Is higher mean platelet volume an additional predictive marker of oligohydramnios and polyhydramnios?
Abstract
Objectives:
Amniotic fluid abnormalities are the
leading cause of fetal morbidity and mortality. The aim of this study
was to investigate whether prepartum mean platelet volume (MPV) is associated
with and a predictable marker for oligohydramnios
(OHA)
and polyhydramnios (PHA).
Materials and Methods: In
this retrospective study, an examination was made of the records of patients
who were monitored and gave birth at Karabuk Training and Research Hospital
Gynecology and Obstetrics Clinic in 2014-2015. Patients with isolated OHA and
PHA were included in the study group and those with normal amnion fluid volume
(AFV) in the control group. A record was
made of age, obstetric and clinical history, smoking, alcohol consumption,
laboratory test results and ultrasonography reports in the third trimester of
the pregnancy.
Results: A
total of 284 pregnant women were included in the study. The MPV levels of the
OHA and PHA groups were significantly higher than those of the normal group
(p=0.000). There was no significant difference was observed between the OHA and
PHA groups (p=0.20). MPV>8.4 accurately differentiated AFV (AUC:68.8%, sensitivity:78.6%,
specificity:59.1%). MPV>8.0 accurately differentiated OHA (AUC:67.1%,
sensitivity:84.4%, specificity:50.0%). MPV>8.5 accurately
differentiated PHA (AUC:70.2%,
sensitivity:79.0%, specificity:61.4%).
Conclusion: The result of the current study shows that
screening MPV has a predictive value for OHA and PHA in pregnancies without
complications or fetal anomaly.
Keywords
References
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Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Research Article
Publication Date
September 30, 2019
Submission Date
April 15, 2019
Acceptance Date
August 15, 2019
Published in Issue
Year 2019 Volume: 9 Number: 3