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Transdermal Ginseng Patches as a Rare Trigger of Psychosis: Implications for Herbal Product Safety
Abstract
This case report describes a 49-year-old woman who developed ginseng-induced psychosis after using transdermal ginseng patches. Presenting with visual hallucinations, disorganized thoughts, and anxious behavior, she had no prior psychiatric history. Diagnostic tests, including brain imaging and EEG, were normal. The patient’s symptoms resolved after discontinuing the patches and receiving risperidone. Ginseng, commonly used for physical and mental fatigue, rarely causes psychosis. This case highlights the potential psychiatric side effects of herbal products, particularly transdermal forms, which lack regulatory oversight. Emergency physicians should consider herbal use in patients with psychotic symptoms, emphasizing the need for caution and regulation of such products.
Keywords
References
- 1. Kim JH, Yi YS, Kim MY, et al. Role of ginsenosides, the main active components of Panax ginseng, in inflammatory responses and diseases. J Ginseng Res. 2017;41(4):435–443.
- 2. Lee NH, Yoo SR, Kim HG, et al. Safety and tolerability of Panax ginseng root extract: a long-term follow-up study. J Ginseng Res. 2012;36(4):331–335.
- 3. Lee S, Rhee DK. Effects of ginseng on stress-related depression, anxiety, and the hypothalamic-pituitary-adrenal axis. J Ginseng Res. 2017;41(4):589–594.
- 4. Tsuang MT, Faraone SV. The genetics of mood disorders. Baltimore, MD: Johns Hopkins University Press; 1990.
- 5. Izzo AA, Ernst E. Interactions between herbal medicines and prescribed drugs: a systematic review. Drugs. 2009;69(13):1777–1798.
- 6. Henderson GL, Harkey MR, Gershwin ME. Effects of ginseng components on cDNA-expressed cytochrome P450 enzyme catalytic activity. Life Sci. 1999;65(15):PL209–PL214.
- 7. Prausnitz MR, Langer R. Transdermal drug delivery. Nat Biotechnol. 2008;26(11):1261–1268.
- 8. Boullata JI, Nace AM. Safety issues with herbal medicine. Pharmacotherapy. 2000;20(3):257–269.
Details
Primary Language
English
Subjects
Emergency Medicine, Psychiatry
Journal Section
Case Report
Early Pub Date
May 24, 2025
Publication Date
May 31, 2025
Submission Date
March 16, 2025
Acceptance Date
May 21, 2025
Published in Issue
Year 2025 Volume: 15 Number: 3
APA
Jaradat, Ö., & Ersoy, S. (2025). Transdermal Ginseng Patches as a Rare Trigger of Psychosis: Implications for Herbal Product Safety. Journal of Contemporary Medicine, 15(3), 139-141. https://doi.org/10.16899/jcm.1659015
AMA
1.Jaradat Ö, Ersoy S. Transdermal Ginseng Patches as a Rare Trigger of Psychosis: Implications for Herbal Product Safety. J Contemp Med. 2025;15(3):139-141. doi:10.16899/jcm.1659015
Chicago
Jaradat, Ömer, and Süleyman Ersoy. 2025. “Transdermal Ginseng Patches As a Rare Trigger of Psychosis: Implications for Herbal Product Safety”. Journal of Contemporary Medicine 15 (3): 139-41. https://doi.org/10.16899/jcm.1659015.
EndNote
Jaradat Ö, Ersoy S (May 1, 2025) Transdermal Ginseng Patches as a Rare Trigger of Psychosis: Implications for Herbal Product Safety. Journal of Contemporary Medicine 15 3 139–141.
IEEE
[1]Ö. Jaradat and S. Ersoy, “Transdermal Ginseng Patches as a Rare Trigger of Psychosis: Implications for Herbal Product Safety”, J Contemp Med, vol. 15, no. 3, pp. 139–141, May 2025, doi: 10.16899/jcm.1659015.
ISNAD
Jaradat, Ömer - Ersoy, Süleyman. “Transdermal Ginseng Patches As a Rare Trigger of Psychosis: Implications for Herbal Product Safety”. Journal of Contemporary Medicine 15/3 (May 1, 2025): 139-141. https://doi.org/10.16899/jcm.1659015.
JAMA
1.Jaradat Ö, Ersoy S. Transdermal Ginseng Patches as a Rare Trigger of Psychosis: Implications for Herbal Product Safety. J Contemp Med. 2025;15:139–141.
MLA
Jaradat, Ömer, and Süleyman Ersoy. “Transdermal Ginseng Patches As a Rare Trigger of Psychosis: Implications for Herbal Product Safety”. Journal of Contemporary Medicine, vol. 15, no. 3, May 2025, pp. 139-41, doi:10.16899/jcm.1659015.
Vancouver
1.Ömer Jaradat, Süleyman Ersoy. Transdermal Ginseng Patches as a Rare Trigger of Psychosis: Implications for Herbal Product Safety. J Contemp Med. 2025 May 1;15(3):139-41. doi:10.16899/jcm.1659015