Obstrüktif Uyku Apne Sendromunda Sol Ventrikül Kitlesi ve Diyastolik Fonksiyonlar

Abstract

Amaç; Bu çalışmanın amacı; Obstrüktif uyku apne sendromu (OUAS) olan hastalarda, 2-boyutlu ve pulse dalga doppler (PDD) ekokardiyografi teknikleri kullanılarak SV fonksiyonlarının değerlendirilmesidir. Yöntem; Çalışmaya polisomnografi ile OUAS tanısı konulan ve henüz tedavi uygulanmamış 40 hasta ve 28 sağlıklı birey kontrol grubu olarak alındı. Hastalara M-mod, 2- boyutlu ve PDD ekokardiyografi incelemeleri yapıldı. Bulgular; Gruplar arasında M-mode ölçümleri ile elde edilen SV sistolik ve diyastolik çapları, ejeksiyon fraksiyonları açısından fark saptanmadı. OUAS’ li grupta SV kitle ve kitle indeksi ve SV diyastolik duvar kalınlıkları, kontrol grubuna göre anlamlı olarak daha fazla tespit edildi. Transmitral diyastolik doluş parametrelerinin PDD ekokardiyografi ile yapılan incelemesinde; OUAS grupta erken diyastolik doluma ait E dalga hızında, E/A oranlarında anlamlı azalma izlendi. E dalga deselerasyon zamanı ve izovolümetrik gevşeme zamanının OUAS’ lı grupta anlamlı olarak daha uzun saptandı. Apne-hipopne indeksi ile SV diyastolik parametreler arasında ilişki saptanmadı. Sonuç; OUAS, altta yatan herhangi bir kalp hastalığı olmasa da SV kitlesini etkileyen ve hastalığın şiddetinden bağımsız olarak SV diyastolik fonksiyonlarını bozan bir durumdur. Bu nedenle OSAS hastaları kardiyak açıdan da mutlaka değerlendirilmelidir.

Keywords

• obstrüktif uyku apne sendromu,ekokardiyografi,sol ventrikül kitlesi

Left Ventricular Mass and Diastolic Functions in Obstructive Sleep Apnea Syndrome

Abstract

Objective; The aim of this study is to evaluate SV functions in two-dimensional and pulse wave doppler (PDD) echocardiography functions with obstructive sleep apnea syndrome (OSAS). Methods; Forty patients who were diagnosed with OSAS by polysomnography (not yet treated) and 28 healthy individuals were included as control group. The patients underwent M-mode, 2-dimensional and PDD echocardiography examinations. Results; There was no difference between the two groups in terms of SV systolic and diastolic diameters and ejection fractions obtained by M-mode measurements. SV mass and mass index and SV diastolic interventricular and posterior wall thicknesses were significantly higher in the the OSAS group than the control group. In the examination of the transmitral diastolic flow parameters by PDD echocardiography, there was a significant decrease in E wave velocity and E/A ratios in the OSAS group. E wave deceleration time and isovolumetric relaxation time were significantly prolonged in the OSAS group. No relation was found between apnea-hypopnea index and SV diastolic parameters. Conclusion; OSAS is a condition that affects the SV mass and impairs SV diastolic functions, regardless of the severity of the disease, even if there is no coexistent heart disease. Therefore, OSAS patients should be evaluated from the heart.

Keywords

• obstructive sleep apnea syndrome,echocardiography,left ventricular mass

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