Yaşın önemi: izole mitral darlıkta atriyal fibrilasyon için bağımsız risk faktörü

Abstract

Amaç: Atriyal fibrilasyon ritmi romatizmal mitral darlıklı hastalarda sık görülür. Mitral darlıkta AF nin oluşumunda pek çok faktörün etkili olduğu öne sürülmüştür. En önde gelen ölümcül ritim bozukluğu olması nedeniyle, bağımsız risk faktörlerinin bilinmesi atriyal fibrilasyonun tedavisi ve önlenmesi için çok önemlidir. Mevcut çalışmada orta ve ileri mitral darlıklı hastalar için atriyal fibrilasyon yönünden risk faktörlerini araştırılmıştır. Gereç ve Yöntem: Bu çalışma geriye dönük olarak orta ve ileri romatizmal mitral darlık tanılı 307 hastayı (217 kadın, 90 erkek) içerir. Çalışma grupları atriyal fibrilasyon varlığına göre sınıflandırılmıştır. Hastalar iki gruba ayrılmışlardır, grup 1 (atriyal fibrilasyonlu hastalar, 188 hasta), grup 2 (atriyal fibrilasyon olmayan hastalar, 119 hasta). İki grubun karşılaştırılması yaş, ortalama kapak alanı (MVA), ortalama kapak gradiyent (MVG), sistolik pulmoner arter basıncı ( SPAP), sol atriyum çapı ve ortalama kapak skora göre yapıldı. Bulgular: Sol atriyum çapı 4.60±0.61 cm ve 4.73±0.71 cm; p=0.132) idi. MVA 1.09±0.18 cm2 ve 1.20±0.85 cm2; p=0.360 idi. MVG 11.31±3.86 mmHg ve 10.78±3.32 mmHg; p=0.251 idi. SPAP 48.41± 14.83 mmHg ve 47.80±13,45 mmHg; p=0.813 idi. Ortalama kapak skor 7.60±1.77 ve 7.72± 1.66; p=0.613 idi. Yaş ise atriyal fibrilasyonlu hastalarda belirgin olarak daha yüksekti (42.45±12.37 ve 34.77±10.50; p<0.001). Sonuç: Bu çalışma atriyal fibrilasyonun oluşumunda yaşın önemli bir etken olduğunu göstermiştir.

Keywords

• Yaş,, atriyal fibrilasyon,, atriyal fibrilasyon

The importance of age: independent risk factor for atrial fibrillation in isolated rheumatic mitral stenosis

Abstract

Aim: Atrial fibrillation (AF) is frequent in patients with rheumatic mitral stenosis (MS). Numerous factors have been proposed to support the pathogenesis of AF in mitral stenosis. Because of the most leading rhythm for morbidity and mortality, the identification of independent risk factors is very important for the prevention, and treatment of AF. The present study investigated the risk factors for atrial fibrillations with moderate to severe mitral stenosis. Material and Methods: This retrospective study included 307 patients (217 female, 90 male) with isolated moderate to severe rheumatic mitral stenosis. The populations were organized according to the existence of atrial fibrillation. The patients separated into two groups; as Group 1 with atrial fibrillation (188 patients), as Group II without atrial fibrillation (119 patients). A comparison of two groups was made according to age, MVA, MVG, SPAP, left atrium diameter and mean valve score. Results: According to group1 (atrial fibrillation group) and group 2 (no atrial fibrillation), left atrium diameter was 4.60±0.61 vs. 4.73±0.71; respectively, p=0.132, MVA was 1.09±0.18 vs. 1.20±0.85; respectively, p=0.360), MVG was 11.31±3.86 vs. 10.78±3.32; respectively, p=0.251, SPAP was 48.41± 14.83 vs. 47.80±13,45; respectively, p=0.813, and mean mitral valve score was 7.60±1.77 vs. 7.72±1.66; respectively, p=0.613. All of them were similar in both groups. Age was significantly higher in patients with atrial fibrillation (42.45±12.37 vs. 34.77±10.50; p<0.001, respectively) Conclusion: This study presented that the age is an important factor for genesis of AF.

Keywords

• Age,atrial fibrillation,, mitral stenosis

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