Abstract
Serous retinal detachment (SRD) is a rare but potentially vision-threatening ocular complication of hypertensive disorders of pregnancy, particularly severe preeclampsia and HELLP syndrome. It typically presents bilaterally and is believed to result from choroidal ischemia and endothelial dysfunction secondary to systemic vasospasm. Despite its dramatic clinical presentation, SRD is generally reversible with timely and appropriate management. We present a case series of four patients with SRD associated with HELLP syndrome to illustrate the clinical spectrum, imaging findings, management, and visual outcomes of this rare complication. All patients were managed conservatively after delivery with strict blood pressure control, resulting in complete anatomical resolution and full visual recovery in every case. These cases underscore the favorable prognosis of HELLP-related SRD when promptly recognized and appropriately managed, and highlight the importance of multidisciplinary collaboration.
References
- 1. American College of Obstetricians and Gynecologists. Preeclampsia and high blood pressure during pregnancy. Washington (DC): ACOG; 2023.
- 2. Sheth BP, Mieler WF. Ocular complications of pregnancy. Curr Opin Ophthalmol. 2001;12:455–63.
- 3. Benlghazi A, Bouhtouri Y, Belouad M, et al. Bilateral serous retinal detachment in pre-eclampsia: a rare but favorable complication. Oxf Med Case Reports. 2023;2023(10):omad109.
- 4. Raposo JTBV, Melo BCDS, Maciel NFBB, Leite SD, Rebelo ÓRC, Lima AMF. Serous retinal detachment in pre-eclampsia: case report and literature review. Rev Bras Ginecol Obstet. 2020;42(11):772–3.
- 5. Valluri S, Adelberg DA, Curtis RS, Olk RJ. Diagnostic indocyanine green angiography in preeclampsia. Am J Ophthalmol. 1996;122:672–7.
- 6. Iqra M, Ahmad K, Khan Z, et al. Ocular manifestations of preeclampsia and HELLP syndrome: a systematic review. BMC Ophthalmol. 2022;22:147.
- 7. Vigil-De Gracia P, Ortega-Paz L, Montufar-Rueda C. Serous retinal detachment in preeclampsia and HELLP syndrome. Int J Gynaecol Obstet. 2011;114(3):235–8.
- 8. Kaur S, Jain R, Saxena R, et al. Serous retinal detachment with peripapillary choroidopathy in HELLP syndrome. BMJ Case Rep. 2020;13:e236620.
- 9. Cunningham FG, Leveno KJ, Bloom SL, et al. Hypertensive disorders of pregnancy. In: Williams Obstetrics. 25th ed. New York: McGraw-Hill; 2018.
Abstract
Seröz retina dekolmanı (SRD), gebeliğin hipertansif hastalıklarının nadir ancak potansiyel olarak görmeyi tehdit eden bir oküler komplikasyonudur ve özellikle ağır preeklampsi ile HELLP sendromu ile ilişkilidir. Genellikle bilateral olarak ortaya çıkar ve sistemik vazospazma bağlı gelişen koroidal iskemi ve endotel disfonksiyonu sonucu oluştuğu düşünülmektedir. Klinik prezentasyonu sıklıkla dramatik olmasına rağmen, zamanında ve uygun şekilde yönetildiğinde SRD genellikle geri dönüşümlüdür.
Bu çalışmada, HELLP sendromu ile ilişkili SRD gelişen dört hastadan oluşan bir olgu serisi sunularak bu nadir komplikasyonun klinik spektrumu, multimodal görüntüleme bulguları, tedavi yaklaşımları ve görsel sonuçları ortaya konulmuştur. Tüm hastalar doğum sonrası dönemde konservatif olarak, sıkı kan basıncı kontrolü ile izlenmiştir. Tüm olgularda SRD’nin tam anatomik rezolüsyonu ve tam görsel iyileşme sağlanmıştır.
Bu olgular, HELLP sendromuna bağlı SRD’nin erken tanı ve uygun tedavi ile iyi prognoza sahip olduğunu göstermekte olup, erken farkındalık ve multidisipliner iş birliğinin önemini vurgulamaktadır.
References
- 1. American College of Obstetricians and Gynecologists. Preeclampsia and high blood pressure during pregnancy. Washington (DC): ACOG; 2023.
- 2. Sheth BP, Mieler WF. Ocular complications of pregnancy. Curr Opin Ophthalmol. 2001;12:455–63.
- 3. Benlghazi A, Bouhtouri Y, Belouad M, et al. Bilateral serous retinal detachment in pre-eclampsia: a rare but favorable complication. Oxf Med Case Reports. 2023;2023(10):omad109.
- 4. Raposo JTBV, Melo BCDS, Maciel NFBB, Leite SD, Rebelo ÓRC, Lima AMF. Serous retinal detachment in pre-eclampsia: case report and literature review. Rev Bras Ginecol Obstet. 2020;42(11):772–3.
- 5. Valluri S, Adelberg DA, Curtis RS, Olk RJ. Diagnostic indocyanine green angiography in preeclampsia. Am J Ophthalmol. 1996;122:672–7.
- 6. Iqra M, Ahmad K, Khan Z, et al. Ocular manifestations of preeclampsia and HELLP syndrome: a systematic review. BMC Ophthalmol. 2022;22:147.
- 7. Vigil-De Gracia P, Ortega-Paz L, Montufar-Rueda C. Serous retinal detachment in preeclampsia and HELLP syndrome. Int J Gynaecol Obstet. 2011;114(3):235–8.
- 8. Kaur S, Jain R, Saxena R, et al. Serous retinal detachment with peripapillary choroidopathy in HELLP syndrome. BMJ Case Rep. 2020;13:e236620.
- 9. Cunningham FG, Leveno KJ, Bloom SL, et al. Hypertensive disorders of pregnancy. In: Williams Obstetrics. 25th ed. New York: McGraw-Hill; 2018.
Details
| Primary Language | English |
|---|---|
| Subjects | Clinical Sciences (Other) |
| Journal Section | Case Report |
| Authors | |
| Submission Date | January 12, 2026 |
| Acceptance Date | February 18, 2026 |
| Publication Date | March 27, 2026 |
| DOI | https://doi.org/10.16899/jcm.1861618 |
| IZ | https://izlik.org/JA44SE23RS |
| Published in Issue | Year 2026 Volume: 16 Issue: 2 |