Proksimal Özofagusta Heterotopik Gastrik Mukoza Prevalansı ve Klinik ve Endoskopik Bulgular Arasındaki İlişki

Abstract

Amaç

Heterotopik gastrik mukoza (HGMPE), genellikle proksimal özofagusta lokalize olan ektopik gastrik mukoza adasıdır. HGMPE' nin klinik önemi esas olarak asit üretimi ve neoplastik dönüşüm  kapasitesi ile ilişkilidir. Bu çalışmada HGMPE prevalansı ile klinik ve endoskopik bulgular arasındaki ilişkiyi araştırmayı amaçladık.

Yöntem

Aralık 2013 ile Şubat 2018 arasında Acıbadem Kayseri Hastanesi gastroenteroloji ünitesinde özofagogastroduodenoskopi yapılan 2091 kadın ve 2035 erkek toplam 4126 hasta retrospektif olarak tarandı. 54 kadın ve 68 erkekten oluşan toplam 122 HGMPE + hasta ile yaş ve cinsiyet açısından eşleştirilmiş 107 kadın ve 134 erkekten oluşan toplam 241 kişilik HGMPE - kontrol grubu çalışmaya dahil edildi.

Bulgular

Çalışmamızda HGMPE prevalansını % 2.96 olarak saptadık. Disfaji, hasta grubunda anlamlı olarak yüksek iken, kontrol grubunda abdominal ağrı daha fazlaydı. HGMPE + ve HGMPE – gruplar arasında reflü özofajit, duodenal ülser ve alt özofageal sfinkter eksikliği açısından istatistiksel olarak anlamlı bir fark bulunmadı.

Sonuç

Çalışmalar arasındaki çelişkilere rağmen, eğer endoskopist bu durumun farkında olursa  HGMPE'nin daha sık rastlanan bir endoskopik bulgu olabileceğini düşünüyoruz. Bu durumun klinik önemi ile ilgili tartışmalar devam etse de, artan sayıda neoplastik transformasyon HGMPE'nin önemini daha da artırmıştır.

Anahtar kelimeler: Heterotopik gastrik mukoza, Servikal inlet patch, Özofagus, Laringofaringeal reflü, Disfaji.

Keywords

• Heterotopik gastrik mukoza,Servikal inlet patch

The Prevalence of Heterotopic Gastric Mucosa of the Proximal Esophagus and the Relationship Between Clinical and Endoscopic Findings

Abstract

Purpose

In this study, we aimed to investigate the prevalence of HGMPE and the relationship between clinical and endoscopic findings.

 Patients and Methods

Between December 2013 and February 2018, a total of 4126 patients, 2091 women and 2035 men, who underwent esophagogastroduodenoscopy in the gastroenterology unit of Acıbadem Kayseri Hastanesi were retrospectively screened.

Totally, 122 patients, 54 women and 68 men found to have heterotopic gastric mucosa and a control group of age and sex matched 241 patients, 107 women and 134 men who do not have heterotopic gastric mucosa were included the study.

Results

We found the prevalence of HGMPE 2.96 % in our study. Dysphagia was significantly higher in the case group, whereas abdominal pain was higher in the control group.

Conclusion

Because of the controversies among the studies we think that HGMPE may be a frequent finding if the endoscopist be aware of this entity. Although the controversies remain regarding the clinical significance of this entity, increasing number of cases of neoplastic transformation has further increased the importance of HGMPE.

Keywords

• Heterotopic gastric mucosa,Cervical inlet patch,Esophagus,Laryngopharyngeal reflux,Dysphagia

References

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