Stabil KOAH hastalarında yaş, vücut kitle indeksi, tam kan sayımı ve biyokimyasal parametrelerin etkileri

Year 2021, , 7 - 11, 30.01.2021

Muhammed Emin , Aydın Balcı

https://doi.org/10.16899/jcm.829476

Abstract

Amaç: Kronik obstrüktif akciğer hastalığı (KOAH) dünya çapında görülür ve esas olarak yaşlıları etkiler. KOAH'ı belirli çizgilerle tanımlamak genellikle imkansızdır ve çoğunlukla kılavuzlarla belirlenmiş tam bir tedavi prosedürü yoktur. GOLD kılavuzu, hastaları semptomlara ve eski alevlenme öyküsüne göre gruplandırmak için bölümsel bir KOAH değerlendirme yaklaşımı kullanır . Farklı patobiyolojik yolları yansıtan çeşitli biyobelirteçlerin eşzamanlı tespiti, artmış ölüm riski olan hastaların tanınmasına yardımcı olabilir Çalışmalar, obezitenin solunum mekaniği, kas rahatsızlığı ve nefes kontrolü nedeniyle genel popülasyonda azalmış akciğer fonksiyonuyla ilişkili olduğunu göstermiştir.
Gereç yöntem : Çalışmamıza ortalama yaşı 62,% 74'ü erkek olan 90 KOAH'lı hasta GOLD sınıflamasına göre A, B, C ve D olmak üzere dört gruba ayrıldı. Biyokimyasal parametreler, VKİ, yaş, cinsiyet ve hastalık şiddeti arasındaki ilişkiyi GOLD alt gruplarına göre araştırmak için analizler yapıldı..
Bulgular : KOAH Grup B'deki hastaların VKİ değerleri A grubuna göre daha yüksek iken, obezite ile KOAH şiddeti arasındaki ilişkiyi gösteren çalışmalarla uyumluydu; C ve D gruplarından yüksek olması obezite paradoksunu ortaya koyan çalışmalarla uyumluydu. Crp, Prokalsitonin, Sedimantasyon, Kalsiyum, Magnezyum seviyeleri ve diğer tam kan sayımı değerleri GOLD grupları arasında anlamlı bir fark göstermedi.
Sonuç: KOAH hastalarının genellikle 40 yaşın üzerinde olduğu ve yaşın hastalığın şiddeti ile bağlantılı olduğu önceki çalışmalarla tutarlı olduğu ortaya konulmuştur

Keywords

Vücut kitle İndeksi, tam kan parametreleri, KOAH

Supporting Institution

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Project Number

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Thanks

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Effects Of Age, Body Mass Index, Complete Blood Count Parameters, and Biochemical Parameters on Stable COPD Patients

Abstract

Aim: Chronic obstructive pulmonary disease (COPD) is worldwide and mainly affects the elderly. It is often impossible to define COPD with specific lines, and it has no complete cure procedure, mostly established by guidelines. The GOLD guideline uses a sectional COPD evaluation approach to group patients by symptoms and former history of exacerbations. The concurrent detection of various biomarkers reflecting different pathobiological pathways might help recognize patients with an increased risk of death. Studies showed that obesity is related to decreased lung function in the general population due to respiratory mechanics, muscular discomfort, and breath control.
Material and Method: Ninety patients with COPD, whose mean age was 62, and 74% were male, were divided into four groups as A, B, C, and D according to the GOLD classification, were included in our study. Analyses were conducted to investigate the association between biochemical parameters, BMI, age, gender, and disease severity, according to GOLD subgroups.
Results: It has been demonstrated that COPD patients are generally over the age of 40 and age correlates with the severity of the disease consistent with previous studies. Our study has shown that COPD usually occurs over the age of 40, and there is a relationship between advanced age and the severity of COPD.
Conclusion: Our results are consistent with previous studies where COPD patients are usually over 40 years old, and age is linked to disease severity. While the BMI values of the patients in group B were higher than those of group A, it was compatible with studies showing the relationship between obesity and severity of COPD; being higher than C and D groups was consistent with the studies revealing the obesity paradox. Crp, Procalcitonin, Sedimentation, Calcium, Magnesium levels, and other complete blood count values showed no significant difference between GOLD groups.

Keywords

body mass index, complete blood count parameters, COPD

Project Number

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