Research Article

DOES SERUM BILIRUBIN LEVEL PROVIDE INFORMATION ABOUT MORTALITY IN THE EMERGENCY CLINIC ?

Volume: 16 Number: 3 May 28, 2026
EN TR

DOES SERUM BILIRUBIN LEVEL PROVIDE INFORMATION ABOUT MORTALITY IN THE EMERGENCY CLINIC ?

Abstract

Aims: As the elderly population grows, so does the number of geriatric patients admitted to emergency departments. This highlights the need for new, accessible markers to assess mortality. This study investigates serum bilirubin as a potential marker. Methods: This retrospective study included 240 patients over 65 years old who presented to a university hospital emergency department over 3 months. Patients with trauma, liver or biliary tract diseases, or using hepatotoxic drugs were excluded. Results: Of the patients, 178 survived and 62 died within 30 days. Significant differences were observed between the two groups in direct bilirubin, age, albumin, lactate, BUN, and creatinine levels (p < 0.05). Logistic regression analysis showed BUN and lactate as independent predictors of mortality. Conclusion: Bilirubin levels, in addition to established markers like BUN and lactate, may be helpful in evaluating mortality risk in geriatric patients presenting to emergency departments.

Keywords

Supporting Institution

no

Project Number

05-56

Ethical Statement

University of Health Sciences Erzurum City Hospital Ethics Committee

Thanks

no

References

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  2. 2. Zengin A. Determination of Sarcopenia and Malnutrition Risk in Elderly People Living in a Nursing Home Using a Mini Nutritional Screening Test [Master's thesis]. Hasan Kalyoncu University; 2019.
  3. 3. Wagner KH, Wallner M, Mölzer C, et al. Looking to the horizon: the role of bilirubin in the development and prevention of age-related chronic diseases. Clin Sci. 2015;129(1):1-25.
  4. 4. Noriega GO, Tomaro ML, del Batlle AM. Bilirubin is highly effective in preventing in vivo δ-aminolevulinic acid-induced oxidative cell damage. Biochim Biophys Acta Mol Basis Dis. 2003;1638(2):173-8.
  5. 5. Brito MA, Silva R, Tiribelli C, Brites D. Assessment of bilirubin toxicity to erythrocytes. Implication in neonatal jaundice management. Eur J Clin Invest. 2000;30(3):239-47.
  6. 6. Dundar ZD, Kucukceran K, Ayranci MK. Blood urea nitrogen to albumin ratio is a predictor of in-hospital mortality in older emergency department patients. Am J Emerg Med. 2021;46:349-54.
  7. 7. Ong KL, Allison MA, Cheung BM, et al. The relationship between total bilirubin levels and total mortality in older adults: the United States National Health and Nutrition Examination Survey (NHANES) 1999-2004. PLoS One. 2014;9(4):e94479.
  8. 8. Vitek L, Hubacek JA, Pajak A, et al. Association between plasma bilirubin and mortality. Ann Hepatol. 2019;18(2):379-85.

Details

Primary Language

English

Subjects

Emergency Medicine, Nefroloji

Journal Section

Research Article

Publication Date

May 28, 2026

Submission Date

February 16, 2026

Acceptance Date

April 21, 2026

Published in Issue

Year 2026 Volume: 16 Number: 3

APA
Delice, O., Erkuş, E., & Akpınar, F. (2026). DOES SERUM BILIRUBIN LEVEL PROVIDE INFORMATION ABOUT MORTALITY IN THE EMERGENCY CLINIC ? Journal of Contemporary Medicine, 16(3), 130-134. https://doi.org/10.16899/jcm.1890402
AMA
1.Delice O, Erkuş E, Akpınar F. DOES SERUM BILIRUBIN LEVEL PROVIDE INFORMATION ABOUT MORTALITY IN THE EMERGENCY CLINIC ? J Contemp Med. 2026;16(3):130-134. doi:10.16899/jcm.1890402
Chicago
Delice, Orhan, Edip Erkuş, and Furkan Akpınar. 2026. “DOES SERUM BILIRUBIN LEVEL PROVIDE INFORMATION ABOUT MORTALITY IN THE EMERGENCY CLINIC ?”. Journal of Contemporary Medicine 16 (3): 130-34. https://doi.org/10.16899/jcm.1890402.
EndNote
Delice O, Erkuş E, Akpınar F (May 1, 2026) DOES SERUM BILIRUBIN LEVEL PROVIDE INFORMATION ABOUT MORTALITY IN THE EMERGENCY CLINIC ? Journal of Contemporary Medicine 16 3 130–134.
IEEE
[1]O. Delice, E. Erkuş, and F. Akpınar, “DOES SERUM BILIRUBIN LEVEL PROVIDE INFORMATION ABOUT MORTALITY IN THE EMERGENCY CLINIC ?”, J Contemp Med, vol. 16, no. 3, pp. 130–134, May 2026, doi: 10.16899/jcm.1890402.
ISNAD
Delice, Orhan - Erkuş, Edip - Akpınar, Furkan. “DOES SERUM BILIRUBIN LEVEL PROVIDE INFORMATION ABOUT MORTALITY IN THE EMERGENCY CLINIC ?”. Journal of Contemporary Medicine 16/3 (May 1, 2026): 130-134. https://doi.org/10.16899/jcm.1890402.
JAMA
1.Delice O, Erkuş E, Akpınar F. DOES SERUM BILIRUBIN LEVEL PROVIDE INFORMATION ABOUT MORTALITY IN THE EMERGENCY CLINIC ? J Contemp Med. 2026;16:130–134.
MLA
Delice, Orhan, et al. “DOES SERUM BILIRUBIN LEVEL PROVIDE INFORMATION ABOUT MORTALITY IN THE EMERGENCY CLINIC ?”. Journal of Contemporary Medicine, vol. 16, no. 3, May 2026, pp. 130-4, doi:10.16899/jcm.1890402.
Vancouver
1.Orhan Delice, Edip Erkuş, Furkan Akpınar. DOES SERUM BILIRUBIN LEVEL PROVIDE INFORMATION ABOUT MORTALITY IN THE EMERGENCY CLINIC ? J Contemp Med. 2026 May 1;16(3):130-4. doi:10.16899/jcm.1890402