWORDS: Appendiceal Mucocele, Acute Appendicitis, Differential Diagnosis

Keywords

Appendiceal Mucocele, Acute Appendicitis, Differential Diagnosis

Ethical Statement

This study was conducted in accordance with the principles of the Declaration of Helsinki. Approval was obtained with the decision of the Ethics Committee of Niğde Ömer Halisdemir University, dated 24.12.2020 and numbered 2020/78.

Apendiks mukoselini akut apandisitten ayırmada klinik, radyolojik ve laboratuvar belirteçlerin rolü

Abstract

ÖZET
AMAÇ: Bu çalışmanın amacı; cerrahi öncesi apendiks mukoseli(AM) ile akut apandisit(AA)’i klinik, radyolojik ve laboratuvar sonuçlarını karşılaştırıp ameliyat öncesi doğru tanı oranımızı artırarak cerrahi tedavi planına yardımcı olmaktır.

GEREÇ VE YÖNTEMLER: Çalışmaya 2009-2020 yılları arasında genel cerrahi kliniğinde akut apandisit tanısıyla apendektomi yapılan 4867 hastadan histopatolojik olarak AM ve AA tanısı alan 63 hasta dahil edildi. Hastalar AM'li olanlar (21 hasta) olmak üzere iki gruba ayrıldı. ve AA'lı olanlar (42 hasta). Her iki grubun yaş, cinsiyet, fizik muayene (PE), Alvarado apandisit skoru, ultrasonografi (USG), bilgisayarlı tomografi (BT), laboratuvar, preoperatif tanı, intraoperatif tanı ve patolojik tanı sonuçları karşılaştırıldı.

BULGULAR: PE, karın ağrısı, bulantı, kusma, ateş semptomları ve Alvarado skoru iki grup arasında anlamlı bulundu (p<0,05). Ayrıca grup 2'de WBC, NE, LYM % ve CRP yüksek bulunurken (p<0,05), radyolojik tanı (USG/BT) açısından iki grup arasında fark yoktu (p<0,05). Ancak apendiks çapı grup 1'de daha büyüktü (p<0,05). AM'li hastaların %80'i ameliyat öncesi, %52'si ameliyat sırasında geçici AA tanısıyla ameliyat edildi. İkinci ameliyat ise %9,5 (2/21) oranında Grup 1'de yapıldı.

SONUÇ: Çalışmamızda AA tanısıyla ameliyat edilen AM'li hastaların radyolojik, klinik ve laboratuvar bulgularının AA'lı hastalardan farklı olduğu görüldü.

ANAHTAR KELİMELER: Apendiks Mukosel, Akut Apandisit, Ayırıcı Tanı

Keywords

Apendiks Mukosel, Akut Apandisit, Ayırıcı Tanı

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