Clinical Research

Comparative Analysis of ERCP Results in Two Elderly Cohorts: Late Elderly and Super-Aged Patients

Volume: 15 Number: 1 January 31, 2025
TR EN

Comparative Analysis of ERCP Results in Two Elderly Cohorts: Late Elderly and Super-Aged Patients

Abstract

Aims: Endoscopists may generally avoid performing ERCP in super-old patients. This is because these patients often have comorbid conditions and reduced physiological function. The aim of this study was to evaluate the efficacy and safety of ERCP in the super-old population over 85 years of age. Materials and Methods: This study was retrospectively designed in a single tertiary care centre. Patients over 75 years of age with naive papillae who underwent ERCP between February 2019 and June 2022 were included in the study. Among the patients in the study, patients over 85 years of age were defined as süper-old, and patients aged 75-84 years were defined as old. The procedural data, efficacy and procedure-related adverse events of ERCP were compared between the two groups. Results: A total of 260 patients were included, with 200 (76.9%) in the old group and 60 (23.1%) in the super-old group, of whom 37 were over 90 years old. According to the results of the analyses, only age and Charlson score showed a significant difference (p<0.001) between the demographic variables. There was no significant difference between the two groups in terms of procedural success, cannulation time, difficult cannulation, cannulation techniques and other procedural data. Cardiopulmonary complications were significantly more frequent in the super-old group (8.3% versus 2%, p=0.033). The length of hospital stay was also found to be higher in the super-old group compared to the old group (p=0.005). Conclusion: Our study demonstrated that ERCP is a safe and effective procedure in super-old patients, with no significant difference in ERCP related adverse events between elderly groups. However, cardiopulmonary complications warrant caution and may lead to longer, more complex hospitalizations for super-aged patients undergoing ERCP.

Keywords

Supporting Institution

The authors declared that this study has received no financial support.

Ethical Statement

Ethics committee approval was obtained for this study from the Bilkent City Hospital Local Ethics Committee (Date: 22.12.2021 Decision No: E2-21-1153).

References

  1. 1- World Health Organization; National Institute on Aging; National Institutes of Health. Global Health and Aging. NIH Publication No. 11-7737. Published 2011.
  2. 2- Andriulli, A., Loperfido, S., Napolitano, G., et al. Incidence rates of post-ERCP complications: a systematic survey of prospective studies. Official journal of the American College of Gastroenterology| ACG. 2007;102(8): 1781-1788.
  3. 3- Yıldırım AE, Öztürk ZA, Konduk BT, et al. The safety and efficacy of ERCP in octogenarians: a comparison of two geriatric age cohorts. Acta Gastroenterol Belg. 2017 ;80(2):263-270.
  4. 4- Han SJ, Lee TH, Kang BI, et al. Efficacy and Safety of Therapeutic Endoscopic Retrograde Cholangiopancreatography in the Elderly Over 80 Years. Dig Dis Sci. 2016;61(7):2094-3101. doi: 10.1007/s10620-016-4064-y.
  5. 5- Takahashi K, Tsuyuguchi T, Sugiyama H, et al. Risk factors of adverse events in endoscopic retrograde cholangiopancreatography for patients aged ≥85 years. Geriatr Gerontol Int. 2018 ;18(7):1038-1045. doi: 10.1111/ggi.13302.
  6. 6- Mazzola P, Spedale V. Commentary: Risk factors for complications in elderly patients aged 85 years and over undergoing endoscopic biliary stone removal. Front Surg. 2023; 10: 1139745. doi: 10.3389/fsurg.2023.1139745.
  7. 7- Ouchi Y, Rakugi H, Arai H, et al. Joint Committee of Japan Gerontological Society (JGLS) and Japan Geriatrics Society (JGS) on the definition and classification of the elderly. Redefining the elderly as aged 75 years and older: Proposal from the Joint Committee of Japan Gerontological Society and the Japan Geriatrics Society. Geriatr Gerontol Int. 2017 ;17(7):1045-1047. doi: 10.1111/ggi.13118.
  8. 8- Kazumori H, Fukuda K, Onishi K, Ohno Y. Urgent Endoscopic Retrograde Cholangiopancreatography Treatment Useful for Acute Cholangitis Caused by Bile Duct Stones in Patients Aged 90 Years and Older. Gerontology. 2024; 30:1-9. doi: 10.1159/000541636.

Details

Primary Language

English

Subjects

Gastroenterology and Hepatology

Journal Section

Clinical Research

Publication Date

January 31, 2025

Submission Date

December 30, 2024

Acceptance Date

January 27, 2025

Published in Issue

Year 2025 Volume: 15 Number: 1

APA
Cankurtaran, R. E., & Ersoy, O. (2025). Comparative Analysis of ERCP Results in Two Elderly Cohorts: Late Elderly and Super-Aged Patients. Journal of Contemporary Medicine, 15(1), 49-55. https://izlik.org/JA77JC57KL
AMA
1.Cankurtaran RE, Ersoy O. Comparative Analysis of ERCP Results in Two Elderly Cohorts: Late Elderly and Super-Aged Patients. J Contemp Med. 2025;15(1):49-55. https://izlik.org/JA77JC57KL
Chicago
Cankurtaran, Rasim Eren, and Osman Ersoy. 2025. “Comparative Analysis of ERCP Results in Two Elderly Cohorts: Late Elderly and Super-Aged Patients”. Journal of Contemporary Medicine 15 (1): 49-55. https://izlik.org/JA77JC57KL.
EndNote
Cankurtaran RE, Ersoy O (January 1, 2025) Comparative Analysis of ERCP Results in Two Elderly Cohorts: Late Elderly and Super-Aged Patients. Journal of Contemporary Medicine 15 1 49–55.
IEEE
[1]R. E. Cankurtaran and O. Ersoy, “Comparative Analysis of ERCP Results in Two Elderly Cohorts: Late Elderly and Super-Aged Patients”, J Contemp Med, vol. 15, no. 1, pp. 49–55, Jan. 2025, [Online]. Available: https://izlik.org/JA77JC57KL
ISNAD
Cankurtaran, Rasim Eren - Ersoy, Osman. “Comparative Analysis of ERCP Results in Two Elderly Cohorts: Late Elderly and Super-Aged Patients”. Journal of Contemporary Medicine 15/1 (January 1, 2025): 49-55. https://izlik.org/JA77JC57KL.
JAMA
1.Cankurtaran RE, Ersoy O. Comparative Analysis of ERCP Results in Two Elderly Cohorts: Late Elderly and Super-Aged Patients. J Contemp Med. 2025;15:49–55.
MLA
Cankurtaran, Rasim Eren, and Osman Ersoy. “Comparative Analysis of ERCP Results in Two Elderly Cohorts: Late Elderly and Super-Aged Patients”. Journal of Contemporary Medicine, vol. 15, no. 1, Jan. 2025, pp. 49-55, https://izlik.org/JA77JC57KL.
Vancouver
1.Rasim Eren Cankurtaran, Osman Ersoy. Comparative Analysis of ERCP Results in Two Elderly Cohorts: Late Elderly and Super-Aged Patients. J Contemp Med [Internet]. 2025 Jan. 1;15(1):49-55. Available from: https://izlik.org/JA77JC57KL